Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Futoon Abedrabbu Al-Rawashde"'
Autor:
Futoon Abedrabbu Al-Rawashde, Ola M. Al-Sanabra, Moath Alqaraleh, Ahmad Q. Jaradat, Abdullah Saleh Al-Wajeeh, Muhammad Farid Johan, Wan Rohani Wan Taib, Imilia Ismail, Hamid Ali Nagi Al-Jamal
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 884 (2023)
The epigenetic silencing of tumor suppressor genes (TSGs) is critical in the development of chronic myeloid leukemia (CML). SHP-1 functions as a TSG and negatively regulates JAK/STAT signaling. Enhancement of SHP-1 expression by demethylation provide
Externí odkaz:
https://doaj.org/article/19355200a5a648b6bfe903e67a051535
Autor:
Hanan Kamel M. Saad, Wan Rohani Wan Taib, Azly Sumanty Ab Ghani, Imilia Ismail, Futoon Abedrabbu Al-Rawashde, Belal Almajali, Maysa Alhawamdeh, Alawiyah Awang Abd Rahman, Abdullah Saleh Al-wajeeh, Hamid Ali Nagi Al-Jamal
Publikováno v:
Diagnostics, Vol 13, Iss 7, p 1247 (2023)
Background: β-thalassaemia is a disorder caused by mutations in the β-globin gene, leading to defective production of haemoglobins (Hb) and red blood cells (RBCs). It is characterised by anaemia, ineffective erythropoiesis, and iron overload. Patie
Externí odkaz:
https://doaj.org/article/02a0af964a2a4d96b6915aaf84db6309
Autor:
Futoon Abedrabbu Al-Rawashde, Abdullah Saleh Al-wajeeh, Mansoureh Nazari Vishkaei, Hanan Kamel M. Saad, Muhammad Farid Johan, Wan Rohani Wan Taib, Imilia Ismail, Hamid Ali Nagi Al-Jamal
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1123 (2022)
Constitutive activation of Janus tyrosine kinase-signal transducer and activator of transcription (JAK/STAT) and Phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathways plays a crucial role in the developmen
Externí odkaz:
https://doaj.org/article/48cc5f21df914819bd5b47063ddc4801
Autor:
Belal Almajali, Muhammad Farid Johan, Abdullah Saleh Al-Wajeeh, Wan Rohani Wan Taib, Imilia Ismail, Maysa Alhawamdeh, Nafe M. Al-Tawarah, Wisam Nabeel Ibrahim, Futoon Abedrabbu Al-Rawashde, Hamid Ali Nagi Al-Jamal
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 307 (2022)
Overexpression of c-Myc plays an essential role in leukemogenesis and drug resistance, making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is impossible, and c-Myc upstream regulator pathways could be targeted inst
Externí odkaz:
https://doaj.org/article/6a4b4bdee89045569bac4d5d106e3a66
Autor:
Futoon Abedrabbu Al-Rawashde, Muhammad Farid Johan, Wan Rohani Wan Taib, Imilia Ismail, Syed Ahmad Tajudin Tuan Johari, Belal Almajali, Abdullah Saleh Al-wajeeh, Mansoureh Nazari Vishkaei, Hamid Ali Nagi Al-Jamal
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1287 (2021)
Epigenetic silencing of tumor suppressor genes (TSGs) plays an essential role in cancer pathogenesis, including acute myeloid leukemia (AML). All of SHP-1, SOCS-1, and SOCS-3 are TSGs that negatively regulate JAK/STAT signaling. Enhanced re-expressio
Externí odkaz:
https://doaj.org/article/052f0ad5009f4de5b866811ac4138394
Autor:
Al-Jamal, Futoon Abedrabbu Al-Rawashde, Ola M. Al-Sanabra, Moath Alqaraleh, Ahmad Q. Jaradat, Abdullah Saleh Al-Wajeeh, Muhammad Farid Johan, Wan Rohani Wan Taib, Imilia Ismail, Hamid Ali Nagi
Publikováno v:
Pharmaceuticals; Volume 16; Issue 6; Pages: 884
The epigenetic silencing of tumor suppressor genes (TSGs) is critical in the development of chronic myeloid leukemia (CML). SHP-1 functions as a TSG and negatively regulates JAK/STAT signaling. Enhancement of SHP-1 expression by demethylation provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::88fd02f7d5ca5c01755ded5139c0ab0d