Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Fusun N. Zeytin"'
Autor:
Fusun N. Zeytin, Scott F. Rusk
Publikováno v:
Endocrinology. 122:1129-1132
A clonal multipeptide-secreting cell line (44-2C) was used to study the interaction of basic fibroblast growth factor (bFGF) and GRF. The experiments were carried out in cells maintained under serum-free conditions in the absence of growth factors an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220b0d44b131a3a7830edd963b4bf854
https://doi.org/10.1210/endo-122-3-1129
https://doi.org/10.1210/endo-122-3-1129
Autor:
Fusun N. Zeytin, S. E. Leff, Andrew Baird, Scott F. Rusk, Tapio Haaparanta, Arnold J. Mandell, Vincent Raymond
Publikováno v:
Endocrinology. 122:1114-1120
The multipeptide-secreting 44-2C cell line maintains differentiated function when grown in a serum-free, growth factor- and hormone-deprived milieu. The cells continue to synthesize and secrete calcitonin (CT), CT gene-related peptide, neurotensin, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a8ee4ca74b8bdb336ad6a531c4411d
https://doi.org/10.1210/endo-122-3-1114
https://doi.org/10.1210/endo-122-3-1114
Publikováno v:
Biochemical and Biophysical Research Communications. 127:977-985
Summary The effect of GRF adenylate cyclase activation was studied in normal human, bovine and rat pituitary tissues. Human GRF(hGRF) activates adenylate cyclase in normal human pituitary membrane preparations in a concentration dependent manner (ED
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d906329423eaf348b9205e9b8a53c3cb
https://doi.org/10.1016/s0006-291x(85)80040-1
https://doi.org/10.1016/s0006-291x(85)80040-1
Autor:
Florence Reyl-Desmars, Fusun N. Zeytin
Publikováno v:
Biochemical and Biophysical Research Communications. 127:986-991
GH3 cells were used to study the effect of rat growth hormone-releasing factor on adenylate cyclase activity and its interaction with somatostatin. Rat GRF stimulates adenylate cyclase activity (ED5 0 = 6 X 10(-8) M) and somatostatin-14 inhibits this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35197503a45532d14252c917e64c4a1b
https://doi.org/10.1016/s0006-291x(85)80041-3
https://doi.org/10.1016/s0006-291x(85)80041-3
Autor:
Ram S. Bhatt, Ueli Gubler, Kenneth J. Collier, Fusun N. Zeytin, L P Gage, Beth J. Hoffman, F. Esch, Peter Bohlen, Mohindar S. Poonian, Nicholas Ling, John J. Monahan, P T Lomedico, Paul Brazeau
Publikováno v:
Proceedings of the National Academy of Sciences. 80:4311-4314
Molecular cloning has established the primary structures of two precursors of the human pancreas growth hormone-releasing factor (hpGRF-44), somatocrinin. Both polypeptides contain the sequence of hpGRF-44 flanked by basic processing sites. Furthermo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf61344315e4aa828339fc49eb181f5
https://doi.org/10.1073/pnas.80.14.4311
https://doi.org/10.1073/pnas.80.14.4311
Autor:
William B. Wehrenberg, Roger Guillemin, Nicholas Ling, Frederick Esch, Fusun N. Zeytin, Peter Bohlen, Paul Brazeau, Bertrand Bloch
Publikováno v:
Experimental Biology and Medicine. 175:407-413
Le facteur de liberation de la STH a ete caracterise et augmente dans plusieurs especes (homme, porc, bovin, souris). Le mecanisme d'action a ete defini. La cartographie des neurones a STH-LH a ete etablie. Des essais cliniques ont ete mis en route e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bb9290bf3383692601b23880561c71
https://doi.org/10.3181/00379727-175-41813
https://doi.org/10.3181/00379727-175-41813
Publikováno v:
Peptides. 7:165-167
We used a GH3 cell-line to compare the effects of rat GRF (rGRF) and VIP on the adenylate cyclase activity and to determine on what subunit the site of action of these two peptides is. In the GH3 cell-line, VIP was more potent than rGRF to stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5237e6f624370cd4c70bad69e4f884e
https://doi.org/10.1016/0196-9781(86)90180-4
https://doi.org/10.1016/0196-9781(86)90180-4
Publikováno v:
Biochemical and biophysical research communications. 127(3)
Summary GH 3 cells can be used effectively to study the in vitro mechanism of action of GRF. In these cells, there is a time and concentration-dependent release of cAMP into the medium. Rat hypothalamic GRF, (rGRF) is 7 to 10 fold more active than hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea73c7381a99f8ade9975f30bb8b13e
https://pubmed.ncbi.nlm.nih.gov/2985067
https://pubmed.ncbi.nlm.nih.gov/2985067
Publikováno v:
Endocrinology. 122(3)
A clonal cell line (44-2C) which synthesizes and secretes somatostatin, neurotensin, calcitonin (CT), and CT gene-related peptide and transiently expresses c-fos was used to characterize the mechanism of action of basic fibroblast growth factor (bFGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fe7470a57b5fac31bbb5cdd12072f0
https://pubmed.ncbi.nlm.nih.gov/2449340
https://pubmed.ncbi.nlm.nih.gov/2449340
Autor:
Nicholas Ling, Fusun N. Zeytin, Roger Guillemin, Andrew Baird, Frederick Esch, William B. Wehrenberg, Peter Bohlen, Paul Brazeau
Publikováno v:
Annual review of biochemistry. 54
PERSPECTIVES AND SUMMARy. . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 403 ISOLATION AND CHARACTERIZATION OF GRFs FROM TUMOR AND HYPOTHALAMIC TISSUE . . . . . . . . . . . ..
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f55f305686549fbcd08b631d908fe5d
https://pubmed.ncbi.nlm.nih.gov/2992358
https://pubmed.ncbi.nlm.nih.gov/2992358