Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Fushin X Yu"'
Autor:
Nan Gao, Rao Me, Theodore J. Standiford, Yangyang Zhang, Qing-Sheng Mi, Tingting Liu, Patrick Lee, Jie Wang, Fushin X Yu
Publikováno v:
J Immunol
The IL-36 cytokines are known to play various roles in mediating the immune response to infection in a tissue- and pathogen-dependent manner. The present study seeks to investigate the role of IL-36R signaling in C57BL/6 mouse corneas in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335c416a98c0a6342e785cf49164de37
https://europepmc.org/articles/PMC8612993/
https://europepmc.org/articles/PMC8612993/
Publikováno v:
Diabetes
The diabetic cornea exhibits pathological alterations, such as delayed epithelial wound healing and nerve regeneration. We investigated the role of semaphorin (SEMA) 3C in corneal wound healing and reinnervation in normal and diabetic B6 mice. Woundi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9069f2adabd7dcaa17b9dc6c3c004f8e
https://doi.org/10.2337/db18-1172
https://doi.org/10.2337/db18-1172
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Interleukin (IL)-36 cytokines have been shown to play either beneficial or detrimental roles in the infection of mucosal tissues in a pathogen-dependent manner, but their involvement in fungal keratitis remains elusive. We herein investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6009705ca0da6bc11282bbd7cf9282d8
http://europepmc.org/articles/PMC8114008
http://europepmc.org/articles/PMC8114008
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose IFN-stimulated gene (ISG) 15 is a type 1 IFN-induced protein and known to modify target proteins in a manner similar to ubiquitylation (protein conjugation by ISG15 is termed ISGylation). We sought to determine the role of ISG15 and its under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab81e7f4cc22193bcb4a0c6b78e5f301
http://europepmc.org/articles/PMC7405721
http://europepmc.org/articles/PMC7405721
Publikováno v:
The Journal of Immunology. 201:688-699
Pseudomonas aeruginosa keratitis is characterized by severe corneal ulceration and may lead to blindness if not treated properly in a timely manner. Although the roles of the IL-1 subfamily of cytokines are well established, as a newly discovered sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf5754ee4465a11968bbbafad8c5939
https://doi.org/10.4049/jimmunol.1800046
https://doi.org/10.4049/jimmunol.1800046
Publikováno v:
The Journal of Immunology. 198:3536-3547
The aim of this study was to elucidate the expression and functions of IL-17 in C57BL/6 mouse corneas in response to Pseudomonas aeruginosa infection. We found that P. aeruginosa infection induced and increased signaling of IL-23/23R/17/17R in mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa7836797344972fe3aac86b023931e4
https://doi.org/10.4049/jimmunol.1602087
https://doi.org/10.4049/jimmunol.1602087
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose ISG15, a di-ubiquitin-like protein, is critical for controlling certain viral and bacterial infections. We sought to determine if ISG15 plays a role in corneal innate immunity against Candida albicans (C. albicans) using a C57BL/6 (B6) mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6c10a4385555635c392e61a19e15b8
http://europepmc.org/articles/PMC5469425
http://europepmc.org/articles/PMC5469425
Autor:
Kazuhisa Takahashi, Michael W. Newstead, Xianying Zeng, Fushin X Yu, Theodore J. Standiford, Yuta Nanjo, Kazuhiro Tateda, Tetsuji Aoyagi
Publikováno v:
Infection and Immunity. 87
Legionella pneumophila causes life-threatening pneumonia culminating in acute lung injury. Innate and adaptive cytokines play an important role in host defense against L. pneumophila infection. Interleukin-36 (IL-36) cytokines are recently described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3eec7a970b1fdd547001f60597b8cb4
https://doi.org/10.1128/iai.00583-18
https://doi.org/10.1128/iai.00583-18
Autor:
Aditya Dandekar, Ze Zheng, Roberto Mendez, Xia Hou, Kezhong Zhang, Deyu Fang, Fushin X Yu, Fei Sun, Hyunbae Kim, Xuebao Zhang, Jie-Mei Wang, Ashok Kumar, Yining Qiu
Publikováno v:
Journal of Biological Chemistry. 291:23149-23158
Bacterial endotoxin can induce inflammatory and metabolic changes in the host. In this study, we revealed a molecular mechanism by which a stress-inducible, liver-enriched transcription factor, cAMP-responsive element-binding protein hepatic-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593e888612472de2e9e265f2bbf0407d
https://doi.org/10.1074/jbc.m116.755728
https://doi.org/10.1074/jbc.m116.755728
Autor:
Matthew Weiland, Jun Gu, Xilin Zhang, Qing-Sheng Mi, Jie Wang, Guihua Li, Li Zhou, Fushin X Yu, Queping Liu
Publikováno v:
Oncotarget
T cell immunoglobulin and mucin-4 (TIM-4), mainly expressed on dendritic cells (DC) and macrophages, plays an essential role in regulating immune responses. Langerhans cells (LC), which are the sole DC subpopulation residing at the epidermis, are pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68df7b8beede8a0610db519e2a8283aa
https://doi.org/10.18632/oncotarget.9546
https://doi.org/10.18632/oncotarget.9546