Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Furquan Shaheen"'
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40478 (2012)
Normal airway epithelial barrier function is maintained by cell-cell contacts which require the translocation of adhesion proteins at the cell surface, through membrane vesicle trafficking and fusion events. Myoferlin and dysferlin, members of the mu
Externí odkaz:
https://doaj.org/article/b93023dd9ebf4906bd2d612f847a0736
Autor:
Lynne A Murray, Tillie L Hackett, Stephanie M Warner, Furquan Shaheen, Rochelle L Argentieri, Paul Dudas, Francis X Farrell, Darryl A Knight
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e4039 (2008)
Bone morphogenic protein (BMP)-7 is a member of the BMP family which are structurally and functionally related, and part of the TGFbeta super family of growth factors. BMP-7 has been reported to inhibit renal fibrosis and TGFbeta1-induced epithelial-
Externí odkaz:
https://doaj.org/article/aaff4464c87b4da18f8a904246b05236
Autor:
Emmanuel T. Osei, Irene H. Heijink, Xian Li, Darren J. Cole, Corry-Anke Brandsma, Chen Xi Yang, Tillie-Louise Hackett, Leila B. Mostaço-Guidolin, Vicky Li, May Fouadi, Soheil M. Hajimohammadi, Geoffrey N. Maksym, David C. Walker, Fanny Chu, Furquan Shaheen, Jari Ullah
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, 200(4), 431-443. AMER THORACIC SOC
American Journal of Respiratory and Critical Care Medicine, 200(4), 431-443. AMER THORACIC SOC
RATIONALE: Histological stains have been used as the gold standard to visualize extracellular matrix (ECM) changes associated with airway remodeling in asthma, yet they provide no information on the biochemical and structural characteristics of the E
Autor:
Sarah E. Alcala, Ethan L. Matz, John F. Engelhardt, Furquan Shaheen, Jennifer L. Ingram, Claire E. Hoptay, Robert J. Freishtat, Tillie-Louise Hackett, Yulong Zhang, Dinesh K. Pillai, Sarah C. Ferrante
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 56:291-299
Limited in vivo models exist to investigate the lung airway epithelial role in repair, regeneration, and pathology of chronic lung diseases. Herein, we introduce a novel animal model in asthma-a xenograft system integrating a differentiating human as
Autor:
Jennifer L. Cross, Anthony Kicic, Fatemeh Moheimani, Philip M. Hansbro, Andrew T. Reid, Jeremy A. Hirota, Teal S. Hallstrand, Michael Kahn, Stephen M. Stick, Tillie-Louise Hackett, Stephanie M. Warner, Hollis M. Roth, Darryl A. Knight, Furquan Shaheen
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 68:59-69
The epithelium of asthmatics is characterized by reduced expression of E-cadherin and increased expression of the basal cell markers ck-5 and p63 that is indicative of a relatively undifferentiated repairing epithelium. This phenotype correlates with
Autor:
A. J. M. Van Oosterhout, Laura Hesse, Hyun-Kyoung Koo, Martijn C. Nawijn, Irene H. Heijink, May Fouadi, Virinchi N. S. Kuchibhotla, Furquan Shaheen, Tillie-Louise Hackett, S. Post, Bart N. Lambrecht
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, 8(1):13275. Nature Publishing Group
Scientific Reports
Scientific Reports, 8:13275. Nature Publishing Group
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, 8(1):13275. Nature Publishing Group
Scientific Reports
Scientific Reports, 8:13275. Nature Publishing Group
The airway epithelium regulates responses to aeroallergens, acting as a physical and immunological barrier. In asthma, epithelial barrier function and the expression of adherens junction protein E-cadherin is compromised, but it is unknown whether th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e1908f382f37e1d748158a65a61fec
https://biblio.ugent.be/publication/8582950/file/8582961
https://biblio.ugent.be/publication/8582950/file/8582961
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 51:830-839
Cigarette smoke-induced emphysema and small airway remodeling are the anatomic bases of chronic obstructive pulmonary disease (COPD), but the pathogenesis of these changes is unclear, and current treatments for COPD are minimally effective. To evalua
Autor:
Dorota Stefanowicz, Furquan Shaheen, Tillie-Louise Hackett, Teal S. Hallstrand, Nick Fishbane, Kevin Lee, Jari Ullah, Ekiomoado Olumese, Darryl A. Knight, Hyun-Kyoung Koo
Publikováno v:
BMC Pulmonary Medicine
Background: Recognition of the airway epithelium as a central mediator in the pathogenesis of asthma has necessitated greater understanding of the aberrant cellular mechanisms of the epithelium in asthma. The architecture of chromatin is integral to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1e198147a73ae028bd6823ede5058e
Autor:
Stefanowicz, Dorota, Ullah, Jari, Lee, Kevin, Furquan Shaheen, Ekiomoado Olumese, Fishbane, Nick, Hyun-Kyoung Koo, Teal Hallstrand, Knight, Darryl, Tillie-Louise Hackett
Comparison of epigenetic modifier gene expression between airway epithelial cells from asthmatic and healthy donors. (DOCX 15Â kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bf0ccffa04475bea429618b7dcddb27
Autor:
Stefanowicz, Dorota, Ullah, Jari, Lee, Kevin, Furquan Shaheen, Ekiomoado Olumese, Fishbane, Nick, Hyun-Kyoung Koo, Teal Hallstrand, Knight, Darryl, Tillie-Louise Hackett
Comparison of epigenetic modifier gene expression between epithelial cells and fibroblasts from healthy donors. (DOCX 17Â kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::badad9dd3c55be21644bf5be7a2d02d5