Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

Autor: Nho, K, Corneveaux, Jj, Kim, S, Lin, H, Risacher, Sl, Shen, L, Swaminathan, S, Ramanan, Vk, Liu, Y, Foroud, T, Inlow, Mh, Siniard, Al, Reiman, Ra, Aisen, Ps, Petersen, Rc, Green, Rc, Jack, Cr, Weiner, Mw, Baldwin, Ct, Lunetta, K, Farrer, La, for the Multi Institutional Research on Alzheimer Genetic Epidemiology Study, Furney, Sj, Lovestone, S, Simmons, A, Mecocci, Patrizia, Vellas, B, Tsolaki, M, Kloszewska, I, Soininen, H, for the AddNeuroMed Consortium, Mcdonald, Bc, Farlow, Mr, Ghetti, B, for the Indiana Memory, Aging, Study, Huentelman, Mj, Saykin, Aj

Publikováno v: Molecular psychiatry, vol 18, iss 7

Whole-exome sequencing of individuals with mild cognitive impairment, combined with genotype imputation, was used to identify coding variants other than the apolipoprotein E (APOE) ε4 allele associated with rate of hippocampal volume loss using an e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0efd800eb7599d0af39b1ddd5a02c7
https://doi.org/10.1038/mp.2013.24

A blood gene expression marker of early Alzheimer's disease.

Autor: Lunnon K, Sattlecker M, Furney SJ, Coppola G, Simmons A, Proitsi P, Lupton MK, Lourdusamy A, Johnston C, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Geschwind D, Lovestone S, Dobson R, Hodges A, Lunnon, Katie, Sattlecker, Martina

Publikováno v: Journal of Alzheimer's Disease; 2013, Vol. 33 Issue 1, p737-753, 17p

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Genome Sequencing of Multiple Primary Lung Cancers Harbouring Mixed Histology and Spontaneously Regressing Small-Cell Lung Cancer.

Autor: Thomas V; Genomic Oncology Research Group, Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.; Centre for Systems Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland., Rashed A; Our Lady of Lourdes Hospital, A92 VW28 Drogheda, Ireland.; Medical Oncology Group, Department of Molecular Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland., Faul C; St Luke's Radiation Oncology Network, D08 E797 Dublin, Ireland., Nicholson S; Department of Histopathology, St James's Hospital, D08 E797 Dublin, Ireland., Young V; Department of Cardiothoracic Surgery, St James's Hospital, D08 E797 Dublin, Ireland., Hanson J; Our Lady of Lourdes Hospital, A92 VW28 Drogheda, Ireland., Hennessy BT; Our Lady of Lourdes Hospital, A92 VW28 Drogheda, Ireland.; Medical Oncology Group, Department of Molecular Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland., Toomey S; Medical Oncology Group, Department of Molecular Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland., Furney SJ; Genomic Oncology Research Group, Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.; Centre for Systems Medicine, RCSI University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.

Publikováno v: Journal of personalized medicine [J Pers Med] 2024 Feb 28; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 28.

Testing for pharmacogenomic predictors of ppRNFL thinning in individuals exposed to vigabatrin.

Autor: Boothman I; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.; The SFI Futureneuro Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland.; The SFI Centre for Research Training in Genomics Data Science, Galway, Ireland., Clayton LM; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Bucks, United Kingdom., McCormack M; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., Driscoll AM; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., Stevelink R; Department of Genetics, University Medical Center Utrecht, Utrecht, Netherlands., Moloney P; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., Krause R; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., Kunz WS; Division of Neurochemistry, Department of Epileptology, University Bonn Medical Center, Bonn, Germany., Diehl S; Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., O'Brien TJ; Departments of Neuroscience and Neurology, Central Clinical School, The Alfred Hospital, Monash University, Melbourne, VIC, Australia., Sills GJ; School of Life Sciences, University of Glasgow, Glasgow, United Kingdom., de Haan GJ; Stichting Epilepsie Instellingen Nederland (SEIN), Heemstede, Netherlands., Zara F; 'IRCCS'G. Gaslini' Institute, Genova, Italy.; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genova, Italy., Koeleman BP; Department of Genetics, University Medical Center Utrecht, Utrecht, Netherlands., Depondt C; Department of Neurology, Hôpital Erasme, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles, Brussels, Belgium., Marson AG; Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, United Kingdom., Stefansson H; deCODE Genetics, Reykjavik, Iceland., Stefansson K; deCODE Genetics, Reykjavik, Iceland., Craig J; Department of Neurology, Royal Victoria Hospital, Belfast Health and Social Care Trust, Belfast, United Kingdom., Johnson MR; Division of Brain Sciences, Imperial College Faculty of Medicine, London, United Kingdom., Striano P; 'IRCCS'G. Gaslini' Institute, Genova, Italy.; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genova, Italy., Lerche H; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany., Furney SJ; Genomic Oncology Research Group, Deptartment of Physiology and Medical Physics, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland., Delanty N; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland., Sisodiya SM; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Bucks, United Kingdom., Cavalleri GL; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.; The SFI Futureneuro Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland.; The SFI Centre for Research Training in Genomics Data Science, Galway, Ireland.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2023 Sep 08; Vol. 17, pp. 1156362. Date of Electronic Publication: 2023 Sep 08 (Print Publication: 2023).