Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Furkan Guvenc"'
Autor:
Subha Dahal, Kiera Clayton, Terek Been, Raphaële Fernet-Brochu, Alonso Villasmil Ocando, Ahalya Balachandran, Mikaël Poirier, Rebecca Kaddis Maldonado, Lulzim Shkreta, Kayluz Frias Boligan, Furkan Guvenc, Fariha Rahman, Donald Branch, Brendan Bell, Benoit Chabot, Scott D. Gray-Owen, Leslie J. Parent, Alan Cochrane
Publikováno v:
Retrovirology, Vol 19, Iss 1, Pp 1-25 (2022)
Plain Language Summary Identifying cellular factors that regulate HIV-1 RNA processing provides important insights into novel strategies to control this infection. Different members of the SR kinase family have distinct roles in regulating virus expr
Externí odkaz:
https://doaj.org/article/f6c59f5364bf49b0a2fb808840fdf7ed
Autor:
Katherine Chan, Adrian Granda Farias, Hunsang Lee, Furkan Guvenc, Patricia Mero, Kevin R. Brown, Henry Ward, Maximilian Billmann, Kamaldeep Aulakh, Audrey Astori, Shahan Haider, Edyta Marcon, Ulrich Braunschweig, Shuye Pu, Andrea Habsid, Amy Hin Yan Tong, Natasha Christie-Holmes, Patrick Budylowski, Ayoob Ghalami, Samira Mubareka, Finlay Maguire, Arinjay Banerjee, Karen L. Mossman, Jack Greenblatt, Scott D. Gray-Owen, Brian Raught, Benjamin J. Blencowe, Mikko Taipale, Chad Myers, Jason Moffat
Publikováno v:
Heliyon, Vol 9, Iss 1, Pp e12744- (2023)
SARS-CoV-2 depends on host cell components for infection and replication. Identification of virus-host dependencies offers an effective way to elucidate mechanisms involved in viral infection and replication. If druggable, host factor dependencies ma
Externí odkaz:
https://doaj.org/article/1fc0974096af4f23af93d99b3d0085a0
Autor:
Edurne Rujas, Iga Kucharska, Yong Zi Tan, Samir Benlekbir, Hong Cui, Tiantian Zhao, Gregory A. Wasney, Patrick Budylowski, Furkan Guvenc, Jocelyn C. Newton, Taylor Sicard, Anthony Semesi, Krithika Muthuraman, Amy Nouanesengsy, Clare Burn Aschner, Katherine Prieto, Stephanie A. Bueler, Sawsan Youssef, Sindy Liao-Chan, Jacob Glanville, Natasha Christie-Holmes, Samira Mubareka, Scott D. Gray-Owen, John L. Rubinstein, Bebhinn Treanor, Jean-Philippe Julien
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Here, the authors combine three different antibody specificities and an Fc domain on a single multivalent molecule, resulting in high neutralization activity despite viral sequence variability.
Externí odkaz:
https://doaj.org/article/21239c53aca444dbbc85f54151271ca5
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
While the global incidence of human immunodeficiency virus (HIV-1) remains well above UNAIDS targets, sexual transmission HIV is surprisingly inefficient. A variety of host, viral and environmental factors can either increase HIV-1 shedding in the in
Externí odkaz:
https://doaj.org/article/b5fb10a418c045b7861849d185d26680
Autor:
Ferah Budak, S Haldun Bal, Gulcin Tezcan, Furkan Guvenc, E Halis Akalin, Guher Goral, Gunnur Deniz, H Barbaros Oral
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165138 (2016)
Although our knowledge about Brucella virulence factors and the host response increase rapidly, the mechanisms of immune evasion by the pathogen and causes of chronic disease are still unknown. Here, we aimed to investigate the immunological factors
Externí odkaz:
https://doaj.org/article/1b8e81ef39d046ba854e47f6cbafb729
Autor:
Stephenie Naugler, Shannon E. McCaw, Furkan Guvenc, Ayoob Ghalami, Steven Hayes, Rachel Tyli, Betty P.K. Poon, Natasha Christie-Holmes, Rita A. Kandel, Amit Weiner, Mary Speck, Ori D. Rotstein, Scott D. Gray-Owen, James A. Scott, Allen Rainville, Patrick Budylowski, Samira Mubareka
Publikováno v:
American Journal of Infection Control
Background The COVID-19 pandemic highlighted the need for evidence-based approaches to decontamination and reuse of N95 filtering facepiece respirators (FFRs). We sought to determine whether vapourized hydrogen peroxide (VHP) reduced SARS-CoV-2 biobu
Autor:
Furkan Guvenc, Scott D. Gray-Owen, Patrick Budylowski, Natasha Christie-Holmes, Deborah L O'Connor, Sharon Unger, Samira Mubareka
Publikováno v:
CMAJ
Background: Provision of pasteurized donor human milk, as a bridge to mother’s own milk, is the standard of care for very low-birth-weight infants in hospital. The aim of this research was to confirm that Holder pasteurization (62.5°C for 30 min)
Autor:
Hasan Kocaeli, Seref Dogan, Haluk Barbaros Oral, Furkan Guvenc, Arzu Yilmaztepe Oral, Sibel Yorulmaz Goktas, Emin Halis Akalin, Selcuk Yilmazlar, Emel Yilmaz, Güven Özkaya
Publikováno v:
Singapore medical journal.
Introduction: This study aims to determine the diagnostic value of IL-6, IL-8, IL-17, TNF-α and D-lactate levels in the cerebrospinal fluid (CSF) in nosocomial meningitis. Methods: CSF levels of cytokines and D-lactate were compared across 29 episod
Autor:
Katherine Chan, Adrian Granda Farias, Hunsang Lee, Furkan Guvenc, Patricia Mero, Kamaldeep Aulakh, Kevin R. Brown, Shahan Haider, Edyta Marcon, Ulrich Braunschweig, Amy Hin Yan Tong, Shuye Pu, Andrea Habsid, Natasha Christie-Holmes, Patrick Budylowski, Audrey Astori, Ayoob Ghalami, Samira Mubareka, Arinjay Banerjee, Karen L. Mossman, Jack Greenblatt, Scott D. Gray-Owen, Brian Raught, Benjamin J. Blencowe, Mikko Taipale, Jason Moffat
SUMMARYSARS-CoV-2, depends on host cell components for replication, therefore the identification of virus-host dependencies offers an effective way to elucidate mechanisms involved in viral infection. Such host factors may be necessary for infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c404dd92076179177cbf643a9df0d18
https://doi.org/10.1101/2021.06.28.450244
https://doi.org/10.1101/2021.06.28.450244
Autor:
Samir Benlekbir, Katherine Prieto, Krithika Muthuraman, Furkan Guvenc, Edurne Rujas, Jean-Philippe Julien, Natasha Christie-Holmes, Jacob Glanville, Gregory A. Wasney, Patrick Budylowski, Samira Mubareka, Sawsan Youssef, Anthony Semesi, Amy Nouanesengsy, Clare Burn Aschner, Scott D. Gray-Owen, John L. Rubinstein, Hong Cui, Stephanie A. Bueler, Yong Zi Tan, Taylor Sicard, Sindy Liao-Chan, Bebhinn Treanor, Iga Kucharska, Jocelyn C. Newton, Tiantian Zhao
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Nature Communications
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Nature Communications
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
SARS-CoV-2, the virus responsible for COVID-19, has caused a global pandemic. Antibodies can be powerful biotherapeutics to fight viral infections. Here, we use the human apoferritin protomer as a modular subunit to drive oligomerization of antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5722cdeb8e6fa77a947f721a9d3ec314
http://hdl.handle.net/10810/52013
http://hdl.handle.net/10810/52013