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The Role of 20-HETE, COX, Thromboxane Receptors, and Blood Plasma Antioxidant Status in Vascular Relaxation of Copper-Nanoparticle-Fed WKY Rats

Autor: Magdalena Krajewska-Włodarczyk, Michał Majewski, Leszek Gromadziński, Katarzyna Socha, Jerzy Juśkiewicz, Ewelina Cholewińska, Katarzyna Ognik

Publikováno v: Nutrients
Volume 13
Issue 11
Nutrients, Vol 13, Iss 3793, p 3793 (2021)

Recently, the addition of copper nanoparticles (NPs) in a daily diet (6.5 mg/kg) was studied in different animal models as a possible alternative to ionic forms. Male Wistar–Kyoto rats (24-week-old, n = 11) were fed with copper, either in the form

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174b10ec46b23f2c960c646141583810
https://doi.org/10.3390/nu13113793

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Furegrelate, a thromboxane synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets

Autor: Dinesh K. Hirenallur-S., Jeaninne T. Leming, Neil D. Detweiler, John B. Gordon, Steven T. Haworth, Nancy J. Rusch

Publikováno v: Pulmonary Circulation

The development of pulmonary arterial hypertension (PAH) in pediatric patients has been linked to the production of the arachidonic acid metabolite, thromboxane A(2) (TxA(2)). The present study evaluated the therapeutic effect of furegrelate sodium,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01412a4de63f2e9d98d24953acdac6dc
http://europepmc.org/articles/PMC3401873

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The Effects Of Centrally Injected Arachidonic Acid On Respiratory System: Involvement Of Cyclooxygenase To Thromboxane Signaling Pathway

Autor: Leman Gizem Erkan, Murat Yalcin, Gokcen Guvenc, Nasir Niaz, Burcin Altinbas

Arachidonic acid (AA) is a polyunsaturated fatty acid that is present in the phospholipids of the cell membranes of the body and is abundant in the brain. Exogenously administered AA has been shown to affect brain metabolism and to exhibit cardiovasc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c2aecd458b5659ec7c58c62299e0f0
https://aperta.ulakbim.gov.tr/record/59423

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Changes in glomerular thromboxane A2 receptor expression and ligand binding following immune injury

Autor: Barbara A. Bresnahan, Sheng-Hua Wu, Shelly Dufek, Elias A. Lianos

Publikováno v: Kidney International. 55(1):139-147

Changes in glomerular thromboxane A 2 receptor expression and ligand binding following immune injury. Background Thromboxane (Tx) A 2 is a potent vasoconstrictor eicosanoid that attains high levels within nephritic glomeruli and mediates a drop in gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024126a007c97553148be144bf12eab7

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The role of the central arachidonic acid-thromboxane A(2) cascade in cardiovascular regulation during hemorrhagic shock in rats

Autor: Cenk Aydin, Murat Yalcin

The aim of the current study was to elucidate the underlying central mechanism(s) of the cardiovascular effects evoked by centrally injected melittin and arachidonic acid (AA) in hemorrhaged hypotensive condition, specifically, from central AA releas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea2e743648ef2fb9662ad3b70f830ba
http://hdl.handle.net/11452/23776

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Central Mechanism Underlying Pressor And Bradycardic Effect Of Intracerebroventricularly Injected Arachidonic Acid

Autor: Murat Yalcin

The aim of the current study was to determine the central cyclooxygenase (COX) pathway and central thromboxane signaling in the cardiovascular effects evoked by arachidonic acid (AA). As a main control for the study, different doses of AA (75, 150, o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134d1fe846de83ddba95cb767e8a11c9
https://aperta.ulakbim.gov.tr/record/18169

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