Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Fuquan Hu"'
Autor:
Yuhui Yang, Wei Shen, Qiu Zhong, Qian Chen, Xuesong He, Jonathon L. Baker, Kun Xiong, Xiaoling Jin, Jing Wang, Fuquan Hu, Shuai Le
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
With the emergence of multidrug-resistant and extensively drug-resistant bacterial pathogens, phage therapy and other alternative or additional therapeutic modalities are receiving resurgent attention. One of the major obstacles in developing effecti
Externí odkaz:
https://doaj.org/article/7f35ba77104347f6bf7a1c8d9f56cfbb
Autor:
Supeng Yin, Bei Jiang, Guangtao Huang, Yulong Zhang, Bo You, Yu Chen, Yali Gong, Jing Chen, Zhiqiang Yuan, Yan Zhao, Ming Li, Fuquan Hu, Zichen Yang, Yizhi Peng
Publikováno v:
Cellular Physiology and Biochemistry, Vol 45, Iss 4, Pp 1399-1409 (2018)
Background/Aims: N-acetylcysteine (NAC) is a novel and promising agent with activity against bacterial biofilms. Human serum also inhibits biofilm formation by some bacteria. We tested whether the combination of NAC and human serum offers greater ant
Externí odkaz:
https://doaj.org/article/ea38132a835741a1a5f7ac8ea45e16a7
Phage Abp1 Rescues Human Cells and Mice from Infection by Pan-Drug Resistant Acinetobacter Baumannii
Autor:
Supeng Yin, Guangtao Huang, Yulong Zhang, Bei Jiang, Zichen Yang, Zhiwei Dong, Bo You, Zhiqiang Yuan, Fuquan Hu, Yan Zhao, Yizhi Peng
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 6, Pp 2337-2345 (2017)
Background/Aims: As an “ESKAPE” pathogen, Acinetobacter baumannii is one of the leading causes of drug-resistant infections in humans. Phage therapy may be a useful strategy in treating infections caused by drug-resistant A. baumannii. Among 21 p
Externí odkaz:
https://doaj.org/article/d043ff330d76455480ff94928977336c
Autor:
Yifei Lu, Hongxiang Yan, Jiezhong Deng, Zhigang Huang, Xurui Jin, Yanlan Yu, Qiwen Hu, Fuquan Hu, Jing Wang
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background Lactococcus lactis is a food grade probiotics and widely used to express heterologous proteins. Generally, target genes are knocked into the L. lactis genome through double-crossover recombination to express heterologous proteins
Externí odkaz:
https://doaj.org/article/be0926e793494edd83e72d9e309e2eb6
Autor:
Chaofei Tang, Chuanjiang Deng, Yi Zhang, Cong Xiao, Jing Wang, Xiancai Rao, Fuquan Hu, Shuguang Lu
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Phages have attracted a renewed interest as alternative to chemical antibiotics. Although the number of phages is 10-fold higher than that of bacteria, the number of genomically characterized phages is far less than that of bacteria. In this study, p
Externí odkaz:
https://doaj.org/article/19ae6db234eb4209ae20950f4f60b5f5
Autor:
Yuhui Yang, Shuai Le, Wei Shen, Qian Chen, Youying Huang, Shuguang Lu, Yinling Tan, Ming Li, Fuquan Hu, Yang Li
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Multidrug-resistant Pseudomonas aeruginosa is one of the most life-threatening pathogens for global health. In this regard, phage encoded lytic proteins, including endolysins and virion-associated peptidoglycan hydrolases (VAPGH), have been proposed
Externí odkaz:
https://doaj.org/article/ea674249bf0243ce8fa7db8871aa28d0
Autor:
Gang Li, Mengyu Shen, Yuhui Yang, Shuai Le, Ming Li, Jing Wang, Yan Zhao, Yinling Tan, Fuquan Hu, Shuguang Lu
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Adaptation of bacteria to phage predation poses a major obstacle for phage therapy. Bacteria adopt multiple mechanisms, such as inhibition of phage adsorption and CRISPR/Cas systems, to resist phage infection. Here, a phage-resistant mutant of Pseudo
Externí odkaz:
https://doaj.org/article/66bd6b1d25a44d11a7dcdcb92602b222
Autor:
Supeng Yin, Ping Chen, Bo You, Yulong Zhang, Bei Jiang, Guangtao Huang, Zichen Yang, Yu Chen, Jing Chen, Zhiqiang Yuan, Yan Zhao, Ming Li, Fuquan Hu, Yali Gong, Yizhi Peng
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Pseudomonas aeruginosa is the leading cause of infection in burn patients. The increasing carbapenem resistance of P. aeruginosa has become a serious challenge to clinicians. The present study investigated the molecular typing and carbapenem resistan
Externí odkaz:
https://doaj.org/article/f14dede517ce4281966f6d31a5c59f72
Autor:
Supeng Yin, Bei Jiang, Guangtao Huang, Yali Gong, Bo You, Zichen Yang, Yu Chen, Jing Chen, Zhiqiang Yuan, Ming Li, Fuquan Hu, Yan Zhao, Yizhi Peng
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Staphylococcus aureus is a common pathogen isolated from burn patients that can form biofilms on burn wounds and implanted deep vein catheters, which often leads to refractory infections or even biofilm-related sepsis. As biofilm formation is usually
Externí odkaz:
https://doaj.org/article/7bbacb7181884feba5595876404903f7
Autor:
Gang Li, Shuguang Lu, Mengyu Shen, Shuai Le, Wei Shen, Yinling Tan, Jing Wang, Xia Zhao, Yan Zhao, Yali Gong, Yuhui Yang, Hongbin Zhu, Fuquan Hu, Ming Li
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174429 (2017)
Prophages are major contributors to horizontal gene transfer and drive the evolution and diversification of bacteria. Here, we describe the characterization of a prophage element designated pp3 in the clinical Pseudomonas aeruginosa isolate PA1. pp3
Externí odkaz:
https://doaj.org/article/a7fdff5f6d5147fcbe372efc409cf0b4