Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Fuping You"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Viral infections pose significant public health challenges, exemplified by the global impact of COVID-19 caused by SARS-CoV-2. Understanding the intricate molecular mechanisms governing virus-host interactions is pivotal for effective interv
Externí odkaz:
https://doaj.org/article/15b8aa9d97b948668533d352db8a4bd1
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Endogenous retroviruses (ERVs) derived from the long terminal repeat (LTR) family of transposons constitute a significant portion of the mammalian genome, with origins tracing back to ancient viral infections. Despite comprising approximately 8% of t
Externí odkaz:
https://doaj.org/article/6629bff23922481a8e174d03b30f79cb
Autor:
Huan Wang, Yiming Wang, Jiongyuan Li, Ziyi He, Sarah A. Boswell, Mirra Chung, Fuping You, Sen Han
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Background Tyrosine kinase inhibitors (TKIs) are anti-cancer therapeutics often prescribed for long-term treatment. Many of these treatments cause cardiotoxicity with limited cure. We aim to clarify molecular mechanisms of TKI-induced cardio
Externí odkaz:
https://doaj.org/article/96fac43db70b418382c36d847c4bcc4f
Autor:
Jinfeng Liu, Jiaxin Xiang, Cuiyuan Jin, Lusha Ye, Lei Wang, Yanan Gao, Nianyin Lv, Junfeng Zhang, Fuping You, Hongzhi Qiao, Liyun Shi
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Plant-derived nanovesicles (PDNVs) have been proposed as a major mechanism for the inter-kingdom interaction and communication, but the effector components enclosed in the vesicles and the mechanisms involved are largely unknown. The plant A
Externí odkaz:
https://doaj.org/article/4340a5697590498e864c6ff5a1fb562e
Autor:
Jia Song, Yuning Zhang, Yunyang Bai, Xiaowen Sun, Yanhui Lu, Yusi Guo, Ying He, Min Gao, Xiaopei Chi, Boon Chin Heng, Xin Zhang, Wenjing Li, Mingming Xu, Yan Wei, Fuping You, Xuehui Zhang, Dan Lu, Xuliang Deng
Publikováno v:
Advanced Science, Vol 10, Iss 30, Pp n/a-n/a (2023)
Abstract Tissue‐infiltrating neutrophils (TINs) secrete various signaling molecules to establish paracrine communication within the inflammatory milieu. It is imperative to identify molecular mediators that control this secretory phenotype of TINs.
Externí odkaz:
https://doaj.org/article/07988048f1ed461d93cbbee76dd341b3
Autor:
Yunfei Li, Junjie Xu, Xuefei Guo, Zhiwei Li, Lili Cao, Shengde Liu, Ying Guo, Guodong Wang, Yujie Luo, Zeming Zhang, Xuemei Wei, Yingchi Zhao, Tongtong Liu, Xiao Wang, Huawei Xia, Ming Kuang, Qirui Guo, Junhong Li, Luoying Chen, Yibing Wang, Qi Li, Fengchao Wang, Qinghua Liu, Fuping You
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract Background The CRISPR-Cas13 system is an RNA-guided RNA-targeting system and has been widely used in transcriptome engineering with potentially important clinical applications. However, it is still controversial whether Cas13 exhibits collat
Externí odkaz:
https://doaj.org/article/f4bbc7d8d9cb40f3904f0c1e02132bd1
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionThe increased prevalence of non-alcoholic fatty liver disease (NAFLD) and sarcopenia among the elderly are facing a significant challenge to the world’s health systems. Our study aims to identify the coexpressed genes in NAFLD and sarco
Externí odkaz:
https://doaj.org/article/4d71129bd75f475499a430eacd6f68a4
Autor:
Siji Li, Lili Cao, Zeming Zhang, Ming Kuang, Luoying Chen, Yingchi Zhao, Yujie Luo, Zhinan Yin, Fuping You
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-12 (2021)
Abstract The innate immune system is the first line of host defense, which responds rapidly to viral infection. Innate recognition of viruses is mediated by a set of pattern recognition receptors (PRRs) that sense viral genomic nucleic acids and/or r
Externí odkaz:
https://doaj.org/article/3a39a3679bf74432894e4ae64cddd0e5
Autor:
Zhiwei Li, Guanwen Li, Yunfei Li, Yujie Luo, Yuhan Jiang, Ziyu Zhang, Ziyi Zhou, Shengde Liu, Chen Wu, Fuping You
Publikováno v:
Viruses, Vol 15, Iss 8, p 1761 (2023)
OTUD6A is a deubiquitinase that plays crucial roles in various human diseases. However, the precise regulatory mechanism of OTUD6A remains unclear. In this study, we found that OTUD6A significantly inhibited the production of type I interferon. Consi
Externí odkaz:
https://doaj.org/article/c66d6b58ec5d44b4839668e9e23a6288
Autor:
Tongtong Fu, Zheng Fan, Yujie Li, Zhoufei Li, Hanqing Zhao, Yanling Feng, Guanhua Xue, Jinghua Cui, Chao Yan, Lin Gan, Junxia Feng, Jing Yuan, Fuping You
Publikováno v:
Microorganisms, Vol 11, Iss 7, p 1656 (2023)
Staphylococcus aureus is an opportunistic human pathogen that is often involved in severe infections such as pneumonia and sepsis in which bacterial virulence factors play a key role. Infections caused by S. aureus are often difficult to eradicate, p
Externí odkaz:
https://doaj.org/article/d18ca2cf20b8480f88fb686d2f79aa20