Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Funmei Yang"'
Publikováno v:
Biological Research, Vol 39, Iss 1, Pp 67-77 (2006)
Iron is essential for many aspects of cellular function. However, it also can generate oxygen-based free radicals that result in injury to biological molecules. For this reason, iron acquisition and distribution are tightly regulated. Constant exposu
Externí odkaz:
https://doaj.org/article/14f01eb7e5594346963eb417bf93b3ee
Autor:
Jacqueline G. Stonehuerner, Kimberly D. Callaghan, Andrew J. Ghio, David J. Haile, Funmei Yang, Judy H. Richards, Ngoc Bich Nguyen
Publikováno v:
BioMetals. 23:657-667
Exposure to bleomycin can result in an inflammatory lung injury. The biological effect of this anti-neoplastic agent is dependent on its coordination of iron with subsequent oxidant generation. In lung cells, divalent metal transporter 1 (DMT1) can p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230acdede89e6216edda9fcb895f0362
https://doi.org/10.1007/s10534-010-9326-0
https://doi.org/10.1007/s10534-010-9326-0
Autor:
Kimberly D. Callaghan, Zhongping Deng, Ngoc Bich Nguyen, Andrew J. Ghio, Michael D. Madden, Jacqueline G. Stonehuerner, Funmei Yang, Lisa A. Dailey, Claude A. Piantadosi, Judy H. Richards
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 38:715-723
The dissociation of iron from heme is a major factor in iron metabolism and the cellular concentrations of the metal correlate with heme degradation. We tested the hypotheses that (1) exposure to a product of heme catabolism, carbon monoxide (CO), al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b95ae21a30717edf7fc0bd475126ee0
https://doi.org/10.1165/rcmb.2007-0179oc
https://doi.org/10.1165/rcmb.2007-0179oc
Autor:
Frank J. Weaker, Funmei Yang, Christi A. Walter, Gwendolyn S. Adrian, LeAnn K. Robinson, Barbara H. Bowman, Erle K. Adrian, Damon C. Herbert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::856d72af140e822d5963dad9bb408faa
https://doi.org/10.1159/000419347
https://doi.org/10.1159/000419347
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 291:L417-L425
Alveolar macrophages express many proteins important in iron homeostasis, including the iron importer divalent metal transport 1 (DMT1) and the iron exporter ferroportin 1 (FPN1) that likely participate in lung defense. We found the iron regulatory h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cabe0c35fe86654f9caba2e4701c326
https://doi.org/10.1152/ajplung.00484.2005
https://doi.org/10.1152/ajplung.00484.2005
Publikováno v:
Biological Research, Vol 39, Iss 1, Pp 67-77 (2006)
Biological Research v.39 n.1 2006
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Volume: 39, Issue: 1, Pages: 67-77, Published: 2006
Biological Research v.39 n.1 2006
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Volume: 39, Issue: 1, Pages: 67-77, Published: 2006
Iron is essential for many aspects of cellular function. However, it also can generate oxygen-based free radicals that result in injury to biological molecules. For this reason, iron acquisition and distribution are tightly regulated. Constant exposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab81046e27d3da8fb285888762c4c86
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100008
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100008
Autor:
Michael C. Madden, Lisa A. Dailey, Funmei Yang, Kevin G. Dolan, Michael D. Garrick, Laura M. Garrick, Xinchao Wang, Claude A. Piantadosi, Andrew J. Ghio, Jacqueline D. Stonehuerner
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 289:L460-L467
Exposure to airborne particulates makes the detoxification of metals a continuous challenge for the lungs. Based on the fate of iron in airway epithelial cells, we postulated that divalent metal transporter-1 (DMT1) participates in detoxification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4defdebb3bf42c52060f13059421bf9
https://doi.org/10.1152/ajplung.00154.2005
https://doi.org/10.1152/ajplung.00154.2005
Autor:
Lisa A. Dailey, Michael D. Garrick, Claude A. Piantadosi, Funmei Yang, Xinchao Wang, Andrew J. Ghio
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 289:L24-L33
Regulation of the metal transport protein divalent metal transporter-1 (DMT1) may contribute to the uptake and detoxification of iron by cells resident in the respiratory tract. Inflammation has been associated with an increased availability of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c3aafdf8c90e194bc1b8fae7047469
https://doi.org/10.1152/ajplung.00428.2003
https://doi.org/10.1152/ajplung.00428.2003
Publikováno v:
Blood Cells, Molecules, and Diseases. 35:47-56
Acute and chronic inflammatory states are associated with many changes in intracellular iron metabolism including sequestration of iron in the mononuclear-phagocyte system (MPS) and a decline in serum iron. Previous work in rodent models of acute inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6ff048963b26a429b817bfd8c23db2
https://doi.org/10.1016/j.bcmd.2005.04.006
https://doi.org/10.1016/j.bcmd.2005.04.006
Publikováno v:
Free Radical Biology and Medicine. 36:850-857
Iron is critical for many aspects of cellular function, but it can also generate reactive oxygen species that can damage biological macromolecules. To limit oxidative stress, iron acquisition and its distribution must be tightly regulated. In the lun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf27d991bb7b917ae67a079a0bfe83e7
https://doi.org/10.1016/j.freeradbiomed.2003.12.008
https://doi.org/10.1016/j.freeradbiomed.2003.12.008