A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro

Autor: Aillaud, Isabelle, Kaniyappan, Senthilvelrajan, Chandupatla, Ram Reddy, Ramirez, Lisa Marie, Alkhashrom, Sewar, Eichler, Jutta, Horn, Anselm H C, Zweckstetter, Markus, Mandelkow, Eckhard, Sticht, Heinrich, Funke, Susanne Aileen

Publikováno v: Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-19 (2022)
Alzheimer's research & therapy 14(1), 15 (2022). doi:10.1186/s13195-022-00959-z

Background Alzheimer’s disease (AD), the most common form of dementia, is a progressive neurodegenerative disorder that mainly affects older adults. One of the pathological hallmarks of AD is abnormally aggregated Tau protein that forms fibrillar d

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Selection of Listeria monocytogenes InlA-Binding Peptides Using Phage Display—Novel Compounds for Diagnostic Applications?

Autor: Kenzel, Julia, Brüggemann, Dagmar Adeline, Funke, Susanne Aileen

Publikováno v: Applied Microbiology (2673-8007); Dec2022, Vol. 2 Issue 4, p921-933, 13p

Purification of recombinantly expressed and cytotoxic human amyloid-beta peptide 1–42

Autor: Wiesehan, Katja, Funke, Susanne Aileen, Fries, Miriam, Willbold, Dieter

Publikováno v: In Journal of Chromatography B 2007 856(1):229-233

Detection of Soluble Amyloid-β Oligomers and Insoluble High-Molecular-Weight Particles in CSF: Development of Methods with Potential for Diagnosis and Therapy Monitoring of Alzheimer's Disease.

Autor: Funke, Susanne Aileen¹ a.funke@fz-juelich.de

Publikováno v: International Journal of Alzheimer's Disease. 2011, Vol. 2011, p1-8. 8p. 1 Diagram.