Zobrazeno 1 - 10
of 372
pro vyhledávání: '"Fungal vaccine"'
Autor:
Jéssica L. Chechi, Felipe A. C. da Costa, Julia M. Figueiredo, Cássia M. de Souza, Alessandro F. Valdez, Daniel Zamith-Miranda, Aline C. Camara, Carlos P. Taborda, Joshua D. Nosanchuk
Publikováno v:
Expert Review of Vaccines, Vol 22, Iss 1, Pp 1136-1153 (2023)
ABSTRACTIntroduction Fungal infections are caused by a broad range of pathogenic fungi that are found worldwide with different geographic distributions, incidences, and mortality rates. Considering that there are relatively few approved medications a
Externí odkaz:
https://doaj.org/article/a5f91ceada72428b90589862c5045897
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cryptococcus neoformans and C. gattii, the etiologic agents of cryptococcosis, cause over 100,000 deaths worldwide every year, yet no cryptococcal vaccine has progressed to clinical trials. In preclinical studies, mice vaccinated with an attenuated s
Externí odkaz:
https://doaj.org/article/cd822e4aaf3044ae875264ba6359ba7b
Publikováno v:
The Cell Surface, Vol 10, Iss , Pp 100114- (2023)
Externí odkaz:
https://doaj.org/article/cbc83de8b7984661868fdb7d470ecb2a
Autor:
Chao Li, Yang Meng, Hailong Li, Wei Du, Xindi Gao, Chenhao Suo, Yiru Gao, Yue Ni, Tianshu Sun, Sheng Yang, Tian Lan, Meiling Xin, Chen Ding
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Systemic infection with Cryptococcus neoformans, a dangerous and contagious pathogen found throughout the world, frequently results in lethal cryptococcal pneumonia and meningoencephalitis, and no effective treatments and vaccination of cryptococcosi
Externí odkaz:
https://doaj.org/article/fa073cd5159f48aca583e04047ebee63
Autor:
Robert A. Cramer
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Human fungal infections (mycoses) cause significant morbidity and mortality in high-risk populations. Contemporary antifungal therapies rely heavily on three classes of antifungal drugs, and to date, no fungal vaccine is in clinical use for
Externí odkaz:
https://doaj.org/article/3b84f357422c490a9891b4b5cb08d249
Autor:
Whitney Rabacal, Finja Schweitzer, Heather M. Kling, Lizabeth Buzzelli, Emily Rayens, Karen A. Norris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionPneumocystis is a ubiquitous fungal pathogen that causes pneumonia (PCP) and pulmonary sequelae in HIV-infected individuals and other immunocompromised populations. With the success of anti-retroviral therapy for HIV-infected individuals
Externí odkaz:
https://doaj.org/article/9fcabf92075f4fc89f7d95a91d29657f
Publikováno v:
Vaccines, Vol 11, Iss 10, p 1521 (2023)
The development of efficient fungal vaccines is urgent for preventing life-threatening systemic fungal infections. In this study, we prepared a synthetic, cell-based fungal vaccine for preventing systemic fungal infections using synthetic biology tec
Externí odkaz:
https://doaj.org/article/ba662461c53142f3a2ff80e50a5f4397
Autor:
Maureen M. Hester, Lorena V. N. Oliveira, Ruiying Wang, Zhongming Mou, Diana Lourenco, Gary R. Ostroff, Charles A. Specht, Stuart M. Levitz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Meningitis due to the fungal pathogen Cryptococcus neoformans is estimated to cause nearly 200,000 deaths annually, mostly in resource-limited regions. We previously identified cryptococcal protein antigens which, when delivered in glucan particles,
Externí odkaz:
https://doaj.org/article/dd5f51e1e83046fa9dabdc899f222182
Autor:
Satya Ranjan Sahu, Swagata Bose, Manish Singh, Premlata Kumari, Abinash Dutta, Bhabasha Gyanadeep Utkalaja, Shraddheya Kumar Patel, Narottam Acharya
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Candidiasis is a mycosis caused by opportunistic Candida species. The occurrence of fungal infections has considerably increased in the last few years primarily due to an increase in the number of immune-suppressed individuals. Alarming bloodstream i
Externí odkaz:
https://doaj.org/article/3238cda19b4d4db5aeb3da941c744618
Autor:
Charles A. Specht, E. Jane Homan, Chrono K. Lee, Zhongming Mou, Christina L. Gomez, Maureen M. Hester, Ambily Abraham, Florentina Rus, Gary R. Ostroff, Stuart M. Levitz
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The high global burden of cryptococcosis has made development of a protective vaccine a public health priority. We previously demonstrated that a vaccine composed of recombinant Cryptococcus neoformans chitin deacetylase 2 (Cda2) delivered i
Externí odkaz:
https://doaj.org/article/1a6114f4299c4ca8a075e43864d1b9ee