Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Fung-Fang Wang"'
The cytoprotective function of p53 recently has been exploited as a therapeutic advantage for cancer prevention; agents activating the prosurvival activity of p53 are shown to prevent UV-induced damages. To explore the mechanisms of p53-mediated prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2f64d8dd2abf05373827c1e1014fde
https://doi.org/10.1158/0008-5472.c.6493925.v1
https://doi.org/10.1158/0008-5472.c.6493925.v1
Methods, Table, Figures 1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f59bcafbe14939b35f52f0460759e5
https://doi.org/10.1158/0008-5472.22363862
https://doi.org/10.1158/0008-5472.22363862
Autor:
Huan-Yu Lin, R. C. Lin, S. T. Lin, Hsin Chen Lee, R. H. Lai, Fung-Fang Wang, Chih Ching Lin, Mei Jung Wang, Jeou-Yuan Chen
Publikováno v:
Cell Death and Differentiation
Mitochondria are highly motile organelles that constantly undergo fission and fusion. Impairment of mitochondrial dynamics is associated with mitochondrial dysfunction and is frequently linked to the pathogenesis of neurodegenerative diseases and can
Publikováno v:
Cellular Signalling. 23:1816-1823
Polo-like kinase 1 (Plk1) plays key roles in many aspects of mitosis. We have previously shown that induction of p21 Waf1 by p53 is responsible for protection of cells against adriamycin-induced polyploidy formation and mitotic catastrophe. Here we s
Publikováno v:
Journal of Bone and Mineral Research. 25:2489-2503
Deficiency of the collagen receptor discoidin domain receptor tyrosine kinase (DDR2) in mice and humans results in dwarfism and short limbs, of which the mechanism remains unknown. Here we report that DDR2 is a key regulator of osteoblast differentia
Autor:
Yi Cheng Lin, Fung-Fang Wang
Publikováno v:
Cellular Signalling. 20:258-267
The p53 tumor suppressor responds to chemotherapeutic stress by triggering apoptosis or eliciting pro-survival pathway through arresting cell cycle progression for DNA damage repair. Here we examined the pro-survival activity of p53 on the adriamycin
Publikováno v:
Oncogene. 26:4928-4940
We have previously identified mouse DDA3 as a p53-inducible gene. To explore the functional role of DDA3, we screened a mouse brain cDNA library by the yeast two-hybrid assay, and identified the microtubule plus-end binding protein EB3 as a DDA3-inte
Autor:
Jeou-Yuan Chen, Chin-Chun Hung, Sheng-Ping L. Hwang, Chang Jen Huang, Fung-Fang Wang, Yi Chung Chen, Chih Ming Chou, Gen Der Chen
Publikováno v:
Biochemical and Biophysical Research Communications. 344:272-282
We expressed zebrafish p53 protein fused to GFP by a neuron-specific HuC promoter in zebrafish embryos. Instead of displaying neuronal expression patterns, p53-GFP was targeted to zebrafish YSL nuclei. This YSL targeting is p53 sequence-specific beca
Publikováno v:
Biomaterials. 27:1656-1664
CdSe/ZnS quantum dots (QDs) have recently been used as cell tracers for long term imaging of live cells. A number of studies indicate that introduction of quantum dots to cells have no apparent deleterious effects on the morphology or growth of cells
Publikováno v:
Cancer Research. 64:8736-8745
The cytoprotective function of p53 recently has been exploited as a therapeutic advantage for cancer prevention; agents activating the prosurvival activity of p53 are shown to prevent UV-induced damages. To explore the mechanisms of p53-mediated prot