Zobrazeno 1 - 10 of 202 pro vyhledávání: '"Fung Fuh Wong"'
1
Akademický článek
Protective Effects of One 2,4-Dihydro-3H-Pyrazol-3-one Derivative against Posterior Capsular Opacification by Regulation of TGF-β2/SMADs and Non-SMAD Signaling, Collagen I, and Fibronectin Proteins
Autor: Chun-Ching Shih, Chia-Yi Lee, Fung-Fuh Wong, Cheng-Hsiu Lin
Publikováno v: Current Issues in Molecular Biology, Vol 44, Iss 10, Pp 5048-5066 (2022)
Many elderly individuals frequently experience cataracts that interfere with vision. After cataract surgery, the left lens epithelial cell (LEC) exhibited fibrosis and posterior capsule opacification (PCO). Sometimes, there is a need for a second sur
Externí odkaz: https://doaj.org/article/ea8dfdb89ea44ba0b1a1b57f50ad76fd
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2
Akademický článek
Synthesis and evaluation of in vitro bioactivity for polysubstituted N-arylpyrazole derivatives
Autor: Naoto Uramaru, En-Chiuan Chang, Wan-Ping Yen, Mou-Yung Yeh, Shin-Hun Juang, Fung Fuh Wong
Publikováno v: Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 1908-1917 (2019)
New polysubstituted N-arylpyrazole derivatives were synthesized from N1-arylsydnone with acetylene and boronic acid, including 2-thiophenyl, 3-thiophenyl, 2-benzo[b]thiophenyl, or dibenzothiophenyl-4-boronic acid, via 1,3-dipolar cycloaddition and Su
Externí odkaz: https://doaj.org/article/ba4bcb352881465b8962b8a273148a61
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3
Akademický článek
Cyclopentadienyl Ruthenium(II) Complex-Mediated Oxidation of Benzylic and Allylic Alcohols to Corresponding Aldehydes
Autor: Ching-Yuh Chern, Ching-Chun Tseng, Rong-Hong Hsiao, Fung Fuh Wong, Yueh-Hsiung Kuo
Publikováno v: Heteroatom Chemistry, Vol 2019 (2019)
This work reports an efficient method for the oxidation reaction of aliphatic, aromatic allylic, and benzylic alcohols into aldehydes catalyzed by the cyclopentadienyl ruthenium(II) complex (RuCpCl(PPh3)2) with bubbled O2. Through further optimizing
Externí odkaz: https://doaj.org/article/ece78e5f4e484871a8f354d2c35a2a36
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4
Akademický článek
Structural Identification between Phthalazine-1,4-Diones and N-Aminophthalimides via Vilsmeier Reaction: Nitrogen Cyclization and Tautomerization Study
Autor: Cheng-Yen Chung, Ching-Chun Tseng, Sin-Min Li, Shuo-En Tsai, Hui-Yi Lin, Fung Fuh Wong
Publikováno v: Molecules, Vol 26, Iss 10, p 2907 (2021)
N-Aminophthalimides and phthalazine 1,4-diones were synthesized from isobenzofuran-1,3-dione, isoindoline-1,3-dione, furo [3,4-b] pyrazine-5,7-dione, or 1H-pyrrolo [3,4-c] pyridine-1,3-dione with monohydrate hydrazine to carry out the 5-exo or 6-endo
Externí odkaz: https://doaj.org/article/4662bdc194e3472289405670c65c091c
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6
Akademický článek
Selective Synthesis and Photoluminescence Study of Pyrazolopyridopyridazine Diones and N-Aminopyrazolopyrrolopyridine Diones
Autor: Ching-Chun Tseng, Cheng-Yen Chung, Shuo-En Tsai, Hiroyuki Takayama, Naoto Uramaru, Chin-Yu Lin, Fung Fuh Wong
Publikováno v: Molecules, Vol 25, Iss 10, p 2409 (2020)
The newly designed luminol structures of pyrazolopyridopyridazine diones and N-aminopyrazolopyrrolopyridine diones were synthesized from versatile 1,3-diaryfuropyrazolopyridine-6,8-diones, 1,3-diarylpyrazolopyrrolopyridine-6,8-diones, or 1,3-diaryl-7
Externí odkaz: https://doaj.org/article/9a41974d8e68480b8fc432c0c7a82150
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8
Bioactivity Study of Tricyclic and Tetracyclic Genipin Derivatives as Anti-inflammatory Agents
Autor: Sin-Min Li, Chia-Yin Chiang, Wei-Zheng Zeng, Cheng-Yen Chung, Ching-Chun Tseng, Yu-Pei Hu, Yu-Ching Lin, Guan-Jhong Huang, Ichiro Arai, Der-Yen Lee, Shuo-En Tsai, Fung Fuh Wong
Publikováno v: Bioorganic chemistry. 126
A series of genipin derivatives included tricyclic cyclopentaimidazopyridine, cyclopentapyridopyrimidine, octahydrocyclopentapyridodiazepine, and tetracyclic decahydrobenzoimidazocyclopentapyridine were synthesized and developed as anti-inflammatory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba5beefdb562173fd4854e630c4830a
https://pubmed.ncbi.nlm.nih.gov/35636127
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9
Synthesis of β-Amino Carbonyl 6-(Aminomethyl)- and 6-(Hydroxymethyl)pyrazolopyrimidines for DPP-4 Inhibition Study
Autor: Cheng-Yen Chung, Ching-Chun Tseng, Sin-Min Li, Wei-Zheng Zeng, Yu-Ching Lin, Yu-Pei Hu, Wen-Ping Jiang, Guan-Jhong Huang, Henry J. Tsai, Fung Fuh Wong
Publikováno v: Current medicinal chemistry.
Background: Type-2 diabetes is a chronic progressive metabolic disease resulting in severe vascular complications and mortality risk. Recently, DPP-4 inhibitors are conceived as a favorable class of agents for the treatment of type 2 diabetes due to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684154ebe6f439726dd2ed49b8e50851
https://pubmed.ncbi.nlm.nih.gov/35702778
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10
One-Pot Acid-Promoted Synthesis of 6-Aminopyrazolopyrimidines from 1H-Pyrazol-5-yl-N,N-dimethylformamidines or 5-Amino-1H-pyrazole-4-carbaldehydes with Cyanamide
Autor: Ching-Chun Tseng, Shuo-En Tsai, Sin-Min Li, Fung Fuh Wong
Publikováno v: The Journal of Organic Chemistry. 84:16157-16170
A convenient and efficient one-pot acid-promoted synthesis of 6-aminopyrazolo[3,4-d]pyrimidine has been developed by treatment of 1H-pyrazol-5-yl-N,N-dimethylformamidines or 5-amino-1H-pyrazole-4-carbaldehydes with cyanamide (NH2C≡N) in an acid-med
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67fb50998130bca478667c02ba126ba3
https://doi.org/10.1021/acs.joc.9b02653
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