Zobrazeno 1 - 10
of 1 144
pro vyhledávání: '"Fung, T."'
Autor:
Scott A. Williams, Fung T. Lay, Guneet K. Bindra, Suresh Banjara, Ivan K. H. Poon, Thanh Kha Phan, Marc Kvansakul, Mark D. Hulett
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Defensins are a class of host defence peptides that contribute to the immune system of eukaryotes. Here, the authors report the structure of saltwater crocodile defensin CpoBD13 and the mechanism of pH-dependent antifungal activity.
Externí odkaz:
https://doaj.org/article/34709b6a3e3f4e138fbe3e5c970854e2
Autor:
Fung, T. C.
The world’s coral reefs have been severely degraded over the past four decades and better management is urgently required to reverse this trend. Mathematical models are important tools for hypothesis and scenario testing, and are thus essential for
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625261
Publikováno v:
Philosophical Transactions: Biological Sciences, 2019 Oct . 374(1784), 1-8.
Externí odkaz:
https://www.jstor.org/stable/26784558
Autor:
Guneet K. Bindra, Scott A. Williams, Fung T. Lay, Amy A. Baxter, Ivan K. H. Poon, Mark D. Hulett, Thanh Kha Phan
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 264 (2022)
Defensins form an integral part of the cationic host defence peptide (HDP) family, a key component of innate immunity. Apart from their antimicrobial and immunomodulatory activities, many HDPs exert multifaceted effects on tumour cells, notably direc
Externí odkaz:
https://doaj.org/article/57fca984987f452bbb277fd4384d45b4
Autor:
Michael Järvå, Fung T. Lay, Thanh Kha Phan, Cassandra Humble, Ivan K. H. Poon, Mark R. Bleackley, Marilyn A. Anderson, Mark D. Hulett, Marc Kvansakul
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Defensins are cationic antimicrobial peptides that permeabilize membranes of pathogens presumably via the assembly of defensin–lipid oligomers. Here authors provide evidence for this by solving the crystal structure of a plant defensin in an oligom
Externí odkaz:
https://doaj.org/article/92a541026fb04b6bafa9a12c66ec4740
Akademický článek
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Akademický článek
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Autor:
Georgia K. Atkin-Smith, Mark A. Miles, Rochelle Tixeira, Fung T. Lay, Mubing Duan, Christine J. Hawkins, Thanh Kha Phan, Stephanie Paone, Suresh Mathivanan, Mark D. Hulett, Weisan Chen, Ivan K.H. Poon
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1821-1831.e3 (2019)
Summary: Billions of cells undergo apoptosis daily and often fragment into small, membrane-bound extracellular vesicles termed apoptotic bodies (ApoBDs). We demonstrate that apoptotic monocytes undergo a highly coordinated disassembly process and for
Externí odkaz:
https://doaj.org/article/4a9537e656714abf901006e93d28905c
Autor:
Bomai K. Kerenga, James A. McKenna, Peta J. Harvey, Pedro Quimbar, Donovan Garcia-Ceron, Fung T. Lay, Thanh Kha Phan, Prem K. Veneer, Shaily Vasa, Kathy Parisi, Thomas M. A. Shafee, Nicole L. van der Weerden, Mark D. Hulett, David J. Craik, Marilyn A. Anderson, Mark R. Bleackley
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Pathogenic microbes are developing resistance to established antibiotics, making the development of novel antimicrobial molecules paramount. One major resource for discovery of antimicrobials is the arsenal of innate immunity molecules that are part
Externí odkaz:
https://doaj.org/article/405411b58d674762ae65be780f160ed3
Autor:
Kvansakul, Marc, Lay, Fung T., Adda, Christopher G., Veneer, Prem K., Baxter, Amy A., Phan, Thanh Kha, Poon, Ivan K. H., Hulett, Mark D.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Oct 01. 113(40), 11202-11207.
Externí odkaz:
https://www.jstor.org/stable/26471925