Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Funda, Korkmaz"'
Autor:
Vitaly Ryu, Anisa Azatovna Gumerova, Ronit Witztum, Funda Korkmaz, Liam Cullen, Hasni Kannangara, Ofer Moldavski, Orly Barak, Daria Lizneva, Ki A Goosens, Sarah Stanley, Se-Min Kim, Tony Yuen, Mone Zaidi
Publikováno v:
eLife, Vol 13 (2024)
There is clear evidence that the sympathetic nervous system (SNS) mediates bone metabolism. Histological studies show abundant SNS innervation of the periosteum and bone marrow–these nerves consist of noradrenergic fibers that immunostain for tyros
Externí odkaz:
https://doaj.org/article/a8a653d789f845e8876a995a110d6788
Publikováno v:
Osteoporosis and Sarcopenia, Vol 9, Iss 4, Pp 115-120 (2023)
Hypophosphatasia (HPP), also called Rathbun disease, is a rare genetic disorder that is caused by the loss-of-function mutation in the ALPL gene encoding tissue non-specific alkaline phosphatase. Doctor Rathbun first described the case of a 3-week-ol
Externí odkaz:
https://doaj.org/article/16c06350067c4feaabe7803a5d555ffa
Publikováno v:
Endocrinology and Metabolism, Vol 37, Iss 5, Pp 719-731 (2022)
Over the past years, pituitary hormones and their receptors have been shown to have non-traditional actions that allow them to bypass the hypothalamus-pituitary-effector glands axis. Bone cells—osteoblasts and osteoclasts—express receptors for gr
Externí odkaz:
https://doaj.org/article/693d24aa45834deebdcab911f99fd801
Autor:
Satish Rojekar, Anusha R Pallapati, Judit Gimenez-Roig, Funda Korkmaz, Farhath Sultana, Damini Sant, Clement M Haeck, Anne Macdonald, Se-Min Kim, Clifford J Rosen, Orly Barak, Marcia Meseck, John Caminis, Daria Lizneva, Tony Yuen, Mone Zaidi
Publikováno v:
eLife, Vol 12 (2023)
Highly concentrated antibody formulations are oftentimes required for subcutaneous, self-administered biologics. Here, we report the development of a unique formulation for our first-in-class FSH-blocking humanized antibody, MS-Hu6, which we propose
Externí odkaz:
https://doaj.org/article/dbfcd21d71574f6ca1d659719f942a73
Autor:
Mone Zaidi, Se-Min Kim, Mehr Mathew, Funda Korkmaz, Farhath Sultana, Sari Miyashita, Anisa Azatovna Gumerova, Tal Frolinger, Ofer Moldavski, Orly Barak, Anusha Pallapati, Satish Rojekar, John Caminis, Yelena Ginzburg, Vitaly Ryu, Terry F Davies, Daria Lizneva, Clifford J Rosen, Tony Yuen
Publikováno v:
eLife, Vol 12 (2023)
The past decade has seen significant advances in our understanding of skeletal homeostasis and the mechanisms that mediate the loss of bone integrity in disease. Recent breakthroughs have arisen mainly from identifying disease-causing mutations and m
Externí odkaz:
https://doaj.org/article/5801ddfa32fa4f7bbd7303df9b74e5ce
Autor:
Sakshi Gera, Tan-Chun Kuo, Anisa Azatovna Gumerova, Funda Korkmaz, Damini Sant, Victoria DeMambro, Karthyayani Sudha, Ashley Padilla, Geoffrey Prevot, Jazz Munitz, Abraham Teunissen, Mandy MT van Leent, Tomas GJM Post, Jessica C Fernandes, Jessica Netto, Farhath Sultana, Eleanor Shelly, Satish Rojekar, Pushkar Kumar, Liam Cullen, Jiya Chatterjee, Anusha Pallapati, Sari Miyashita, Hasni Kannangara, Megha Bhongade, Puja Sengupta, Kseniia Ievleva, Valeriia Muradova, Rogerio Batista, Cemre Robinson, Anne Macdonald, Susan Hutchison, Mansi Saxena, Marcia Meseck, John Caminis, Jameel Iqbal, Maria I New, Vitaly Ryu, Se-Min Kim, Jay J Cao, Neeha Zaidi, Zahi A Fayad, Daria Lizneva, Clifford J Rosen, Tony Yuen, Mone Zaidi
Publikováno v:
eLife, Vol 11 (2022)
Pharmacological and genetic studies over the past decade have established the follicle-stimulating hormone (FSH) as an actionable target for diseases affecting millions, namely osteoporosis, obesity, and Alzheimer’s disease. Blocking FSH action pre
Externí odkaz:
https://doaj.org/article/0b0425ac3b2842fcad3a4a75380448c1
Autor:
Vitaly Ryu, Anisa Gumerova, Funda Korkmaz, Seong Su Kang, Pavel Katsel, Sari Miyashita, Hasni Kannangara, Liam Cullen, Pokman Chan, TanChun Kuo, Ashley Padilla, Farhath Sultana, Soleil A Wizman, Natan Kramskiy, Samir Zaidi, Se-Min Kim, Maria I New, Clifford J Rosen, Ki A Goosens, Tal Frolinger, Vahram Haroutunian, Keqiang Ye, Daria Lizneva, Terry F Davies, Tony Yuen, Mone Zaidi
Publikováno v:
eLife, Vol 11 (2022)
There is increasing evidence that anterior pituitary hormones, traditionally thought to have unitary functions in regulating single endocrine targets, act on multiple somatic tissues, such as bone, fat, and liver. There is also emerging evidence for
Externí odkaz:
https://doaj.org/article/b3abe24a02a0498d998322980e6ccd74
Autor:
Damini Sant, Satish Rojekar, Sakshi Gera, Anusha R. Pallapati, Judit Gimenez‐Roig, Tan‐Chun Kuo, Ashley Padilla, Funda Korkmaz, Liam Cullen, Jiya Chatterjee, Eleanor Shelly, Marcia Meseck, Sari Miyashita, Anne Macdonald, Farhath Sultana, Orly Barak, Vitaly Ryu, Se‐Min Kim, Cemre Robinson, Clifford J. Rosen, John Caminis, Daria Lizneva, Shozeb Haider, Tony Yuen, Mone Zaidi
Publikováno v:
Annals of the New York Academy of Sciences. 1521:67-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77225ee79467ad03dc80b53b2796e625
https://doi.org/10.1111/nyas.14952
https://doi.org/10.1111/nyas.14952
Autor:
Hasni Kannangara, Liam Cullen, Sari Miyashita, Funda Korkmaz, Anne Macdonald, Anisa Gumerova, Ronit Witztum, Ofer Moldavski, Steven Sims, Jocoll Burgess, Tal Frolinger, Rauf Latif, Yelena Ginzburg, Daria Lizneva, Ki Goosens, Terry F. Davies, Tony Yuen, Mone Zaidi, Vitaly Ryu
Publikováno v:
Annals of the New York Academy of Sciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0a1d3fdf05b3c59e458832c119192a
https://doi.org/10.1111/nyas.15009
https://doi.org/10.1111/nyas.15009
Autor:
Jing Xiong, Seong Su Kang, Zhihao Wang, Xia Liu, Tan-Chun Kuo, Funda Korkmaz, Ashley Padilla, Sari Miyashita, Pokman Chan, Zhaohui Zhang, Pavel Katsel, Jocoll Burgess, Anisa Gumerova, Kseniia Ievleva, Damini Sant, Shan-Ping Yu, Valeriia Muradova, Tal Frolinger, Daria Lizneva, Jameel Iqbal, Ki A. Goosens, Sakshi Gera, Clifford J. Rosen, Vahram Haroutunian, Vitaly Ryu, Tony Yuen, Mone Zaidi, Keqiang Ye
Publikováno v:
Nature. 603:470-476
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09cad8182333e9e91c4a98055f10e0ec
https://doi.org/10.1038/s41586-022-04463-0
https://doi.org/10.1038/s41586-022-04463-0