Deuterated water imaging of the rat brain following metabolism of [ 2 H 7 ]glucose

Autor: Rohit Mahar, Anthony G. Giacalone, Huadong Zeng, Thomas H. Mareci, Matthew E. Merritt, Mukundan Ragavan

Publikováno v: Magnetic Resonance in Medicine. 85:3049-3059

Purpose To determine whether deuterated water (HDO) generated from the metabolism of [2 H7 ]glucose is a sensitive biomarker of cerebral glycolysis and oxidative flux. Methods A bolus of [2 H7 ]glucose was injected through the tail vein at 1.95 g/kg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ffbbfbeca9ae0211ffa1f3bda9393022
https://doi.org/10.1002/mrm.28700

Reproducibility of 7‐T brain spectroscopy using an ultrashort echo time STimulated Echo Acquisition Mode sequence and automated voxel repositioning

Autor: Meredith A. Reid, Martha R. Forloines, Nouha Salibi

Publikováno v: NMR Biomed

Establishing the reproducibility of brain MRS is important for clinical studies so that researchers can evaluate changes in metabolites due to treatment or the course of a disease and better understand the brain in healthy and disordered states. Prio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c461dfaecdc5cffd7119773af191d04
https://doi.org/10.1002/nbm.4631

High-resolution metabolic mapping of gliomas via patch-based super-resolution magnetic resonance spectroscopic imaging at 7T

Autor: Elisabeth Springer, Dirk Smeets, Julia Furtner, Gilbert Hangel, Saurabh Jain, Georg Widhalm, Thomas Roetzer, Matthias Preusser, Barbara Kiesel, Wolfgang Bogner, Siegfried Trattnig, Diana M. Sima, Eva Heckova, Michal Považan, Stephan Gruber, Bernhard Strasser

Publikováno v: Neuroimage

Objectives To demonstrate the feasibility of 7 T magnetic resonance spectroscopic imaging (MRSI), combined with patch-based super-resolution (PBSR) reconstruction, for high-resolution multi-metabolite mapping of gliomas. Materials and methods Ten pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746eca923a255eb853ae3faa3e9b06bf
https://doi.org/10.1016/j.neuroimage.2019.02.023

Implications of neurovascular uncoupling in functional magnetic resonance imaging (fMRI) of brain tumors

Autor: Nitish V. Thakor, Jay J. Pillai, Janaka Senarathna, Darian Hadjiabadi, Rebecca W. Pak, Shruti Agarwal, Arvind P. Pathak

Publikováno v: Journal of Cerebral Blood Flow & Metabolism. 37:3475-3487

Functional magnetic resonance imaging (fMRI) serves as a critical tool for presurgical mapping of eloquent cortex and changes in neurological function in patients diagnosed with brain tumors. However, the blood-oxygen-level-dependent (BOLD) contrast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773a061802f07a65f54d1fabb0cff54c
https://doi.org/10.1177/0271678x17707398

Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes

Autor: Jesper Karmisholt, Anne Juhl, Poul Erik Jakobsen, Birgitte Brock, Henrik Vorum, Asbjørn Mohr Drewes, Jens Brøndum Frøkjær, Carl Uggerhøj Andersen, Christina Brock, Tine Maria Hansen

Publikováno v: Hansen, T M, Brock, B, Juhl, A, Drewes, A M, Vorum, H, Andersen, C U, Jakobsen, P E, Karmisholt, J S, Frøkjær, J B & Brock, C 2019, ' Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes ', Journal of Diabetes and its Complications, vol. 33, no. 4, pp. 323-328 . https://doi.org/10.1016/j.jdiacomp.2018.12.016
Hansen, T M, Brock, B, Juhl, A, Drewes, A M, Vorum, H, Andersen, C U, Jakobsen, P E, Karmisholt, J, Frøkjær, J B & Brock, C 2019, ' Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes ', Journal of Diabetes and its Complications, vol. 33, no. 4, pp. 323-328 . https://doi.org/10.1016/j.jdiacomp.2018.12.016
Hansen, T M, Brock, B, Juhl, A, Drewes, A M, Vorum, H, Andersen, C U, Jakobsen, P E, Karmisholt, J, Frokjaer, J B & Brock, C 2019, ' Brain spectroscopy reveals that N-acetylaspartate is associated to peripheral sensorimotor neuropathy in type 1 diabetes ', Journal of Diabetes and its Complications, vol. 33, no. 4, pp. 323-328 . https://doi.org/10.1016/j.jdiacomp.2018.12.016

Aims: Emerging evidence shows, that distal symmetric peripheral neuropathy (DSPN) also involves alterations in the central nervous system. Hence, the aims were to investigate brain metabolites in white matter of adults with diabetes and DSPN, and to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f6c92b9971c52040febe7698bc9a66
https://pure.au.dk/portal/da/publications/brain-spectroscopy-reveals-that-nacetylaspartate-is-associated-to-peripheral-sensorimotor-neuropathy-in-type-1-diabetes(fece78f8-6469-4161-8d02-5a4d981ff8fe).html