Reduced expression of L-selectin in T-cells correlates with relative lymphocyte increase in patients with RRMS treated with natalizumab - functional implication towards PML risk

Autor: Theano Tatsi, Anna Kalogera-Fountzila, Lemonia Skoura, Vasiliki Tsavdaridou, Eleni Polyzoidou, Dimitrios Parissis, Eleni Grigoriadou, Virginia Giantzi, Panagiotis Ioannidis, Theodoros Karapanayotides, Roza Lagoudaki, Nikolaos Grigoriadis, Ioannis Nikolaidis, Theodora Afrantou, Pamela Melo, Marina Boziki, Sofia Zoidou, Georgios C. Papadopoulos, Evdoxia Gounari, Nikolaos Mandoras, Christos Bakirtzis, Sygkliti-Henrietta Pelidou

Publikováno v: Neurological Research. 42:209-221

Objectives: Natalizumab (NTZ), a treatment indicated for patients with highly active Relapsing – Remitting Multiple Sclerosis (RRMS), is known to induce increased relative frequency of lymphocytes. Progressive Multifocal Leukoencephalitis (PML) is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0932e073456ab527207e5879a3a915
https://doi.org/10.1080/01616412.2020.1722913

Hypermobile Ehlers-Danlos syndrome: A review and a critical appraisal of published genetic research to date

Autor: Melissa M. Formosa, Kirsty Scicluna, Rosienne Farrugia, Isabella Borg

Publikováno v: Clinical geneticsREFERENCES. 101(1)

The Ehlers-Danlos syndromes (EDS) are a collection of rare hereditary connective tissue disorders with heterogeneous phenotypes, usually diagnosed following clinical examination and confirmatory genetic testing. Diagnosis of the commonest subtype, hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c49986815ce223da8bace25280e8702
https://pubmed.ncbi.nlm.nih.gov/34219226

Combining Electrostimulation With Fiber Tracking to Stratify the Inferior Fronto-Occipital Fasciculus

Autor: Alexandre Roux, Anne-Laure Lemaitre, Jeremy Deverdun, Sam Ng, Hugues Duffau, Guillaume Herbet

Publikováno v: Frontiers in Neuroscience
Frontiers in Neuroscience, Frontiers, 2021, 15, pp.683348. ⟨10.3389/fnins.2021.683348⟩
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience, 2021, 15, pp.683348. ⟨10.3389/fnins.2021.683348⟩

International audience; The inferior fronto-occipital fasciculus (IFOF) is one of the longest association fiber tracts of the brain. According to the most recent anatomical studies, it may be formed by several layers, suggesting a role in multiple co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ad56f7ace59a40da687e9d9a618ec5d
http://europepmc.org/articles/PMC8172990

Carbon dioxide and bicarbonate accumulation in caiman erythrocytes during diving

Autor: Naim M. Bautista, Christian Damsgaard, Angela Fago, Tobias Wang

Publikováno v: Bautista, N M, Damsgaard, C, Fago, A & Wang, T 2021, ' Carbon dioxide and bicarbonate accumulation in caiman erythrocytes during diving ', Journal of Experimental Biology, vol. 224, no. 9, 242435 . https://doi.org/10.1242/jeb.242435

The ability of crocodilian haemoglobins to bind HCO3– has been appreciated for more than half a century, but the functional implication of this exceptional mechanism has not previously been assessed in vivo. Therefore, the goal of the present study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8ec6fa19e9e09c09393c31f96ed8e0
https://pubmed.ncbi.nlm.nih.gov/33771914

Structural plasticity of BCL-2 family proteins and its functional implication in apoptosis

Autor: Minjoo Choi

Dysregulated apoptosis has been implicated in the development of several diseases including cancer and neurodegenerative diseases. Bcl-2 family proteins regulate mitochondrial apoptosis through homo- and hetero-dimerization between pro- and anti-apop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d8c97cd418d62dd49756618c81ca1b
https://doi.org/10.32657/10356/73522