Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Fumiyo Kubo"'
Autor:
Shugo Sasaki, Hirotaka Watada, Maureen Gannon, Mitsuyoshi Takahara, Hideaki Kaneto, Taka-aki Matsuoka, Takeshi Miyatsuka, Yuichi Yamamoto, Fumiyo Kubo, Iichiro Shimomura, Naoki Shimo
Publikováno v:
Biochemical and Biophysical Research Communications. 471:68-74
Glucagon-like peptide 1 (GLP-1) has been shown to play important roles in maintaining β-cell functions, such as insulin secretion and proliferation. While expression levels of GLP-1 receptor (Glp1r) are compromised in the islets of diabetic rodents,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83002cd38d4b95395dba4b12cb355f1
https://doi.org/10.1016/j.bbrc.2016.01.177
https://doi.org/10.1016/j.bbrc.2016.01.177
Autor:
Takeshi Miyatsuka, Taka-aki Matsuoka, Shugo Sasaki, Michael S. German, Fumiyo Kubo, Iichiro Shimomura, Hirotaka Watada, Manami Hara
Publikováno v:
Diabetes
Although numerous studies have uncovered the molecular mechanisms regulating pancreas development, it remains to be clarified how β-cells arise from progenitors and how recently specified β-cells are different from preexisting β-cells. To address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7b54ae65e153403d8041da1f109d89
https://doi.org/10.2337/db13-1312
https://doi.org/10.2337/db13-1312
Autor:
Toyoko Naka, Munehide Matsuhisa, Hideaki Kaneto, Akio Kuroda, Tetsuyuki Yasuda, Iichiro Shimomura, Mayumi Tsuji, Kazuyuki Miyashita, Shugo Sasaki, Naoto Katakami, Keiko Fujisawa, Fumiyo Kubo, Ryuuichi Kasami
Publikováno v:
Journal of Diabetes Investigation
Aims/Introduction The aim of the present study was to examine the short- and long-term effect of sitagliptin on glucose tolerance after near normalization of glycemic control with insulin in poorly controlled type 2 diabetic patients. Materials and M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4102582626fe223910377061c0bb82e8
https://doi.org/10.1111/jdi.12176
https://doi.org/10.1111/jdi.12176
Autor:
Akemi Ono, Kazutomi Yoshiuchi, Koji Tomita, Hiroshi Maegawa, Ken’ya Sakamoto, Fumiyo Kubo, Munehide Matsuhisa, Hiromu Nakajima, Hideaki Kaneto, Toshiyuki Sato, Keisuke Kosugi, Kazuhiko Sakaguchi, Atsunori Kashiwagi
Publikováno v:
Journal of Diabetes Investigation
Aims/Introduction To realize the effectiveness of a novel system for measuring glucose area under the curve (AUC) using minimally invasive interstitial fluid extraction technology (MIET), outpatients undergoing oral glucose tolerance tests (OGTT) wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0574efd1f6ae1b151f50b9262ea20c7c
https://doi.org/10.1111/jdi.12096
https://doi.org/10.1111/jdi.12096
Autor:
Fumie Sakamoto, Keiko Fujisawa, Mitsuyoshi Takahara, Yoko Irie, Iichiro Shimomura, Toyoko Naka, Naoto Katakami, Taka-aki Matsuoka, Fumiyo Kubo, Kazuyuki Miyashita, Tetsuyuki Yasuda, Hideaki Kaneto
Publikováno v:
Atherosclerosis. 227:425-428
It is still controversial whether circulating soluble form of receptor for AGE (sRAGE) is associated with atherosclerosis in diabetic patients. In this study, we enrolled 276 Japanese type 2 diabetic subjects without history of cardiovascular disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04300c618a49bdf8ab121ca7caf81019
https://doi.org/10.1016/j.atherosclerosis.2013.01.016
https://doi.org/10.1016/j.atherosclerosis.2013.01.016
Autor:
Hirotaka Watada, Takeshi Miyatsuka, Hideaki Kaneto, Satomi Takebe, Taka-aki Matsuoka, Iichiro Shimomura, Yuichi Yamamoto, Kazuyuki Miyashita, Fumiyo Kubo, Shugo Sasaki, Naoki Shimo
Publikováno v:
Biochemical and biophysical research communications. 483(1)
Pdx1, a β-cell-specific transcription factor, has been shown to play a crucial role in maintaining β-cell function through transactivation of β-cell-related genes. In addition, it has been reported that the expression levels of Pdx1 are compromise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6401b6e2ad53862a39c3049227c4aa
https://pubmed.ncbi.nlm.nih.gov/28017717
https://pubmed.ncbi.nlm.nih.gov/28017717
Autor:
Kazutomi Yoshiuchi, Takashi Katsura, Ken’ya Sakamoto, Mitsuyoshi Takahara, Naoto Katakami, Keisuke Kosugi, Hideaki Kaneto, Yoshimitsu Yamasaki, Yoko Irie, Fumiyo Kubo, Iichiro Shimomura
Publikováno v:
Diabetes Care
OBJECTIVE The aim of this study is to evaluate whether noninvasive ultrasonic tissue characterization of carotid plaque using integrated backscatter (IBS) analysis can be a predictor of future cardiovascular events (CVE) in asymptomatic type 2 diabet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c2a1b8d0398c8789e159c68ace7101
https://doi.org/10.2337/dc12-0331
https://doi.org/10.2337/dc12-0331
Autor:
Takahiro Okusu, Fumiyo Kubo, Yuichi Yamamoto, Ken’ya Sakamoto, Toshikazu Kashiyama, Takashi Katura, Yasunori Ueda, Naoto Katakami, Yutaka Umayahara, Hideaki Kaneto, Keisuke Kosugi, Yoko Irie
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 18:337-344
Aims: Carotid atherosclerosis assessed by ultrasound is an established surrogate marker for systemic atherosclerosis. This study aimed to evaluate the association between coronary artery stenosis assessed by coronary computed tomography angiography (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79307afc97bb271ffeae789d546fd80
https://doi.org/10.5551/jat.6049
https://doi.org/10.5551/jat.6049
Autor:
Hideaki Kaneto, Keisuke Kosugi, Kazutomi Yoshiuchi, Yozo Kanamaru, Takashi Katsura, Yoko Irie, Ihoko Nakashoutani, Iichiro Shimomura, Naoto Katakami, Fumiyo Kubo, Takahiro Okusu, Yuichi Yamamoto, Ken’ya Sakamoto
Publikováno v:
Diabetes technologytherapeutics. 17(6)
Cholesterol absorption has been suggested to be an independent risk factor for cerebral and cardiovascular events. We studied the clinical efficacy of ezetimibe in Japanese patients with type 2 diabetes mellitus complicated by dyslipidemia, in whom i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c358de9ec39a74a6888762e01439ca5
https://pubmed.ncbi.nlm.nih.gov/25714444
https://pubmed.ncbi.nlm.nih.gov/25714444
Autor:
Taka-aki Matsuoka, Mitsuyoshi Takahara, Fumiyo Kubo, Naoki Shimo, Tetsuyuki Yasuda, Iichiro Shimomura
Publikováno v:
Acta Diabetologica. 53:861-862
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4898c62a08da4b1a8bd4a8830610dc
https://doi.org/10.1007/s00592-016-0849-x
https://doi.org/10.1007/s00592-016-0849-x