Výsledky vyhledávání - "Fumiyo Fukuya"

A Novel αvβ3 Integrin Antagonist Suppresses Neointima Formation for More Than 4 Weeks After Balloon Injury in Rats

Autor: Tomoko Kitano, Toshiya Morie, Mitsue Notake, Yayoi Honda, Seiji Iwama, Yuji Sato, Fumiyo Fukuya

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 25:1376-1382

Objectives— We performed a detailed kinetic analysis in a rat balloon injury model to clarify the essential roles of αvβ3 integrin and endothelial cell (EC) regeneration in neointima formation. Using this model, we evaluated the antistenotic effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a93c1618f559ae3eb8892ae21be828
https://doi.org/10.1161/01.atv.0000168902.18672.2f

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Discovery of a potent and selective alpha v beta 3 integrin antagonist with strong inhibitory activity against neointima formation in rat balloon injury model

Autor: Mitsue Notake, Toshiya Morie, Seiji Iwama, Tomoko Kitano, Yuji Sato, Yayoi Honda, Fumiyo Fukuya

Publikováno v: Bioorganicmedicinal chemistry letters. 14(10)

A new series of phenylpiperazine-based derivatives with strong antagonistic activity for alpha v beta 3 integrin were synthesized. Of these derivatives, the fluorine-substituted compound 8 showed strong inhibitory activity and high selectivity for al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13bf1e2575e087c381030222adcf862
https://pubmed.ncbi.nlm.nih.gov/15109653

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Changes in autonomic activity and baroreflex sensitivity with the hypertension process and age in rats

Autor: Toshio Ogihara, Shinya Nagata, Fumiyo Fukuya, Jitsuo Higaki, Ryuji Nagai, Hiromi Rakugi

Publikováno v: Clinical and experimental pharmacologyphysiology. 30(5-6)

1. Autonomic activity and baroreflex sensitivity (BRS) were compared in age-matched conscious groups of Wistar Kyoto (WKY) rats, spontaneously hypertensive rats (SHR) and stroke-prone spontaneously hypertensive rats (SHRSP). 2. Male WKY rats, SHR and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b822b5c24823378c1ef339f1362fa89
https://pubmed.ncbi.nlm.nih.gov/12859436

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The effects of the adrenergic transmission change on low frequency (LF) and very low frequency (VLF) components of heart rate and blood pressure fluctuation in conscious rats. -Studies with wavelet analysis

Autor: Shinya Nagata, Ryuji Nagai, Fumiyo Fukuya, Kenji Kouchi, Masanobu Komiya

Publikováno v: Japanese Journal of Pharmacology. 82:217

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00bcc6ada327bfa89f00ca74b6b6d597
https://doi.org/10.1016/s0021-5198(19)48332-7

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The novel anticonvulsant zonisamide prevents dopaninergic neurodegeneration induced by MPTP

Autor: Yoshiaki Ochi, Fumiyo Fukuya, Hideto Noguchi, Kazuo Okimoto, Hitoshi Kohayakawa, Kanoo Hosoki, Yoshinobu Masuda

Publikováno v: Japanese Journal of Pharmacology. 76:119

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dd3a5c29baa9a0ceae710ff1a12c1d4
https://doi.org/10.1016/s0021-5198(19)40594-5

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DU-1777, a novel ACE inhibitor, possibly involves an ATP - sensitive K+-channels-related mechanism in its antihypertensive and cough-suppressant effects

Autor: Kunihiko Takeyama, Fumiyo Fukuya, Tadahiko Karasawa, Kanoo Hosoki, Shinya Naoata

Publikováno v: Japanese Journal of Pharmacology. 58:393

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3098c618f911de8286ffe76a00cb78b
https://doi.org/10.1016/s0021-5198(19)49673-x

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