Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fumiya Ishizuka"'
Autor:
Shigeharu Muto, Ayako Furuhama, Mika Yamamoto, Yasuteru Otagiri, Naoki Koyama, Seiji Hitaoka, Yusuke Nagato, Hirofumi Ouchi, Masahiro Ogawa, Kisako Shikano, Katsuya Yamada, Satoshi Ono, Minami Hoki, Fumiya Ishizuka, Soichiro Hagio, Chiaki Takeshita, Hisayoshi Omori, Kiyohiro Hashimoto, Satsuki Chikura, Masamitsu Honma, Kei-ichi Sugiyama, Masayuki Mishima
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-10 (2024)
Abstract Background Primary aromatic amines (PAAs) present significant challenges in the prediction of mutagenicity using current standard quantitative structure activity relationship (QSAR) systems, which are knowledge-based and statistics-based, be
Externí odkaz:
https://doaj.org/article/3b431e34936344f28473dfc085ece5fa
Autor:
Shinsuke Nakamura, Hideaki Hara, Masamitsu Shimazawa, Kazuhiro Tsuruma, Naofumi Umigai, Fumiya Ishizuka, Hiromi Ogishima
Publikováno v:
European Journal of Pharmacology. 703:1-10
Crocetin, an aglycone of crocin, is found both in the saffron crocus (Crocus starus L.) and in gardenia fruit (Gardenia jasminoides Ellis). We evaluated the protective effects of crocetin against the retinal ischemia induced by 5 h unilateral ligatio
Autor:
Hiromi Ogishima, Yusuke Egashira, Kazuhiro Tsuruma, Fumiya Ishizuka, Shinsuke Nakamura, Hideaki Hara, Masamitsu Shimazawa
Publikováno v:
Pharmacology Research & Perspectives
Cilostazol is a specific inhibitor of phosphodiesterase III and is widely used to treat ischemic symptoms of peripheral vascular disease. We evaluated the protective effects of cilostazol in a murine model of ocular ischemic syndrome in which retinal
Autor:
I. Ikegaki, Hideaki Hara, Keisuke Mishiro, Toru Iwama, Mitsunori Ishiguro, K. Kawasaki, Yusuke Egashira, Shinichi Yoshimura, Kazuhiro Tsuruma, Yukiya Suzuki, Masamitsu Shimazawa, Fumiya Ishizuka
Publikováno v:
Neuroscience. 220
Thrombolysis with tissue plasminogen activator (tPA) is the only FDA-approved therapy for acute ischemic stroke. However, hemorrhagic transformation, neurotoxicity, and a short treatment time window comprise major limitations for thrombolytic therapy
Autor:
Hiroyuki Tanaka, Naoki Inagaki, Masamitsu Shimazawa, Fumiya Ishizuka, Kazuhiro Tsuruma, Hideaki Hara, Yuki Inoue, Hiromi Ogishima, Yusuke Nakano, Shinsuke Nakamura
Publikováno v:
Investigative Opthalmology & Visual Science. 54:5807
Purpose Inflammatory response has a critical role in neuronal damage after retinal ischemia-reperfusion (I/R) injury, and is regulated tightly by the toll-like receptor (TLR) 4. This study aimed to determine whether TLR4 is involved with injury in an
Autor:
Fumiya Ishizuka, Masamitsu Shimazawa, Kazuhiro Tsuruma, Tomohiro Nakanishi, Shunsuke Imai, Hiromi Ogishima, Hideaki Hara, Shinsuke Nakamura, Mamoru Kakino
Publikováno v:
Investigative Opthalmology & Visual Science. 52:9710
Purpose This study aimed to characterize the functional and morphologic changes in a murine model of ocular ischemic disease caused by vascular occlusion. Methods Retinal ischemia was induced by unilateral ligation of the pterygopalatine artery (PPA)
Autor:
Tomomi Masuda1, Masamitsu Shimazawa1, Fumiya Ishizuka1, Shinsuke Nakamura1, Kazuhiro Tsuruma1, Hideaki Hara1 hidehara@gifu-pu.ac.jp
Publikováno v:
European Journal of Pharmacology. Sep2014, Vol. 738, p74-82. 9p.