Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Fumitaka Ushikubi"'
Autor:
Fumiaki Kojima, Hiroki Sekiya, Yuka Hioki, Hitoshi Kashiwagi, Makoto Kubo, Masaki Nakamura, Shotaro Maehana, Yoshitaka Imamichi, Koh-ichi Yuhki, Fumitaka Ushikubi, Hidero Kitasato, Takafumi Ichikawa
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-24 (2022)
Abstract Background Microsomal prostaglandin E synthase-1 (mPGES-1) is a key enzyme that acts downstream of cyclooxygenase and plays a major role in inflammation by converting prostaglandin (PG) H2 to PGE2. The present study investigated the effect o
Externí odkaz:
https://doaj.org/article/78235e4fb4724385b2106c700040599e
Autor:
Takayasu Kanno, Naoki Nakagawa, Tatsuya Aonuma, Jun-ichi Kawabe, Koh-ichi Yuhki, Naofumi Takehara, Naoyuki Hasebe, Fumitaka Ushikubi
Publikováno v:
Heart and Vessels. 38:606-613
Ischemic preconditioning (IPC) describes a phenomenon wherein brief ischemia of the heart induces a potent cardioprotective mechanism against succeeding ischemic insult. Cyclooxygenase-2 (COX-2), a rate-limiting enzyme in prostanoid biosynthesis, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f54d5938ba76b84e6fb1979a715b5d5
https://doi.org/10.1007/s00380-022-02219-4
https://doi.org/10.1007/s00380-022-02219-4
Autor:
Yoshitaka Imamichi, Toshio Sekiguchi, Takeshi Kitano, Takashi Kajitani, Reiko Okada, Yoshihiko Inaoka, Kaoru Miyamoto, Junsuke Uwada, Satoru Takahashi, Takahiro Nemoto, Asuka Mano, Md Rafiqul Islam Khan, Md Tariqul Islam, Koh-ichi Yuhki, Hitoshi Kashiwagi, Fumitaka Ushikubi, Nobuo Suzuki, Takanobu Taniguchi, Takashi Yazawa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Diethylstilbestrol (DES), a strong estrogenic compound, is well-known to affect the reproductive system. In this study, we investigated the effects of DES administration on gonadotropin levels and ovarian steroidogenesis in prepubertal rats.
Externí odkaz:
https://doaj.org/article/4a1dd609111b43a18d7f939cc20bbcdb
Autor:
Takayasu, Kanno, Naoki, Nakagawa, Tatsuya, Aonuma, Jun-Ichi, Kawabe, Koh-Ichi, Yuhki, Naofumi, Takehara, Naoyuki, Hasebe, Fumitaka, Ushikubi
Publikováno v:
Heart and vessels.
Ischemic preconditioning (IPC) describes a phenomenon wherein brief ischemia of the heart induces a potent cardioprotective mechanism against succeeding ischemic insult. Cyclooxygenase-2 (COX-2), a rate-limiting enzyme in prostanoid biosynthesis, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6623fc76978138eecc4b5133c440ff58
https://pubmed.ncbi.nlm.nih.gov/36522555
https://pubmed.ncbi.nlm.nih.gov/36522555
Autor:
Hitoshi Kashiwagi, Koh-ichi Yuhki, Yoshitaka Imamichi, Fumiaki Kojima, Shima Kumei, Tsunehito Higashi, Takahiro Horinouchi, Soichi Miwa, Shuh Narumiya, Fumitaka Ushikubi
Publikováno v:
TH Open, Vol 01, Iss 02, Pp e122-e129 (2017)
The results of studies that were performed to determine whether cigarette smoking affects platelet function have been controversial, and the effects of nicotine- and tar-free cigarette smoke extract (CSE) on platelet function remain to be determined.
Externí odkaz:
https://doaj.org/article/fba1e4b6dccf43528bc4de002045df76
Autor:
Satoru Takahashi, Koh-ichi Yuhki, Toshio Sekiguchi, Daisuke Mikami, Rafiqul Islam Khan, Yoshitaka Imamichi, Nobuo Suzuki, Masayuki Shimada, Fumitaka Ushikubi, Takashi Yazawa, Takeshi Kitano, Akihiro Umezawa, Takanobu Taniguchi, Kaoru Miyamoto, Junsuke Uwada
Publikováno v:
Molecular Reproduction and Development. 86:786-797
Cyclooxygenase 2 (COX-2) is an inducible rate-limiting enzyme for prostanoid production. Because COX-2 represents one of the inducible genes in mouse mesenchymal stem cells upon differentiation into Leydig cells, we investigated COX-2 expression and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c2a1f3105e165529868d0c090e2f72
https://doi.org/10.1002/mrd.23163
https://doi.org/10.1002/mrd.23163
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc6c894c5af5d90a220dfe1733289d96
https://doi.org/10.1254/jpssuppl.95.0_2-o-039
https://doi.org/10.1254/jpssuppl.95.0_2-o-039
Autor:
Shotaro Maehana, Fumitaka Ushikubi, Takafumi Ichikawa, Yoshitaka Imamichi, Koh-ichi Yuhki, Fumiaki Kojima, Hidero Kitasato, Masaki Nakamura, Hiroki Sekiya, Hitoshi Kashiwagi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO2-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::159500fe540b9f60b01858b355c474e7
https://doi.org/10.1254/jpssuppl.wcp2018.0_po2-6-32
https://doi.org/10.1254/jpssuppl.wcp2018.0_po2-6-32
Autor:
Toshikatsu Okumura, Fumiaki Kojima, Yoshitaka Imamichi, Koh-ichi Yuhki, Shuh Narumiya, Hitoshi Kashiwagi, Fumitaka Ushikubi, Shima Kumei
Publikováno v:
The FASEB Journal. 32:2354-2365
Nonalcoholic steatohepatitis (NASH) is a hepatic manifestation of metabolic syndrome. Although the prostaglandin (PG)I2 receptor IP is expressed broadly in the liver, the role of PGI2-IP signaling in the development of NASH remains to be determined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e0c89f5be2765092c39ea1b2240779
https://doi.org/10.1096/fj.201700590r
https://doi.org/10.1096/fj.201700590r
Autor:
Shima Kumei, Takahiro Horinouchi, Tsunehito Higashi, Fumiaki Kojima, Koh-ichi Yuhki, Soichi Miwa, Hitoshi Kashiwagi, Yoshitaka Imamichi, Fumitaka Ushikubi, Shuh Narumiya
Publikováno v:
TH Open, Vol 01, Iss 02, Pp e122-e129 (2017)
TH Open: Companion Journal to Thrombosis and Haemostasis
TH Open: Companion Journal to Thrombosis and Haemostasis
This is an open access article under the CC BY license.
The results of studies that were performed to determine whether cigarette smoking affects platelet function have been controversial, and the effects of nicotine- and tar-free cigarette smok
The results of studies that were performed to determine whether cigarette smoking affects platelet function have been controversial, and the effects of nicotine- and tar-free cigarette smok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92669e83342ec642e02f5571fba0fef
https://doi.org/10.1055/s-0037-1607979
https://doi.org/10.1055/s-0037-1607979