Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fumitaka Katoh"'
Autor:
Kohei Kagayama, Xin Zhang, Kiyoto Kageyama, Asami Hashino, Seigo Nagata, Fumitaka Katoh, Tomoko Niwa, Tatsuya Morimoto, Naoki Inoue, Jiro Shikaura
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:6959-6970
Inhibitors of phosphodiesterase 4 (PDE4) are an important class of anti-inflammatory drug that act by inhibiting the production of proinflammatory cytokines, including tumor necrosis factor-alpha (TNF-alpha). We have synthesized and evaluated a serie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2120ec2f6acd18b4abdf43d6fdbc6f7
https://doi.org/10.1016/j.bmc.2009.08.014
https://doi.org/10.1016/j.bmc.2009.08.014
Publikováno v:
Cancer Detection and Prevention. 31:332-338
Background : In an attempt to develop effective and non-cytotoxic cancer chemopreventive derivatives of retinoids, a novel acyclic retinoid has previously been synthesized. This acyclic retinoid, NIK-333, had been reported to suppress recurrence of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c936b91be3cdf2a2de92d71f4163d6
https://doi.org/10.1016/j.cdp.2007.06.001
https://doi.org/10.1016/j.cdp.2007.06.001
Autor:
Fujita F, Takuji Sugimoto, Masako Koike, Masato Matsuda, Yasuo Sakamoto, Masahide Fujita, Fumitaka Katoh, Kinuyo Komori
Publikováno v:
Cancer Science. 95:541-546
In contrast to findings in vitro, the clinical response to anticancer chemotherapy is not simply associated with the p53 mutation status. To analyze the relationship between the actual response of solid tumors with p53 mutation and other biological c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6617d875e806c59be53d35951f8af7
https://doi.org/10.1111/j.1349-7006.2004.tb03246.x
https://doi.org/10.1111/j.1349-7006.2004.tb03246.x
Autor:
Sakan Maeda, Kunihiko Yoshikawa, Fumitaka Katoh, Yukihiko Kitamura, Morihito Okada, Hiroshi Nojima, Noriaki Tsubota, Tatsuki R. Kataoka, Hideo Asada, Akihiko Ito, Hiroshi Yamasaki
Publikováno v:
Journal of Clinical Investigation. 105:1189-1197
F10 and BL6 sublines of B16 mouse melanoma cells are metastatic after intravenous injection, but only BL6 cells are metastatic after subcutaneous injection. We found that connexin (Cx) 26 is upregulated in BL6 cells. To examine gap junction formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f5f7abb69f0189250c3f6e68c56263
https://doi.org/10.1172/jci8257
https://doi.org/10.1172/jci8257
Autor:
Masaki Iwai, Saiyu Tanaka, Yoshinori Harada, Toshifumi Ohkusa, Takahiro Mori, Takeshi Okanoue, Fumitaka Katoh, Akira Muramatsu, Kei Kashima
Publikováno v:
Journal of Hepatology. 32:11-18
Background/Aims : We investigated the expression of connexin (Cx) 32 and 26 subunit proteins of the gap junction (GJ) in the rat liver during ontogenesis to clarify their roles in control of growth and differentiation, and observed their channels in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0175f464d2ece303e7a89dfc10e7311
https://doi.org/10.1016/s0168-8278(00)80184-1
https://doi.org/10.1016/s0168-8278(00)80184-1
Autor:
Fumitaka Katoh, Hiroshi Yamasaki
Publikováno v:
Carcinogenesis. 12:1923-1926
BALB/c 3T3 A31-1-13 cells are highly susceptible to chemical-induced cell transformation and their gap-junctional intercellular communication (GJIC) is decreased when these cells become confluent. On the other hand, A31-1-1 cells do not show such a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360744b95d84d3a59266e0f341bfd368
https://doi.org/10.1093/carcin/12.10.1923
https://doi.org/10.1093/carcin/12.10.1923
Autor:
Hironori Niizeki, Hideo Asada, Masahiro Tsutsumi, Fumitaka Katoh, Mamiko Saito-Katsuragi, Mikio Masuzawa, Hiroki Kuniyasu, Hiroshi Nojima, Akihiko Ito, Sachiko Miyagawa
Publikováno v:
Cancer. 110(5)
BACKGROUND. Connexins form the intercellular channels of the gap junction and play an integral part in a variety of biological functions, such as maintaining tissue homeostasis, cell growth control, and development. Previously it was demonstrated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66536a55e6b62de0cf3cd54b512e840
https://pubmed.ncbi.nlm.nih.gov/17614106
https://pubmed.ncbi.nlm.nih.gov/17614106
Autor:
Takuya Honmura, Ikumi Nishimura, Reiko Yamaguchi, Manabu Takagi, Fumitaka Katoh, Hiroyoshi Hidaka, Masaki Nogawa, Masato Matsuda, Shuuji Watanabe
Publikováno v:
Investigational new drugs. 21(4)
The cytotoxic effects of HMN-176 ((E)-4-[[2-N-[4-methoxybenzenesulfonyl] amino] stilbazole] 1-oxide; a newly synthesized compound, were evaluated and compared with those of the clinically used antitumor agents cis-platinum, adriamycin, etoposide, tax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079a317ebde7232a569e54aefcf438c4
https://pubmed.ncbi.nlm.nih.gov/14586206
https://pubmed.ncbi.nlm.nih.gov/14586206
Autor:
Hideki, Tanaka, Nobuko, Ohshima, Mami, Ikenoya, Kinuyo, Komori, Fumitaka, Katoh, Hiroyoshi, Hidaka
Publikováno v:
Cancer research. 63(20)
HMN-176 ((E)-4-[[2-N-[4-methoxybenzenesulfonyl]amino]stilbazole]1-oxide) is an active metabolite of HMN-214 ((E)-4-[2-[2-(N-acetyl-N-[4-methoxybenzenesulfonyl]amino)stilbazole]]1-oxide), which has a potent antitumor activity in mouse xenograft models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::221e40e0a2167cde563d74ad9084ad16
https://pubmed.ncbi.nlm.nih.gov/14583495
https://pubmed.ncbi.nlm.nih.gov/14583495
Autor:
J Imanishi, Tadashi Kodama, Toshihito Tanahashi, Masakazu Kita, Fumitaka Katoh, Yoshio Yamaoka, Naoki Sawai, Shoji Mitsufuji
Publikováno v:
Scopus-Elsevier
A method utilizing PCR-restriction fragment length polymorphism (RFLP) in the Helicobacter pylori genes is widely used to differentiate strains. However, with this typing method only a single base change at a specific restriction site can be detected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2849e2d40fe897a33cf3402e0822bb
https://pubmed.ncbi.nlm.nih.gov/10618081
https://pubmed.ncbi.nlm.nih.gov/10618081