Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Fumitaka Hashiya"'
Autor:
Sana Ohashi, Mayu Nakamura, Susit Acharyya, Masahito Inagaki, Naoko Abe, Yasuaki Kimura, Fumitaka Hashiya, Hiroshi Abe
Publikováno v:
ACS Omega, Vol 9, Iss 8, Pp 9300-9308 (2024)
Externí odkaz:
https://doaj.org/article/174520a4b4ef4cf1886fa54780aacf97
Autor:
Masahito Inagaki, Naoko Abe, Zhenmin Li, Yuko Nakashima, Susit Acharyya, Kazuya Ogawa, Daisuke Kawaguchi, Haruka Hiraoka, Ayaka Banno, Zheyu Meng, Mizuki Tada, Tatsuma Ishida, Pingxue Lyu, Kengo Kokubo, Hirotaka Murase, Fumitaka Hashiya, Yasuaki Kimura, Satoshi Uchida, Hiroshi Abe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Starting with the clinical application of two vaccines in 2020, mRNA therapeutics are currently being investigated for a variety of applications. Removing immunogenic uncapped mRNA from transcribed mRNA is critical in mRNA research and clini
Externí odkaz:
https://doaj.org/article/becbed75ef10423eb192e81f5310e9bc
Autor:
Sayaka Okahashi, Kenta Sakamoto, Fumitaka Hashiya, Keisuke Kumasaka, Taro Yamaguchi, Akitoshi Seiyama, Jun Utsumi
Publikováno v:
Advanced Biomedical Engineering. 12:81-90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ea1b2ec3ab9b8eb895bb6c349c66424
https://doi.org/10.14326/abe.12.81
https://doi.org/10.14326/abe.12.81
Autor:
Fumitaka Hashiya, Hirotaka Murase, Akash Chandela, Haruka Hiraoka, Masahito Inagaki, Yuko Nakashima, Naoko Abe, Mayu Nakamura, Goro Terai, Yasuaki Kimura, Kaori Ando, Natsuhisa Oka, Kiyoshi Asai, Hiroshi Abe
Publikováno v:
ChemBioChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce606b212a77d1ddb380cd566e14129
https://doi.org/10.1002/cbic.202200572
https://doi.org/10.1002/cbic.202200572
Autor:
Yuki Yoshida, Ti Zheng, Wataru Tanabe, Fumiaki Tomoike, Fumitaka Hashiya, Tetsuro Suzuki, Shuto Hirota, Yuriko Saiki, Akira Horii, Akiyoshi Hirayama, Tomoyosi Soga, Yasuaki Kimura, Hiroshi Abe
Publikováno v:
ChemMedChem. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff003e3773b87d78e3d44bdff75a6192
https://doi.org/10.1002/cmdc.202200450
https://doi.org/10.1002/cmdc.202200450
Publikováno v:
ChemBioChem. 22:2398-2406
Significant efforts have been made to develop therapeutic RNA aptamers that exploit synthetic RNA to capture target molecules. However, ensuring RNA aptamers are resistant against intrinsic nucleases remains an issue and restricts their use as therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2029e07e045df0e11200a92b567b642c
https://doi.org/10.1002/cbic.202100004
https://doi.org/10.1002/cbic.202100004
Autor:
Naoko Abe, Akihiro Imaeda, Masahito Inagaki, Zhenmin Li, Daisuke Kawaguchi, Kaoru Onda, Yuko Nakashima, Satoshi Uchida, Fumitaka Hashiya, Yasuaki Kimura, Hiroshi Abe
Publikováno v:
ACS chemical biology. 17(6)
Site-specific chemical modification of mRNA can improve its translational efficiency and stability. For this purpose, it is desirable to develop a complete chemical synthesis method for chemically modified mRNA. The key is a chemical reaction that in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9036836bbbaff70d2eb3910fe6aedd
https://pubmed.ncbi.nlm.nih.gov/35608277
https://pubmed.ncbi.nlm.nih.gov/35608277
Autor:
Yuki Yoshida, Ti Zheng, Wataru Tanabe, Fumiaki Tomoike, Fumitaka Hashiya, Tetsuro Suzuki, Shuto Hirota, Yuriko Saiki, Akira Horii, Akiyoshi Hirayama, Tomoyosi Soga, Yasuaki Kimura, Hiroshi Abe
Publikováno v:
ChemMedChem. 17(17)
Synthetic phosphate-derived functional groups are important for controlling the function of bioactive molecules in vivo. Herein we describe the development of a new type of biocompatible phosphate analog, a fluorophosphoramidate (FPA) functional grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f712b141882d30b9e3331b7491f5eafe
https://pubmed.ncbi.nlm.nih.gov/35393747
https://pubmed.ncbi.nlm.nih.gov/35393747
Publikováno v:
Chemistry – A European Journal. 26:15282-15289
The nucleosome is one of the most fundamental units involved in gene expression and consequent cell development, differentiation, and expression of cell functions. We report here a method to place reconstituted nucleosomes into a DNA origami frame fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f931c1be2a7a4827da5d97e29eeccd6d
https://doi.org/10.1002/chem.202003071
https://doi.org/10.1002/chem.202003071
Autor:
Naoko Abe, Yoshihiro Shimizu, Fumitaka Hashiya, Zhaoma Shu, Keiko Masuda, Lyu Fangjie, Bao T. Le, Rakesh N. Veedu, Yasuaki Kimura, Kosuke Nakamoto, Hiroshi Abe, Haruka Hiraoka
Publikováno v:
Chembiochem : a European journal of chemical biology. 22(24)
We have found that antisense oligonucleotides and siRNA molecules modified with repeat structures of disulfide units can be directly introduced into the cytoplasm and exhibit a suppressive effect on gene expression. In this study, we analyzed the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435737e70fadf8f5fb6651ccd158ce24
https://pubmed.ncbi.nlm.nih.gov/34636471
https://pubmed.ncbi.nlm.nih.gov/34636471