Výsledky vyhledávání - "Fumitaka HAYASE"

Identification of a novel advanced glycation end product derived from lactaldehyde

Autor: Hirohito Watanabe, Yoto Murakami, Fumitaka Hayase, Shiori Fujimoto, Haruna Miyake

Publikováno v: Bioscience, biotechnology, and biochemistry. 83(6)

Advanced glycation end products (AGEs) are implicated in the development of diabetic complications via the receptor for AGEs (RAGE). We have reported that the 3-hydroxypyridinium (3HP)-containing AGEs derived from α-hydroxyaldehydes physically inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cab15ce378b0dfd5acf249d0bb88b58
https://pubmed.ncbi.nlm.nih.gov/30822216

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Analysis of the cooked aroma and odorants that contribute to umami aftertaste of soy miso (Japanese soybean paste)

Autor: Sachie Kato, Miyu Saikusa, Fumitaka Hayase, Chihiro Suzuki, Yuriko Otsubo, Yutaro Tanaka, Yutaka Inoue, Hirohito Watanabe

Publikováno v: Food Chemistry. 213:521-528

Soy miso, the traditional Japanese fermented soybean paste prepared using soybean koji, is used for imparting umami aftertaste to cooked dishes. The objective of this study was to identify the key odorants of cooked soy miso and their influence on um

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cec1ea9e69609a597d9d41c1d31d960
https://doi.org/10.1016/j.foodchem.2016.06.106

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Identification of pyridinoline, a collagen crosslink, as a novel intrinsic ligand for the receptor for advanced glycation end-products (RAGE)

Autor: Toshiki Hasegawa, Hirohito Watanabe, Teruyuki Usui, Fumitaka Hayase, Takayuki Fujino, Ryotaro Kurachi, Yoto Murakami

Publikováno v: Bioscience, biotechnology, and biochemistry. 82(9)

Advanced glycation end-products (AGEs) elicit inflammatory responses via the receptor for AGEs (RAGE) and participate in the pathogenesis of diabetic complications. An earlier study showed that 3-hydroxypyridinium (3-HP), a common moiety of toxic AGE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2596f1c047812e2dd5a39af47f1c440d
https://pubmed.ncbi.nlm.nih.gov/29804507

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Receptor for advanced glycation end products (RAGE)-mediated cytotoxicity of 3-hydroxypyridinium derivatives

Autor: Teruyuki Usui, Hirohito Watanabe, Takayuki Fujino, Toshiki Hasegawa, Ryotaro Kurachi, Aya Miura, Fumitaka Hayase, Yoto Murakami, Takumi Daikoh

Publikováno v: Bioscience, biotechnology, and biochemistry. 82(2)

Advanced glycation end products (AGEs) formed from glyceraldehyde (Gcer) and glycolaldehyde (Gcol) are involved in the pathogenesis of diabetic complications, via interactions with a receptor for AGEs (RAGE). In this study, we aimed to elucidate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0af6cfb71a3b6b7a3a257221599082a
https://pubmed.ncbi.nlm.nih.gov/29316860

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Formation of N-(1-Oxo-2,4,5,6-hydroxyhexyl)-2'-deoxyguanosine by the Reaction of 2'-Deoxyguanosine with 3-Deoxyglucosone

Autor: Koji Kaneko, Fumitaka Hayase

Publikováno v: Bioscience, biotechnology, and biochemistry. 62(8)

3-Deoxyglucosone (3DG) has weaker mutagenicity than methylglyoxal by the Ames test. 3DG reacted readily with 2'-deoxyguanosine (dG) in nucleosides. Two major products (G-A and G-B) were isolated and purified from the reaction mixture of 50 mM 3DG and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b564b81c04c99679350ff4e8bc4dfbc6
https://pubmed.ncbi.nlm.nih.gov/27388850

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