Výsledky vyhledávání - "Fumitaka, Ushikubi"

Akademický článek

Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostaglandin E synthase-1

Autor: Fumiaki Kojima, Hiroki Sekiya, Yuka Hioki, Hitoshi Kashiwagi, Makoto Kubo, Masaki Nakamura, Shotaro Maehana, Yoshitaka Imamichi, Koh-ichi Yuhki, Fumitaka Ushikubi, Hidero Kitasato, Takafumi Ichikawa

Publikováno v: Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-24 (2022)

Abstract Background Microsomal prostaglandin E synthase-1 (mPGES-1) is a key enzyme that acts downstream of cyclooxygenase and plays a major role in inflammation by converting prostaglandin (PG) H2 to PGE2. The present study investigated the effect o

Externí odkaz: https://doaj.org/article/78235e4fb4724385b2106c700040599e

Zobrazit plný text záznamu

Prostaglandin E2 mediates the late phase of ischemic preconditioning in the heart via its receptor subtype EP4

Autor: Takayasu Kanno, Naoki Nakagawa, Tatsuya Aonuma, Jun-ichi Kawabe, Koh-ichi Yuhki, Naofumi Takehara, Naoyuki Hasebe, Fumitaka Ushikubi

Publikováno v: Heart and Vessels. 38:606-613

Ischemic preconditioning (IPC) describes a phenomenon wherein brief ischemia of the heart induces a potent cardioprotective mechanism against succeeding ischemic insult. Cyclooxygenase-2 (COX-2), a rate-limiting enzyme in prostanoid biosynthesis, is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f54d5938ba76b84e6fb1979a715b5d5
https://doi.org/10.1007/s00380-022-02219-4

Zobrazit plný text záznamu

Akademický článek

Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary

Autor: Yoshitaka Imamichi, Toshio Sekiguchi, Takeshi Kitano, Takashi Kajitani, Reiko Okada, Yoshihiko Inaoka, Kaoru Miyamoto, Junsuke Uwada, Satoru Takahashi, Takahiro Nemoto, Asuka Mano, Md Rafiqul Islam Khan, Md Tariqul Islam, Koh-ichi Yuhki, Hitoshi Kashiwagi, Fumitaka Ushikubi, Nobuo Suzuki, Takanobu Taniguchi, Takashi Yazawa

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Abstract Diethylstilbestrol (DES), a strong estrogenic compound, is well-known to affect the reproductive system. In this study, we investigated the effects of DES administration on gonadotropin levels and ovarian steroidogenesis in prepubertal rats.

Externí odkaz: https://doaj.org/article/4a1dd609111b43a18d7f939cc20bbcdb

Zobrazit plný text záznamu

Plný text ve formátu HTML

Prostaglandin E

Autor: Takayasu, Kanno, Naoki, Nakagawa, Tatsuya, Aonuma, Jun-Ichi, Kawabe, Koh-Ichi, Yuhki, Naofumi, Takehara, Naoyuki, Hasebe, Fumitaka, Ushikubi

Publikováno v: Heart and vessels.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6623fc76978138eecc4b5133c440ff58
https://pubmed.ncbi.nlm.nih.gov/36522555

Zobrazit plný text záznamu

Akademický článek

Cigarette Smoke Extract Inhibits Platelet Aggregation by Suppressing Cyclooxygenase Activity

Autor: Hitoshi Kashiwagi, Koh-ichi Yuhki, Yoshitaka Imamichi, Fumiaki Kojima, Shima Kumei, Tsunehito Higashi, Takahiro Horinouchi, Soichi Miwa, Shuh Narumiya, Fumitaka Ushikubi

Publikováno v: TH Open, Vol 01, Iss 02, Pp e122-e129 (2017)

The results of studies that were performed to determine whether cigarette smoking affects platelet function have been controversial, and the effects of nicotine- and tar-free cigarette smoke extract (CSE) on platelet function remain to be determined.

Externí odkaz: https://doaj.org/article/fba1e4b6dccf43528bc4de002045df76

Zobrazit plný text záznamu

Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate-induced colitis in mice lacking microsomal prostaglandin E synthase-1

Publikováno v: Inflammation and Regeneration
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-24 (2022)

BackgroundMicrosomal prostaglandin E synthase-1 (mPGES-1) is a key enzyme that acts downstream of cyclooxygenase and plays a major role in inflammation by converting prostaglandin (PG) H2to PGE2. The present study investigated the effect of genetic d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3248703454d409a5b0779cd695729b8
https://pubmed.ncbi.nlm.nih.gov/34983695

Zobrazit plný text záznamu

Cyclooxygenase‐2 is acutely induced by CCAAT/enhancer‐binding protein β to produce prostaglandin E 2 and F 2α following gonadotropin stimulation in Leydig cells

Autor: Satoru Takahashi, Koh-ichi Yuhki, Toshio Sekiguchi, Daisuke Mikami, Rafiqul Islam Khan, Yoshitaka Imamichi, Nobuo Suzuki, Masayuki Shimada, Fumitaka Ushikubi, Takashi Yazawa, Takeshi Kitano, Akihiro Umezawa, Takanobu Taniguchi, Kaoru Miyamoto, Junsuke Uwada

Publikováno v: Molecular Reproduction and Development. 86:786-797

Cyclooxygenase 2 (COX-2) is an inducible rate-limiting enzyme for prostanoid production. Because COX-2 represents one of the inducible genes in mouse mesenchymal stem cells upon differentiation into Leydig cells, we investigated COX-2 expression and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17c2a1f3105e165529868d0c090e2f72
https://doi.org/10.1002/mrd.23163

Zobrazit plný text záznamu

Prostaglandin I 2 suppresses the development of diet‐induced nonalcoholic steatohepatitis in mice

Autor: Toshikatsu Okumura, Fumiaki Kojima, Yoshitaka Imamichi, Koh-ichi Yuhki, Shuh Narumiya, Hitoshi Kashiwagi, Fumitaka Ushikubi, Shima Kumei

Publikováno v: The FASEB Journal. 32:2354-2365

Nonalcoholic steatohepatitis (NASH) is a hepatic manifestation of metabolic syndrome. Although the prostaglandin (PG)I2 receptor IP is expressed broadly in the liver, the role of PGI2-IP signaling in the development of NASH remains to be determined.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e0c89f5be2765092c39ea1b2240779
https://doi.org/10.1096/fj.201700590r

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání