Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fumio Nishikaku"'
Autor:
Fumio Nishikaku, Toshihiro Noguchi, Akemi Baba, Yasuyuki Tsutsumishita, Mitsuharu Hanada, Nobuyoshi Chiba, Takashi Yamaoka
Publikováno v:
Cancer Chemotherapy and Pharmacology
Background Miriplatin (formerly SM-11355), a novel lipophilic platinum complex developed to treat hepatocellular carcinoma, is administered into the hepatic artery using an oily lymphographic agent (Lipiodol Ultra-Fluide®) as a carrier. We clarified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c995d9a0b4aad19dfa5c32756b7b1f1
https://doi.org/10.1007/s00280-008-0895-3
https://doi.org/10.1007/s00280-008-0895-3
Autor:
Fumio Nishikaku, Yoshihiko Koga
Publikováno v:
Immunopharmacology. 25:65-74
The antiarthritic activity of a novel thiazole derivative, SM-8849, was compared with that of indomethacin and D-penicillamine, in mice with collagen-induced arthritis. SM-8849 reduced the incidence and severity of disease in collagen-immunized mice,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ea4ce5b1125de815f6fd5e18f06e3a
https://doi.org/10.1016/0162-3109(93)90031-k
https://doi.org/10.1016/0162-3109(93)90031-k
Autor:
Katsumi Eguchi, Tomoki Origuchi, Hiroaki Ida, Fumiko Tanaka, Kazuhiko Arima, Makoto Kamachi, Koichiro Aratake, A. Nozomi Iwanaga, Taiichiro Miyashita, Huang Mingguo, Yasumori Izumi, Atsushi Kawakami, Kiyoshi Migita, Koto Nakashima, Shuzo Tagashira, Seigou Abiru, Fumio Nishikaku, Mami Tamai
Publikováno v:
Biochemical and biophysical research communications. 312(2)
Akt is known to be activated in the rheumatoid synovial tissues. We examined here functional role of Akt during tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-mediated apoptosis in rheumatoid synovial cells. Rheumatoid synovial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847c0e43b088230156324d5f2c3d7716
https://pubmed.ncbi.nlm.nih.gov/14637151
https://pubmed.ncbi.nlm.nih.gov/14637151
Publikováno v:
International journal of immunopharmacology. 16(2)
To evaluate the antiarthritic properties of a novel thiazole derivative, the drugs SM-8849, D-penicillamine and indomethacin were administered to pristane-injected DBA/1 mice. The mice were treated daily with the agents for 32 weeks, starting from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad2ba6e73d250301ed52dfb6cf9dd94
https://pubmed.ncbi.nlm.nih.gov/7514159
https://pubmed.ncbi.nlm.nih.gov/7514159
Autor:
Fumio Nishikaku, Yoshihiko Koga
Publikováno v:
International journal of immunopharmacology. 13(5)
The effects of SM-8849 on the development of autoimmune disease in MRL/Mp-1pr/1pr mice were examined. SM-8849 improved survival as well as renal disease, restored the deficits in splenic cell responsiveness to stimulation by mitogens or conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfbd6c192fde679cec77c82c17b67f3
https://pubmed.ncbi.nlm.nih.gov/1783457
https://pubmed.ncbi.nlm.nih.gov/1783457