Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Fumio, Nakahara"'
Autor:
Qiaozhi Wei, Sandra Pinho, Shuxian Dong, Halley Pierce, Huihui Li, Fumio Nakahara, Jianing Xu, Chunliang Xu, Philip E. Boulais, Dachuan Zhang, Maria Maryanovich, Ana Maria Cuervo, Paul S. Frenette
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Haematopoietic stem cells (HSCs) are metabolically quiescent, with balanced myeloid and lymphoid potential. Here the authors show that MAEA is required in HSCs for ubiquitination and downregulation of surface cytokine receptors via autophagy; MAEA lo
Externí odkaz:
https://doaj.org/article/059f791163b643c18f32b07f9e23c4f7
Autor:
Chunliang Xu, Xin Gao, Qiaozhi Wei, Fumio Nakahara, Samuel E. Zimmerman, Jessica Mar, Paul S. Frenette
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Endothelial cells (EC) are known to contribute to haematopoietic stem cell (HSC) maintenance in the bone marrow (BM). Here the authors demonstrate that arterial ECs can be distinguished from sinusoidal ECs by podoplanin and Sca-1 expression, and that
Externí odkaz:
https://doaj.org/article/24eca0c01e8948c9b67d63080d2714e3
Autor:
Sandra Pinho, Qiaozhi Wei, Maria Maryanovich, Dachuan Zhang, Juan Carlos Balandrán, Halley Pierce, Fumio Nakahara, Anna Di Staulo, Boris A. Bartholdy, Jianing Xu, Daniel K. Borger, Amit Verma, Paul S. Frenette
Publikováno v:
Nat Cell Biol
Haematopoietic stem cells (HSCs) home to the bone marrow (BM) via, in part, the interactions with Vascular Cell Adhesion Molecule-1 (VCAM1)(1–3). Once into the BM, HSCs are vetted by perivascular phagocytes to ensure their self-integrity. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7beeb0e45c552e19017d6380b7f6ac1
https://doi.org/10.1038/s41556-022-00849-4
https://doi.org/10.1038/s41556-022-00849-4
Publikováno v:
Stem Cell Reports
Summary Hematopoietic cells differentiate through several progenitors in a hierarchical manner, and recent single-cell analyses have revealed substantial heterogeneity within each progenitor. Although common myeloid progenitors (CMPs) are defined as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca0cd5dd1b71ad89cf4d3ce6bbdf6c4
https://doi.org/10.1016/j.stemcr.2021.10.012
https://doi.org/10.1016/j.stemcr.2021.10.012
Autor:
Hisako Ikeda, Masayuki Komaba, Kumiko Komaba, Ayaka Matsuya, Akihiro Kawakubo, Fumio Nakahara
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196658 (2018)
Many animal species engage in social object play with movable objects. Two bottlenose dolphins (Tursiops truncatus) and one Risso's dolphin (Grampus griseus) owned by the Kujukushima Aquarium, Japan, occasionally shared and played with an object. Her
Externí odkaz:
https://doaj.org/article/5568fddb45af4a368889197cec93d3a7
Autor:
Mia Fujisawa, Miharu Yabe, Takashi Ueda, Motoki Kaneko, Makiko Monma, Takayoshi Suzuki, Ryutaro Fujimoto, Toshimasa Yabe, Hidekazu Suzuki, Hajime Mizukami, Masaya Sano, Fumio Nakahara, Erika Teramura, Masashi Matsushima
Publikováno v:
Internal Medicine
The risk of carcinogenesis increases after 20 years old in patients with Fanconi anemia (FA). We herein report three rare cases of FA combined with esophageal cancer in women; all patients were diagnosed with FA in early childhood. Patients 1 and 2 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56eea592c6d151489881417ba6b69768
https://doi.org/10.2169/internalmedicine.6926-20
https://doi.org/10.2169/internalmedicine.6926-20
Autor:
Takatoshi Kubo, Fumio Nakahara, Michiaki Sato, Kazuhiro Toyama, Megumi Yasunaga, Mineo Kurokawa, Osamu Abe, Naoki Okura, Masami Ohzu, Kumi Nakazaki
Publikováno v:
Annals of Hematology. 101:1153-1155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5de6a2d31d15f3cb6b2cfb1801dd7b86
https://doi.org/10.1007/s00277-021-04713-7
https://doi.org/10.1007/s00277-021-04713-7
Autor:
Hajime Mizukami, Tatehiro Kagawa, Yoshitaka Arase, Fumio Nakahara, Kota Tsuruya, Kazuya Anzai, Shunji Hirose, Koichi Shiraishi, Masako Shomura, Jun Koizumi, Kosuke Tobita, Tetsuya Mine
Publikováno v:
Case Reports in Oncology, Vol 5, Iss 2, Pp 380-384 (2012)
A 60-year-old man received interferon/ribavirin combination therapy for chronic hepatitis C in 2002 and achieved sustained virological response. In 2008, a hepatocellular carcinoma (HCC) with a diameter of 60 mm appeared and surgical resection was pe
Externí odkaz:
https://doaj.org/article/ecdaf35a827d408ab5dc02d3f5028f0e
Autor:
Atsuko Hadano, Mia Fujisawa, Jun Koike, Takayoshi Suzuki, Siho Yoshiwara, Takahiro Mori, Hidekazu Suzuki, Hajime Mizukami, Fumio Nakahara, Erika Teramura, Satoru Sugiyama, Makiko Monma, Masashi Matsushima, Masaya Sano
Publikováno v:
Progress of Digestive Endoscopy. 97:73-75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e948954cd1d0066e97f7493a7739f3a7
https://doi.org/10.11641/pde.97.1_73
https://doi.org/10.11641/pde.97.1_73
Autor:
John M. Greally, Ali H. Zahalka, Qiaozhi Wei, Avi Ma'ayan, Paul S. Frenette, Zichen Wang, Masako Suzuki, Maria Maryanovich, Chunliang Xu, Cristian Cruz, Sandra Pinho, Philip E. Boulais, Daniel K. Borger, Fumio Nakahara
Publikováno v:
Nature Cell Biology. 21:560-567
Haematopoietic stem cells (HSCs) are maintained by bone marrow niches in vivo1,2, but the ability of niche cells to maintain HSCs ex vivo is markedly diminished. Expression of niche factors by Nestin-GFP+ mesenchymal-derived stromal cells (MSCs) is d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8582750c971609f7a493a7119858551f
https://doi.org/10.1038/s41556-019-0308-3
https://doi.org/10.1038/s41556-019-0308-3