Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fumiko Yamairi"'
Publikováno v:
Rheumatology and Therapy, Vol 7, Iss 4, Pp 811-824 (2020)
Abstract Introduction The combination of methotrexate (MTX) with biological disease-modifying antirheumatic drugs (bDMARDs) is a recommended treatment option for rheumatoid arthritis (RA) patients showing an inadequate response to MTX monotherapy. Ho
Externí odkaz:
https://doaj.org/article/7afd04bc34e24797ad511d416a66c89e
Autor:
Hiroaki Sawamoto, Takashi Sasaki, Tomo Takegawa-Araki, Masayuki Utsugi, Hiroyuki Furukawa, Yoko Hirakawa, Fumiko Yamairi, Takashi Kurita, Karin Murahashi, Katsuya Yamada, Tetsuya Ohta, Shinji Kumagai, Akihiro Takemiya, Satoshi Obika, Jun Kotera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b93764df708ab4fcd102409e91a61dc
https://doi.org/10.2139/ssrn.4363909
https://doi.org/10.2139/ssrn.4363909
Autor:
Saori Yamauchi, Mitsumasa Kishimoto, Noriko Sato, Jun Kobayashi, Tomohisa Iwasaki, Fumiko Yamairi
Publikováno v:
Rheumatology and Therapy
Introduction Although the proportion of patients with rheumatoid arthritis (RA) using biologic disease-modifying antirheumatic drugs (bDMARDs) has increased steadily, the relationship between patient background and preference for bDMARDs has not been
Publikováno v:
Rheumatology and Therapy
Rheumatology and Therapy, Vol 7, Iss 4, Pp 811-824 (2020)
Rheumatology and Therapy, Vol 7, Iss 4, Pp 811-824 (2020)
Introduction The combination of methotrexate (MTX) with biological disease-modifying antirheumatic drugs (bDMARDs) is a recommended treatment option for rheumatoid arthritis (RA) patients showing an inadequate response to MTX monotherapy. However, th
Autor:
Takashi Sasaki, Yoko Hirakawa, Fumiko Yamairi, Takashi Kurita, Karin Murahashi, Hirokazu Nishimura, Norihiko Iwazaki, Hidenori Yasuhara, Takashi Tateoka, Tetsuya Ohta, Satoshi Obika, Jun Kotera
Publikováno v:
Nucleic acid therapeutics. 32(3)
Guanidine-bridged nucleic acid (GuNA) is a novel 2',4'-bridged nucleic acid/locked nucleic acid (2',4'-BNA/LNA) analog containing cations that exhibit strong affinity for target RNA and superior nuclease resistance. In this study
Autor:
Yosuke Inui, Akiyoshi Fukamizu, Fumiko Yamairi, Hideki Mochida, Kenji Arakawa, Junji Ishida, Miyoko Okada
Publikováno v:
Biomedical Reports. 1:359-364
Renal dysfunction is accelerated by various factors such as hypertension, aging and diabetes. Glomerular hyper-filtration, considered one of the major risk factors leading to diabetic nephropathy, is often encountered in diabetic patients. However, t
Autor:
Teita Asano, Nanako Matsui, Masaya Takehara, Masaki Makise, Fumiko Yamairi, Tohru Mizushima, Naoko Takahashi
Publikováno v:
Journal of Biochemistry. 143:455-465
Origin recognition complex (ORC), a six-protein complex (Orc1p-Orc6p), may deeply involve in initiation of chromosomal DNA replication. However, since most temperature-sensitive orc mutants of Saccharomyces cerevisiae show the accumulation of cells w
Autor:
Yoshihiro Yamaguchi, Fumiko Yamairi, Hitomi Takenaka, Masaki Makise, Naoko Takahashi, Tomofusa Tsuchiya, Tohru Mizushima
Publikováno v:
Journal of Biological Chemistry. 279:8469-8477
Orc5p is one of six proteins that make up the origin recognition complex (ORC), a candidate initiator of chromosomal DNA replication in eukaryotes. To investigate the role of ATP binding to Orc5p in cells, we constructed orc5-A, a strain of Saccharom
Autor:
Fumiko Yamairi, Yuuichi Ono, Masaharu Tanaka, Hiroyuki Utsumi, Naruyasu Komorita, Atsushi Fukunari
Publikováno v:
Journal of Toxicologic Pathology
Vascular endothelial growth factor (VEGF) and its receptors have recently reported to be expressed in human osteoarthritis (OA), suggesting that VEGF could be implicated in the pathogenesis of this disease. In the present study, expression of VEGF in
Autor:
Tomofusa Tsuchiya, Kazuya Matsuda, Fumiko Yamairi, Naoko Takahashi, Masaki Makise, Keitarou Suzuki, Tohru Mizushima
Publikováno v:
The Biochemical journal. 402(2)
Orc5p is one of six subunits constituting the ORC (origin recognition complex), a possible initiator of chromosomal DNA replication in eukaryotes. Orc5p contains a Walker A motif. We recently reported that a strain of Saccharomyces cerevisiae having