Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fumiko Sunaga"'
Autor:
Takeharu Nagai, Mamiko Tsugane, Seigo Araki, Masahiro Nakano, Hiroaki Suzuki, Fumiko Sunaga, Mitsuru Hattori, Masayoshi Nakano
Publikováno v:
The Analyst. 145:667-674
We investigated the capability of simple microfluidic devices with trenches having vertical sidewalls for live-cell fluorescence imaging of adherent cells. An epithelial cell line that forms a two-dimensional (2D) sheet was cultured to adhere to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d04b1d07d507bc181bd07fabc7b3327
https://doi.org/10.1039/c9an02165e
https://doi.org/10.1039/c9an02165e
Autor:
Tsuda Soichiro, Yoda Takuya, Ayumi Matsuhashi, Ai Matsushita, Fumiko Sunaga, Yukie Sasakura, Kazuteru Aoki, Masahito Hosokawa
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2-S18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed141f412d5322a1d9ba8448be9ef1f6
https://doi.org/10.1254/jpssuppl.95.0_2-s18-3
https://doi.org/10.1254/jpssuppl.95.0_2-s18-3
Publikováno v:
2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS).
We developed a microdevice that measures material permeation via epithelial tight junction (TJ) to evaluate its barrier function. This device is equipped with microchambers filled with collagen gel, so that a flat epithelial sheet is formed. Since th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8156cb5cf4fcaa220b5560cd2ac38f3
https://doi.org/10.1109/mems46641.2020.9056331
https://doi.org/10.1109/mems46641.2020.9056331
Autor:
Miki Bundo, Tatsuro Asai, Kazuya Iwamoto, Jun Ishigooka, Tadafumi Kato, Fumiko Sunaga, Junko Ueda, Kiyoto Kasai, Hiroko Sugawara
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 56:117-121
Epigenetic regulation may be involved in the pathophysiology of mental disorders, such as schizophrenia and bipolar disorder, and in the pharmacological action of drugs. Characterizing the epigenetic effects of drugs is an important step to optimal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad3acbd60f2bb99a69f8ebb7b05883c
https://doi.org/10.1016/j.pnpbp.2014.08.010
https://doi.org/10.1016/j.pnpbp.2014.08.010
Publikováno v:
Neuroscience Letters. 563:123-128
Blonanserin is a second-generation antipsychotic drug for schizophrenia. The pharmacological actions of blonanserin are shown to be the antagonism of dopamine receptor 2 and serotonin receptors. However, its molecular mechanisms in brain cells have n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165d72e4b3391ac12143831e68086afa
https://doi.org/10.1016/j.neulet.2014.01.038
https://doi.org/10.1016/j.neulet.2014.01.038
Autor:
Kazuya Iwamoto, Kiyoto Kasai, Gen Tanaka, Hiroko Sugawara, Fumiko Sunaga, Miki Bundo, Tatsuro Asai, Tadafumi Kato, Junko Ueda, Jun Ishigooka
Publikováno v:
International Journal of Neuropsychopharmacology. 16:2285-2294
Unraveling the epigenetic status of neuronal cells in the brain is critical to our understanding of the pathophysiology of psychiatric disorders, which may reflect a complex interaction between genetic and environmental factors. Several epigenetic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f401358bf5db733a1b7272ec2d8fd777
https://doi.org/10.1017/s1461145713000710
https://doi.org/10.1017/s1461145713000710
Publikováno v:
The Proceedings of the Symposium on Micro-Nano Science and Technology. :19pm5PN326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b791648bb627047373e5918b3b19e33
https://doi.org/10.1299/jsmemnm.2019.10.19pm5pn326
https://doi.org/10.1299/jsmemnm.2019.10.19pm5pn326
Autor:
Fumichika Nishimura, Fumiko Sunaga, Kazuya Iwamoto, Akane Yoshikawa, Tempei Ikegame, Chihiro Kakiuchi, Tadafumi Kato, Tatsuro Asai, Miki Bundo, Tsukasa Sasaki, Mamoru Tochigi, Kiyoto Kasai, Yoshiya Kawamura, Hiroyuki Hibino
Publikováno v:
Neuroscience research. 77(4)
Accumulating evidence suggests that epigenetic alterations in brain-derived neurotrophic factor (BDNF) promoters are associated with the pathophysiology of psychiatric disorders. Epigenetic changes in BDNF were reported not only in brain tissues but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc6829d1a7e0759a64fc4c346d4b8e5
https://pubmed.ncbi.nlm.nih.gov/23973796
https://pubmed.ncbi.nlm.nih.gov/23973796
Publikováno v:
Clinical Epigenetics, Vol 4, Iss 1, p 22 (2012)
Clinical Epigenetics
Clinical Epigenetics
Background Studying DNA methylation profiles in detail should be the first step in epigenetic research. Although sodium bisulfite modification of genomic DNA is the gold standard method for DNA methylation analysis, this method results in the loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ba4d53d050d3897b293ebfb69366bc
http://www.clinicalepigeneticsjournal.com/content/4/1/22
http://www.clinicalepigeneticsjournal.com/content/4/1/22
Autor:
Takashi Shimada, Yukihiko Hirai, Takayuki Kubodera, Azat Mayra, Hidehiro Mizusawa, Hiroyuki Tomimitsu, Takanori Yokota, Wenying Piao, Fumiko Sunaga, Masaki Kobayashi
Publikováno v:
Biochemical and biophysical research communications. 405(2)
Systemic injections of AAV vectors generally transduce to the liver more effectively than to cardiac and skeletal muscles. The short hairpin RNA (shRNA)-expressing AAV9 (shRNA-AAV9) can also reduce target gene expression in the liver, but not enough
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814d7b2706bbe80f5786dbd8b146b2ac
https://pubmed.ncbi.nlm.nih.gov/21219850
https://pubmed.ncbi.nlm.nih.gov/21219850