Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Fumiko Shiroki"'
Autor:
Tomomitsu Doi, Mari Fujiwara, Yoshito Mochizuki, Harumi Suzuki, Shigeo Koyasu, Fumiko Shiroki, Satoshi Matsuda, Takashi Kadowaki
Publikováno v:
The Journal of Immunology. 178:1349-1356
We examined the role of class IA PI3K in pre-TCR controlled beta-selection and TCR-controlled positive/negative selection in thymic development. Using mice deficient for p85alpha, a major regulatory subunit of the class IA PI3K family, the role of cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a135a634e2bebd168e6eebd8631d35
https://doi.org/10.4049/jimmunol.178.3.1349
https://doi.org/10.4049/jimmunol.178.3.1349
Autor:
Yutaka Arimura, Shingo Kuwahara, Hidehito Kato, Junji Yagi, Umberto Dianzani, Fumiko Shiroki, Takehiko Uchiyama
Publikováno v:
Journal of Biological Chemistry. 279:11408-11416
Both CD28 and its relative, inducible costimulator (ICOS), have a binding motif for phosphatidylinositol 3-kinase (PI3K) in their cytoplasmic tail, and the binding of PI3K leads to activation of a serine/threonine kinase, Akt. The role of Akt in cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e8345f271f84eecb527121285de1bf
https://doi.org/10.1074/jbc.m309063200
https://doi.org/10.1074/jbc.m309063200
Autor:
Derin B. Keskin, Ellis L. Reinherz, Fumiko Shiroki, Linda K. Clayton, Maki Touma, Shigeo Koyasu, Ibuki Saito
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(8)
IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. Mice carrying a targeted gene disruption of IκBNS demonstrate dysregulation of cytokines in T cells, macrophages, and dendr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03b739df6579ce4d4175811901fe0d0
https://pubmed.ncbi.nlm.nih.gov/21900180
https://pubmed.ncbi.nlm.nih.gov/21900180