Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Fumiko Saito-Ohara"'
Autor:
Yoji Hakamata, Kenji Kuroiwa, Masaru Ichida, Yasumitsu Nagao, Satoshi Yamamoto, Hitoshi Endo, Fumiko Saito-Ohara, Kaoru Tominaga
Publikováno v:
Transgenic Research. 23:757-765
We developed a transgenic mouse line with Y chromosome-linked green fluorescent protein expressing transgenes (Y-GFP) by the conventional microinjection into the pronucleus of C57BL/6J fertilized oocytes. Embryonic stem (ES) cells derived from Y-GFP
Autor:
Shunsuke Ishii, Toshio Maekawa, Toshie Shinagawa, Yuji Sano, Jun Yokota, Takashi Kohno, Koichi Nagasaki, Johji Inazawa, Fumiko Saito-Ohara, Takahiko Sakuma, Shintaro Nomura, Yoshio Miki
Publikováno v:
Molecular and Cellular Biology. 27:1730-1744
Transcription factor ATF-2 is a nuclear target of stress-activated protein kinases, such as p38, which are activated by various extracellular stresses, including UV light. Here, we show that ATF-2 plays a critical role in hypoxia- and high-cell-densi
Publikováno v:
The Journal of Immunology. 172:4858-4865
Pax-5 is the key regulator in B cell development. Pax-5-deficient mice show defects in B cell commitment and recombination of IgH chain gene rearrangement from DJ to VDJ. Previously, we found that Pax-5 bound to KI and KII sites, which play a crucial
Autor:
Kohichiroh Yasui, Hiroyuki Okamoto, Tadao Funato, Seiji Naito, Takashi Tsuruo, Johji Inazawa, Chen Zhao, Akira Yokomizo, Akihiro Tomida, Fumiko Saito-Ohara, Issei Imoto, Saori Mihara
Publikováno v:
Cancer Research. 64:1403-1410
Chemoresistance is a major obstacle for successful treatment of cancer. To identify regions of the genome associated with acquired resistance to therapeutic drugs, we conducted molecular cytogenetic analyses of 23 cancer-cell lines, each resistant to
Autor:
Fumiko Saito-Ohara, Yoji Fukuda, Yusuke Nakamura, Johji Inazawa, Masafumi Matsuo, Kishan Lal Agarwala, Kazuhiro Yamakawa, Masahiro Ito, Issei Imoto, Masaharu Hayashi
Publikováno v:
The American Journal of Human Genetics. 71:637-645
A male patient with profound mental retardation, athetosis, nystagmus, and severe congenital hypotonia (Duchenne muscular dystrophy [DMD]) was previously shown to carry a pericentric inversion of the X chromosome, 46,Y,inv(X)(p21.2q22.2). His mother
Autor:
Setsuo Hirohashi, Kohichiroh Yasui, Takashi Takahashi, Toshihiko Iizasa, Takeo Terasaki, Sana Yokoi, Takehiko Fujisawa, Fumiko Saito-Ohara, Katsumi Koshikawa, Johji Inazawa, Akira Horii
Publikováno v:
The American Journal of Pathology. 161:207-216
We investigated DNA copy-number aberrations in 22 cell lines derived from small cell lung cancers (SCLCs) using comparative genomic hybridization. A minimal common region at 5p13, within the 5p11-p13 amplicon that was most frequently involved, harbor
Publikováno v:
Journal of Cranio-Maxillofacial Surgery. 28:165-170
Chromosome 4p- syndrome is a multiple malformation syndrome associated with partial deletion of the short arm of chromosome 4 (4p-). It is characterized by dysmorphic features and retarded development. Cleft lip and/or palate are the major clinical m
Autor:
Hiroo Murakami, Zeng-Quan Yang, Takehide Murata, Chie Koga, Kailai Sun, Tatsuro Ikeuchi, Naoki Adati, Christian Geltinger, Kazunari K. Yokoyama, Jun Song, Keiichi Itakura, Fumiko Saito-Ohara, Ichirou Kanazawa, Masatoshi Matsumura
Publikováno v:
Genomics. 52:374-377
KNSL4 (Kid; kinesin-like DNA-binding protein) is a member of the kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Myc-associated zinc finger protein (MAZ) participates in both the initi
Autor:
Tatsro Ikeuchi, Sei Sasaki, Fumiko Saito-Ohara, Yukio Kageyama, Kazushi Yamauchi, Kenichi Ishibashi, Fumiaki Marumo
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1399:62-66
The cDNA for the seventh mammalian aquaporin (AQP7) was isolated from rat testis, and its expression demonstrated at the tail of late spermatids (Ishibashi et al., J. Biol. Chem. 272 (1997) 20,782-20,786). Here we report the isolation of the mouse an
Autor:
Hirokazu Kurokawa, Nagahiro Saijo, Kazuto Nishio, Toshihiro Suzuki, Tatsuro Ikeuchi, Masaaki Terada, Shinzo Tanabe, Fumiko Saito-Ohara, Hiroki Sasaki
Publikováno v:
Biochemical and Biophysical Research Communications. 238:790-794
Members of the ATP binding cassette (ABC) superfamily are involved in the energy-dependent transport of a wide variety of substrates including anticancer agents across the membranes. We have cloned a cDNA fragment including a novel ABC sequence from