Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Fumiko Chiwaki"'
Autor:
Mizuki Kanda, Satoshi Serada, Kosuke Hiramatsu, Masashi Funauchi, Kengo Obata, Satoshi Nakagawa, Tomoharu Ohkawara, Okinori Murata, Minoru Fujimoto, Fumiko Chiwaki, Hiroki Sasaki, Yutaka Ueda, Tadashi Kimura, Tetsuji Naka
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 35, Iss , Pp 100853- (2023)
Background: Epithelial ovarian cancer (EOC) is a lethal malignant tumor, for which new treatment options are urgently required. Lipolysis-stimulated lipoprotein receptor (LSR) is widely expressed in EOC, and it is associated with poor prognosis. In t
Externí odkaz:
https://doaj.org/article/8aca4d3343e645dd80e48e4e7a9fbf33
Autor:
Yusuke Kobayashi, Takashi Takeda, Haruko Kunitomi, Fumiko Chiwaki, Masayuki Komatsu, Shimpei Nagai, Yuya Nogami, Kosuke Tsuji, Kenta Masuda, Hideaki Ogiwara, Hiroki Sasaki, Kouji Banno, Daisuke Aoki
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 124 (2022)
In the field of drug repurposing, the use of statins for treating dyslipidemia is considered promising in ovarian cancer treatment based on epidemiological studies and basic research findings. Biomarkers should be established to identify patients who
Externí odkaz:
https://doaj.org/article/5ddd2aedd42840f7a238eb036ee71cc6
Autor:
Yosuke Tanaka, Kazuhiko Aoyagi, Keiko Minashi, Rie Komatsuzaki, Masayuki Komatsu, Fumiko Chiwaki, Masashi Tamaoki, Takao Nishimura, Naoki Takahashi, Ichiro Oda, Yuji Tachimori, Tokuzo Arao, Kazuto Nishio, Shigehisa Kitano, Kenta Narumi, Kazunori Aoki, Satoshi Fujii, Atsushi Ochiai, Teruhiko Yoshida, Manabu Muto, Yasuhide Yamada, Hiroki Sasaki
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143804 (2015)
Definitive chemoradiotherapy (CRT) is a less invasive therapy for esophageal squamous cell carcinoma (ESCC). Five-year survival rate of locally advanced ESCC patients by definitive CRT were 37%. We previously reported that tumor-specific cytotoxic T-
Externí odkaz:
https://doaj.org/article/17f86009996841d4a7eeb10a20f4fbdf
Autor:
Masami Suzuki, Fumiko Chiwaki, Yumi Sawada, Maho Ashikawa, Kazuhiko Aoyagi, Takeshi Fujita, Kazuyoshi Yanagihara, Masayuki Komatsu, Minoru Narita, Tsutomu Suzuki, Hiroshi Nagase, Ryoji Kushima, Hiromi Sakamoto, Takeo Fukagawa, Hitoshi Katai, Hitoshi Nakagama, Teruhiko Yoshida, Yasuhito Uezono, Hiroki Sasaki
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123407 (2015)
The dormancy of tumor cells is a major problem in chemotherapy, since it limits the therapeutic efficacy of anti-tumor drugs that only target dividing cells. One potential way to overcome chemo-resistance is to "wake up" these dormant cells. Here we
Externí odkaz:
https://doaj.org/article/0ea575147661431498c338d3c2f83e28
Autor:
Takeshi Fujita, Fumiko Chiwaki, Ryou-u Takahashi, Kazuhiko Aoyagi, Kazuyoshi Yanagihara, Takao Nishimura, Masashi Tamaoki, Masayuki Komatsu, Rie Komatsuzaki, Keisuke Matsusaki, Hitoshi Ichikawa, Hiromi Sakamoto, Yasuhide Yamada, Takeo Fukagawa, Hitoshi Katai, Hiroyuki Konno, Takahiro Ochiya, Teruhiko Yoshida, Hiroki Sasaki
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130808 (2015)
Diffuse-type solid tumors are often composed of a high proportion of rarely proliferating (i.e., dormant) cancer cells, strongly indicating the involvement of cancer stem cells (CSCs) Although diffuse-type gastric cancer (GC) patients have a poor pro
Externí odkaz:
https://doaj.org/article/94b73f81ba67482fa2b952678f0c12ae
Autor:
Masayuki Komatsu, Hitoshi Ichikawa, Fumiko Chiwaki, Hiromi Sakamoto, Rie Komatsuzaki, Makoto Asaumi, Kazuhisa Tsunoyama, Takeo Fukagawa, Hiromichi Matsushita, Narikazu Boku, Keisuke Matsusaki, Fumitaka Takeshita, Teruhiko Yoshida, Hiroki Sasaki
Publikováno v:
Oncogene. 41:4779-4794
Genetic alteration of Rho GTPase-activating proteins (ARHGAP) and GTPase RhoA is a hallmark of diffuse-type gastric cancer and elucidating its biological significance is critical to comprehensively understanding this malignancy. Here, we report that
Autor:
Takahiro Ochiya, Hiroki Sasaki, Kazuhiko Aoyagi, Fumiko Chiwaki, Masamichi Ishiai, Tetsuji Nagao, Kazuo Fujikawa, Kouichi Tatsumi, Ryou-u Takahashi, Ayako Inoue, Hiroshi Tanooka
Table S1. Synthetic DNA oligomers, PCR primers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa8d13e7ec0b033b838ab9bc0637fc0
https://doi.org/10.1158/1541-7786.22517460.v1
https://doi.org/10.1158/1541-7786.22517460.v1
Autor:
Takahiro Ochiya, Hiroki Sasaki, Kazuhiko Aoyagi, Fumiko Chiwaki, Masamichi Ishiai, Tetsuji Nagao, Kazuo Fujikawa, Kouichi Tatsumi, Ryou-u Takahashi, Ayako Inoue, Hiroshi Tanooka
Supplementary Fig. S1. Nedd9 and Aurkb seed match sequences in mucAB and umuDC.Supplementary Fig. S2. Selection of cells expressing Tet-repressor protein.Supplementary Fig. S3. Microarray analysis of deregulated oncogenes.Supplementary Fig. S4. Suppr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3561d203acbe8e3d7596af26924169ed
https://doi.org/10.1158/1541-7786.22517463
https://doi.org/10.1158/1541-7786.22517463
Autor:
Satoshi Inoue, Narikazu Boku, Fumiko Chiwaki, Keisuke Matsusaki, Hiroyuki Mano, Hiroki Sasaki, Masahito Kawazu, Yae Kanai, Hiromichi Matsushita, Toshihide Ueno, Shigeki Sekine, Yasushi Yatabe, Shinya Kojima, Masayuki Komatsu, Yosuke Tanaka
Publikováno v:
Nature Cancer. 2:962-977
Peritoneal metastasis, a hallmark of incurable advanced gastric cancer (GC), presently has no curative therapy and its molecular features have not been examined extensively. Here we present a comprehensive multi-omic analysis of malignant ascitic flu
Autor:
Mizuki Kanda, Satoshi Serada, Kosuke Hiramatsu, Masashi Funauchi, Kengo Obata, Satoshi Nakagawa, Tomoharu Ohkawara, Okinori Murata, Minoru Fujimoto, Fumiko Chiwaki, Hiroki Sasaki, Yutaka Ueda, Tadashi Kimura, Tetsuji Naka
Publikováno v:
Neoplasia (New York, N.Y.). 35
Epithelial ovarian cancer (EOC) is a lethal malignant tumor, for which new treatment options are urgently required. Lipolysis-stimulated lipoprotein receptor (LSR) is widely expressed in EOC, and it is associated with poor prognosis. In this study, w