Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Fumihito Saitow"'
Autor:
Kota Tamada, Keita Fukumoto, Tsuyoshi Toya, Nobuhiro Nakai, Janak R. Awasthi, Shinji Tanaka, Shigeo Okabe, François Spitz, Fumihito Saitow, Hidenori Suzuki, Toru Takumi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Duplication of chromosome 15q11-q13 is associated with autism spectrum disorder (ASD). Here, the authors show that in mice paternal Dup15q results in ASD-like neuronal and behavioural impairment driven by Necdin.
Externí odkaz:
https://doaj.org/article/a34621df8ce54a06a59e939a043096f2
Autor:
Masatoshi Nagano, Fumihito Saitow, Shinpei Higo, Makoto Uzuki, Yasunori Mikahara, Toshio Akimoto, Hitoshi Ozawa, Katsuhiko Nishimori, Hidenori Suzuki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Cesarean section (C/S) is one way of delivering babies, and is chosen when mothers or babies are facing problems or life-threatening conditions during pregnancy. Many meta-analyses have suggested an etiological relationship between C/S deliv
Externí odkaz:
https://doaj.org/article/7c7854fce09a4fc88b38632b81184079
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Serotonin (5-HT) is a well-known modulator of behavioral, physiological, and emotional functions of the forebrain region. We recently discovered alterations of serotonergic synaptic modulations in both, the prefrontal cortex (PFC) and the so
Externí odkaz:
https://doaj.org/article/634f9f89495241d08d6916a859d2aad8
Autor:
Atsushi Sakai, Fumihito Saitow, Motoyo Maruyama, Noriko Miyake, Koichi Miyake, Takashi Shimada, Takashi Okada, Hidenori Suzuki
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Dysregulation of voltage gated potassium channels is a feature of neuropathic pain. Here in a rat model the authors identify the microRNA cluster miR-17-92 as a regulator of voltage gated potassium channels in the dorsal root ganglion neurons.
Externí odkaz:
https://doaj.org/article/5788276780e241bcaf419fe9f61a344e
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186584 (2017)
Previous studies have shown that phenotypic modulation of smooth muscle cells (SMCs) plays a pivotal role in human diseases. However, the molecular mechanisms underlying the reversible differentiation of SMCs remain elusive particularly because cultu
Externí odkaz:
https://doaj.org/article/88ca204fa2c444c5871a3096351c04ba
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150636 (2016)
Cerebellar GABAergic inhibitory transmission between interneurons and Purkinje cells (PCs) undergoes a long-lasting enhancement following different stimulations, such as brief depolarization or activation of purinergic receptors of postsynaptic PCs.
Externí odkaz:
https://doaj.org/article/cbd90e4c377e4e53ae7e394b274a590f
Autor:
Moritoshi Hirono, Fumihito Saitow, Moeko Kudo, Hidenori Suzuki, Yuchio Yanagawa, Masahisa Yamada, Soichi Nagao, Shiro Konishi, Kunihiko Obata
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29663 (2012)
Inhibitory interneurons in the cerebellar granular layer are more heterogeneous than traditionally depicted. In contrast to Golgi cells, which are ubiquitously distributed in the granular layer, small fusiform Lugaro cells and globular cells are loca
Externí odkaz:
https://doaj.org/article/691052ee111942189c933a8585632166
Autor:
Fumihito Saitow, Shinji Tanaka, Janak R. Awasthi, Kota Tamada, François Spitz, Keita Fukumoto, Nobuhiro Nakai, Hidenori Suzuki, Tsuyoshi Toya, Toru Takumi, Shigeo Okabe
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Maternally inherited duplication of chromosome 15q11-q13 (Dup15q) is a pathogenic copy number variation (CNV) associated with autism spectrum disorder (ASD). Recently, paternally derived duplication has also been shown to contribute to the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a660dc78957cee8045fe745cdde1c9fb
https://doaj.org/article/a34621df8ce54a06a59e939a043096f2
https://doaj.org/article/a34621df8ce54a06a59e939a043096f2
Publikováno v:
Neuroscience. 394:267-285
Deficits in dopaminergic function are thought to underlie attention-deficit/hyperactivity disorder (ADHD). Dopaminergic neurons are the main source of dopamine (DA), a neurotransmitter that acts as a neuromodulator of cognitive function in the prefro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6160cdb2120e18b53a69ad00fbe16414
https://doi.org/10.1016/j.neuroscience.2018.10.039
https://doi.org/10.1016/j.neuroscience.2018.10.039
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 96:4-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6e66f5ef1aeeb5689fc43ddd0f0a84
https://doi.org/10.1254/jpssuppl.96.0_4-b-p-303
https://doi.org/10.1254/jpssuppl.96.0_4-b-p-303