Výsledky vyhledávání - "Fumihito Kugimiya"

β-Blockers are associated with increased B-type natriuretic peptide levels differently in men and women in heart failure with preserved ejection fraction

Autor: Eisaku Harada, Yuji Mizuno, Masanobu Ishii, Toshifumi Ishida, Toshihiro Yamada, Fumihito Kugimiya, Hirofumi Yasue

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 323:H276-H284

β-Blocker (BB) use is a mainstay for the treatment of heart failure (HF) with reduced ejection fraction (HFrEF), whereas its efficacy for heart failure with preserved ejection fraction (HFpEF) remains controversial. Women outnumber men in HFpEF, whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1fa0032ac31de5c3a84e48dd5477a8
https://doi.org/10.1152/ajpheart.00029.2022

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East Asians Variant Mitochondrial Aldehyde Dehydrogenase 2 Genotype Exacerbates Nitrate Tolerance in Patients With Coronary Spastic Angina

Autor: Izumi Kusumegi, Fumihito Kugimiya, Yuji Mizuno, Michihiro Yoshimura, Hirofumi Yasue, Makoto Shono, Eisaku Harada, Kenji Kinoshita

Publikováno v: Circulation Journal. 84:479-486

BACKGROUND Aldehyde dehydrogenase 2 (ALDH2) plays a central role in the biotransformation of glyceryl trinitrate (GTN) or nitroglycerin, which is widely used for the treatment of coronary artery disease (CAD). The deficient variant ALDH2 genotype (AL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2cbca62e1d7df9d5de9f9402399182
https://doi.org/10.1253/circj.cj-19-0989

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Sex Differences in Heart Failure With Preserved Ejection Fraction Reflected by B-type Natriuretic Peptide Level

Autor: Hirofumi Yasue, Yuji Mizuno, Hiroyuki Maeda, Naotsugu Yano, Eisaku Harada, Fumihito Kugimiya, Makoto Shono

Publikováno v: The American journal of the medical sciences. 356(4)

Prevalence of heart failure with preserved ejection fraction (HFpEF) increases with advancing age, particularly among women. Plasma levels of B-type natriuretic peptide (BNP), a surrogate marker of heart failure, have consistently been shown to be hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21372a73cdb09d76bff13220193e0926
https://pubmed.ncbi.nlm.nih.gov/30360801

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The diabetic heart utilizes ketone bodies as an energy source

Autor: Michihiro Yoshimura, Eisaku Harada, Yuji Mizuno, Hitoshi Nakagawa, Hirofumi Yasue, Fumihito Kugimiya, Makoto Shono, Yoshinobu Morikawa

Publikováno v: Metabolism: clinical and experimental. 77

Background Diabetic heart is characterized by failure of insulin to increase glucose uptake and increasingly relies on free fatty acids (FFAs) as a source of fuel in animal models. However, it is not well known how cardiac energy metabolism is altere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37bd305f82f970affc2572253c34b510
https://pubmed.ncbi.nlm.nih.gov/29132539

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B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction - Relevance to Age-Related Left Ventricular Modeling in Japanese

Autor: Hiroyuki Maeda, Yuji Mizuno, Makoto Shono, Koichiro Kuwahara, Hirofumi Yasue, Fumihito Kugimiya, Naotsugu Yano, Eisaku Harada

Publikováno v: Circulation journal : official journal of the Japanese Circulation Society. 81(7)

BACKGROUND Heart failure (HF) with preserved ejection fraction (HFpEF) is increasing with aging of the population. Plasma levels of B-type natriuretic peptide (BNP) increase in proportion to the severity of left ventricular (LV) dysfunction. The obje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec440b6c8b247fffd8f2b7c1cc748c54
https://pubmed.ncbi.nlm.nih.gov/28381705

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Low responsiveness to thienopyridine in hemodialysis patients

Autor: Fumihito Kugimiya, Shinichi Nakamura, Shuichi Oshima, Katsuo Noda, Kenichiro Higa, Hironobu Fukushima, Makoto Shono

Publikováno v: Cardiovascular Intervention and Therapeutics. 25:18-23

We sought to evaluate whether thienopyridine low responsiveness, a predictor of stent thrombosis, is found in hemodialysis patients. We measured platelet aggregation at the site of implantation of drug-eluting stents in 333 patients with angina pecto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c88717a51a77c5a1e4b4f4484079ac
https://doi.org/10.1007/s12928-009-0002-7

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