Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Fumihito Hasebe"'
Autor:
Fumihito Hasebe1,2 fhasebe@g.fpu.ac.jp, Kazuya Adachi1, Chitose Maruyama1,2, Yoshimitsu Hamano1,2 yhamano@gfpu.ac.jp
Publikováno v:
Applied & Environmental Microbiology. Oct2024, Vol. 90 Issue 10, p1-19. 19p.
Autor:
Tomoharu Motoyama, Shogo Nakano, Fumihito Hasebe, Ryo Miyata, Shigenori Kumazawa, Noriyuki Miyoshi, Sohei Ito
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-10 (2021)
Threonine is a biosynthetic precursor to dimethylpyrazine derivatives, but the pathway by which this occurs is not fully established. Here l-throenine-3-dehydrogenase and 2-amino-3-ketobutyrate CoA ligase together are shown to convert l-threonine to
Externí odkaz:
https://doaj.org/article/0721bf5355e34425a7e030a15af7c97f
Autor:
Sumire Kurosawa, Hironori Okamura, Ayako Yoshida, Takeo Tomita, Yusuke Sone, Fumihito Hasebe, Tetsuro Shinada, Hirosato Takikawa, Saori Kosono, Makoto Nishiyama
Publikováno v:
ACS Chemical Biology. 18:385-395
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f98c757494595f801747ac77c0fd7a8
https://doi.org/10.1021/acschembio.2c00823
https://doi.org/10.1021/acschembio.2c00823
Autor:
Tomoharu Motoyama, Yuta Yamamoto, Chiharu Ishida, Fumihito Hasebe, Yui Kawamura, Yasuteru Shigeta, Sohei Ito, Shogo Nakano
Publikováno v:
ACS Omega. 7:44407-44419
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::566265e719b508cdd1479374d8730e1d
https://doi.org/10.1021/acsomega.2c06334
https://doi.org/10.1021/acsomega.2c06334
Autor:
Sumire Kurosawa, Fumihito Hasebe, Hironori Okamura, Ayako Yoshida, Kenichi Matsuda, Yusuke Sone, Takeo Tomita, Tetsuro Shinada, Hirosato Takikawa, Tomohisa Kuzuyama, Saori Kosono, Makoto Nishiyama
Publikováno v:
Journal of the American Chemical Society. 144:16164-16170
Natural products containing an aziridine ring, such as mitomycin C and azinomycin B, exhibit antitumor activities by alkylating DNA via their aziridine rings; however, the biosynthetic mechanisms underlying the formation of these rings have not yet b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4360fe5db3e2ac9985f0a1b30b52ab7c
https://doi.org/10.1021/jacs.2c07243
https://doi.org/10.1021/jacs.2c07243
Autor:
Ryo Miyata, Sohei Ito, Azusa Miyata, Chiharu Ishida, Shigenori Kumazawa, Shogo Nakano, Fumihito Hasebe
Publikováno v:
ChemCatChem. 13:5228-5235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f183a2d1aa14c948e320ee39a58e44e7
https://doi.org/10.1002/cctc.202101296
https://doi.org/10.1002/cctc.202101296
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:2404-2409
Tropane alkaloids, including clinically important hyoscyamine and scopolamine, are produced in the roots of medicinal plant species, such as Atropa belladonna, from the Solanaceae family. Recent molecular and genomic approaches have advanced our unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed19d6f1d619a4c094efe4876af47700
https://doi.org/10.1093/bbb/zbab165
https://doi.org/10.1093/bbb/zbab165
Autor:
Tomoharu, Motoyama, Yuta, Yamamoto, Chiharu, Ishida, Fumihito, Hasebe, Yui, Kawamura, Yasuteru, Shigeta, Sohei, Ito, Shogo, Nakano
Publikováno v:
ACS omega. 7(48)
The flavin-dependent amine oxidase superfamily contains various l-amino acid oxidases (LAAOs) bearing different substrate specificities and enzymatic properties. LAAOs catalyze the oxidation of the α-amino group of l-amino acids (L-AAs) to produce i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37730b742cd238712386074035166487
https://pubmed.ncbi.nlm.nih.gov/36506213
https://pubmed.ncbi.nlm.nih.gov/36506213
Autor:
Fumihito Hasebe
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 85:351-358
Methionine is a canonical amino acid. The protein MetX is a homoserine O-acyltransferase utilized in the methionine biosynthetic pathway. The metW gene is found adjacent to the metX gene in some bacteria, but its functions are unclear. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fffd12e6bf96e13292c4f691493655f
https://doi.org/10.1093/bbb/zbaa044
https://doi.org/10.1093/bbb/zbaa044
Autor:
Sumire Kurosawa, Kenichi Matsuda, Fumihito Hasebe, Makoto Nishiyama, Tomohisa Kuzuyama, Taro Shiraishi, Kazuo Shin-ya
Publikováno v:
Organic & Biomolecular Chemistry. 18:5137-5144
The 1-azabicyclo[3.1.0]hexane ring is a key moiety in natural products for biological activities against bacteria, fungi, and tumor through DNA alkylation. Ficellomycin is a dipeptide that consists of l-valine and a non-proteinogenic amino acid with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348bd06db3fa892d529a3d3c28319b2d
https://doi.org/10.1039/d0ob00339e
https://doi.org/10.1039/d0ob00339e