Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Fumihiko Kawamura"'
Autor:
Fumihiko Kawamura, Makoto Inaki, Atsushi Katafuchi, Yu Abe, Naohiro Tsuyama, Yumiko Kurosu, Aki Yanagi, Mitsunori Higuchi, Satoshi Muto, Takumi Yamaura, Hiroyuki Suzuki, Hideyoshi Noji, Shinichi Suzuki, Mitsuaki A. Yoshida, Megumi Sasatani, Kenji Kamiya, Masafumi Onodera, Akira Sakai
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract B cell derived induced pluripotent stem cells (BiPSCs) were recently established from peripheral blood B cells by the simultaneous transfection of Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) and C/EBPα using a Sendai virus vector. Here, us
Externí odkaz:
https://doaj.org/article/356c7f8b817b42dab5c51de1994d8612
Autor:
Saori Tsuji, Fumihiko Kawamura, Musashi Kubiura, Ayaka Hayashi, Tetsuya Ohbayashi, Yasuhiro Kazuki, Christophe Chesné, Mitsuo Oshimura, Masako Tada
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104123 (2014)
Human adult hepatocytes expressing CYP3A4, a major cytochrome P450 enzyme, are required for cell-based assays to evaluate the potential risk of drug-drug interactions caused by transcriptional induction of P450 enzymes in early-phase drug discovery a
Externí odkaz:
https://doaj.org/article/49c39f1fa3b24521b3a0c4238e38bbb7
Autor:
Shota Okuyama1, Fumihiko Kawamura1,2, Musashi Kubiura1, Saori Tsuji3, Mitsuhiko Osaki3, Hiroyuki Kugoh2,3, Mitsuo Oshimura3, Yasuhiro Kazuki2,3, Masako Tada1 masako.tada@sci.toho-u.ac.jp
Publikováno v:
Pharmacology Research & Perspectives. Oct2020, Vol. 8 Issue 5, p1-13. 13p.
Autor:
Fumihiko Kawamura, Yasuhiro Kazuki, Mitsuo Oshimura, Masako Tada, Hiroyuki Kugoh, Shota Okuyama, Mitsuhiko Osaki, Musashi Kubiura, Saori Tsuji
Publikováno v:
Pharmacology Research & Perspectives
The fields of drug discovery and regenerative medicine require large numbers of adult human primary hepatocytes. For this purpose, it is desirable to use hepatocyte‐like cells (HLCs) differentiated from human pluripotent stem cells (PSCs). Prematur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c12e78442789bda12328f2bc4ea8a1
https://doi.org/10.1002/prp2.642
https://doi.org/10.1002/prp2.642
Autor:
Takafumi Ueyama, Keiko Ooeda, Mao Yamashita, Musashi Kubiura-Ichimaru, Shota Okuyama, Masako Tada, Fumihiko Kawamura, Akari Mine, Saori Tsuji
Publikováno v:
Pharmacology Research & Perspectives
Cytochrome P450 enzymes (CYP) function in drug metabolism in the liver. To evaluate numerous drug candidates, a high‐content screening (HCS) system with hepatocyte‐like cells (HLCs) that can replace adult human hepatocytes is required. Human hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0190cb3f2b7843375057ab9931c10b6a
https://pubmed.ncbi.nlm.nih.gov/32955797
https://pubmed.ncbi.nlm.nih.gov/32955797
Autor:
Yukari Yanai, Misaki Sugai, Fumihiko Kawamura, Yu Abe, Atsushi Katafuchi, Akira Sakai, Kenji Kamiya, Naohiro Tsuyama, Aki Yanagi
Publikováno v:
Oncology Letters
Chromosomal translocation is a key process in the oncogenic transformation of somatic cells. Previously, artificial induction of chromosomal translocation was performed using homologous recombination-mediated loxP labeling of target regions followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198b080db7e68853e9bbd9aa3ff90ed8
https://doi.org/10.3892/ol.2019.10303
https://doi.org/10.3892/ol.2019.10303
Autor:
Jun Ohsugi, Hiroshi Yokouchi, Takashi Ishida, Tomoko Inamasu, Akira Sakai, Risa Ujiie, Fumihiko Kawamura, Yumiko Kurosu, Yu Abe, Atsushi Katafuchi, Nagisa Kato, Hiroyuki Suzuki, Tomisato Miura, Tetsuo Ishikawa, Naohiro Tsuyama, Kazuei Ogawa, Satoshi Muto, Fumio Shishido, Hideyoshi Noji, Takashi Ohba, Kenji Kamiya, Kenya Kanazawa, Mitsuaki A. Yoshida
Publikováno v:
Journal of Radiation Research
We recently reported an increase in dicentric chromosome (DIC) formation after a single computed tomography (CT) scan (5.78–60.27 mSv: mean 24.24 mSv) and we recommended analysis of 2000 metaphase cells stained with Giemsa and centromere-FISH for d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b91bc40f108624dcb4ab348e3493f33
https://doi.org/10.1093/jrr/rrv090
https://doi.org/10.1093/jrr/rrv090
Autor:
Ryoichi Nagatomi, Hiroki Umeda, Yoichi Haga, Shin-ichi Izumi, Shigeaki Okumura, Yosuke Hara, Yukio Katori, Tatsuya Uechi, Fumihiko Kawamura, Hirofumi Taki
Publikováno v:
HealthCom
We investigate the potential of through-transmission ultrasound in noninvasive aspiration detection for bedside rehabilitation. In the present study, we used through- transmission ultrasound to investigate the waveform change in received signals caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44a73ef8591fbad5396cf4e6b3444bc
https://doi.org/10.1109/healthcom.2018.8531081
https://doi.org/10.1109/healthcom.2018.8531081
Autor:
Keiko Ooeda, Musashi Kubiura-Ichimaru, Saori Tsuji, Shota Okuyama, Mao Yamashita, Akari Mine, Fumihiko Kawamura, Takafumi Ueyama, Masako Tada
Publikováno v:
Pharmacology Research & Perspectives; Oct2020, Vol. 8 Issue 5, p1-12, 12p
Autor:
Atsushi Katafuchi, Makoto Inaki, Fumihiko Kawamura, Akira Sakai, Shinichi Suzuki, Yu Abe, Takumi Yamaura, Megumi Sasatani, Kenji Kamiya, Yumiko Kurosu, Hiroyuki Suzuki, Satoshi Muto, Hideyoshi Noji, Naohiro Tsuyama, Mitsunori Higuchi, Mitsuaki A. Yoshida, Aki Yanagi, Masafumi Onodera
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
B cell derived induced pluripotent stem cells (BiPSCs) were recently established from peripheral blood B cells by the simultaneous transfection of Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) and C/EBPα using a Sendai virus vector. Here, using a dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf69ea8131e39af30d1089d42b2d56e9
https://pubmed.ncbi.nlm.nih.gov/28490810
https://pubmed.ncbi.nlm.nih.gov/28490810