Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Fumihiko Hato"'
Autor:
Fumihiko Hato, Kazuo Ikeda, Hideki Fujii, Yuji Nakajima, Kohji Otogawa, Yoshihiro Ikura, Kazuki Nakatani, Kohji Kinoshita, Makiko Ueda, Tetsuo Arakawa, Masahide Sakabe, Ryoko Shiga, Norifumi Kawada
Publikováno v:
The American Journal of Pathology. 170:967-980
Nonalcoholic steatohepatitis (NASH) is a progressive fibrotic disease, the pathogenesis of which has not been fully elucidated. Here, we report a molecular aspect of this disease elucidated using rabbits fed a cholesterol-rich high-fat diet and exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc66c8e775e027aa6a096ebe864f138b
https://doi.org/10.2353/ajpath.2007.060441
https://doi.org/10.2353/ajpath.2007.060441
Autor:
Haruo Shintaku, Kazuo Kobayashi, Yoshiki Nishizawa, Tatsuji Takahashi, Nagatoshi Fujiwara, Masaaki Inaba, Nobuji Maeda, Seiichi Kitagawa, Fumihiko Hato
Publikováno v:
Microvascular Research. 73:29-34
The reactivity of endothelial cells (ECs) to proinflammatory cytokines is critically important for the pathogenesis of vascular diseases. Here, we studied functional alterations of human ECs during culture under a confluent condition; i.e., the alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e198acbfcc74ace30b62afc84894963a
https://doi.org/10.1016/j.mvr.2006.08.002
https://doi.org/10.1016/j.mvr.2006.08.002
Autor:
Hidekazu Yukioka, Noboru Kato, Tadatomo Kodama, Takayuki Kato, Seiichi Kitagawa, Fumihiko Hato
Publikováno v:
Internal Medicine. 46:699-704
Objective To determine whether the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) associated with systemic inflammatory response syndrome (SIRS) can be predicted by the plasma neutrophil elastase level. Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298228703ffc82d583ed377c86b2456e
https://doi.org/10.2169/internalmedicine.46.6182
https://doi.org/10.2169/internalmedicine.46.6182
Autor:
Fumihiko Hato, Sayuri Masuda, Haruo Kutsuna, Seiichi Kitagawa, Masayuki Hino, Mika Nakamae-Akahori, Erina Sakamoto, Yoshiki Nishizawa, Takayuki Kato
Publikováno v:
Immunology. 119:393-403
The effect of granulocyte colony-stimulating factor (G-CSF) on human neutrophil motility was studied using videomicroscopy. Stimulation of neutrophils with G-CSF resulted in enhanced motility with morphological change and increased adherence. Enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9cd62a9820c95e2da4bb01be84a669
https://doi.org/10.1111/j.1365-2567.2006.02448.x
https://doi.org/10.1111/j.1365-2567.2006.02448.x
Publikováno v:
Ensho Saisei. 25:525-531
Human neutrophils undergo spontaneous apoptosis, and spontaneous neutrophil apoptosis is delayed in the presence of various inflammatory cytokines, including G-CSF, GM-CSF, IFN-α and IFN-γ. These cytokines exert the antiapoptotic effect on human ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6285832e11f2d6dc6bc08602edf33721
https://doi.org/10.2492/jsir.25.525
https://doi.org/10.2492/jsir.25.525
Autor:
Haruo Kutsuna, Erina Sakamoto, Takayuki Kato, Fumihiko Hato, Seiichi Kitagawa, Akiko Kimura-Eto
Publikováno v:
Journal of Biological Chemistry. 279:31076-31080
Four isoforms (alpha, beta, gamma, and delta) have been identified for signal transducer and activator of transcription 3 (STAT3). It has been reported that STAT3gamma, which is derived from STAT3alpha by limited proteolysis during granulocytic diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e316bd7bdac070856af0de0e067e2627
https://doi.org/10.1074/jbc.m400637200
https://doi.org/10.1074/jbc.m400637200
Autor:
Noriko Kamata, Akiko Kimura-Eto, Erina Sakamoto, Taro Hasegawa, Fumihiko Hato, Masayuki Hino, Saori Nishiki, Seiichi Kitagawa
Publikováno v:
American Journal of Physiology-Cell Physiology. 286:C1302-C1311
Lipopolysaccharide (LPS) induced tumor necrosis factor (TNF)-α production in human monocytes, which was dependent on activation of extracellular signal-regulated kinase (ERK), p38, c-Jun NH2-terminal kinase (JNK), and nuclear factor (NF)-κB. LPS-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a93321937e35cd38d34562df664ce5
https://doi.org/10.1152/ajpcell.00387.2003
https://doi.org/10.1152/ajpcell.00387.2003
Autor:
Noriko Kamata, Seiichi Kitagawa, Kenichi Suzuki, Masamitsu Ishii, Kensaku Mizuno, Takayuki Kato, Hiromi Kobayashi, Fumihiko Hato, Haruo Kutsuna
Publikováno v:
American Journal of Physiology-Cell Physiology. 286:C55-C64
Stimulation of human neutrophils with tumor necrosis factor-α (TNF), granulocyte-macrophage colony-stimulating factor (GM-CSF), or granulocyte CSF (G-CSF) resulted in decreased fluorescence intensity of FITC-phalloidin (actin depolymerization) and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9e7d541d73c504f152fe5007ba727d
https://doi.org/10.1152/ajpcell.00131.2003
https://doi.org/10.1152/ajpcell.00131.2003
Autor:
Fumihiko Hato, Seiichi Kitagawa, Yasuhiro Fujiwara, Nobuhide Oshitani, Kazuhide Higuchi, Takayuki Matsumoto, Tetsuo Arakawa, Kenji Watanabe
Publikováno v:
Clinical and Vaccine Immunology. 10:856-861
Dysregulation of immune responses to intestinal exogenous antigens contributes to the pathogenesis of inflammatory bowel disease, but the specific antigen responsible for the pathogenesis of inflammatory bowel disease is unknown. We measured serum an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32aa3833734391b57b8bdaf0cef6a334
https://doi.org/10.1128/cdli.10.5.856-861.2003
https://doi.org/10.1128/cdli.10.5.856-861.2003
Publikováno v:
International Journal of Hematology. 77:253-258
Stimulation of human neutrophils with granulocyte-macrophage colony-stimulating factor (GM-CSF) or tumor necrosis factor-alpha (TNF) results in increased superoxide (O2-) release and adherence. O2- release and adherence are dependent on activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c20788e39e373300c13bbb00846d94
https://doi.org/10.1007/bf02983782
https://doi.org/10.1007/bf02983782