Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Fumihiko, Horio"'
Autor:
Masakazu Nambo, Taeko Nishiwaki-Ohkawa, Akihiro Ito, Zachary T. Ariki, Yuka Ito, Yuuki Kato, Muhammad Yar, Jacky C. -H. Yim, Emily Kim, Elizabeth Sharkey, Keiko Kano, Emi Mishiro-Sato, Kosuke Okimura, Michiyo Maruyama, Wataru Ota, Yuko Furukawa, Tomoya Nakayama, Misato Kobayashi, Fumihiko Horio, Ayato Sato, Cathleen M. Crudden, Takashi Yoshimura
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-14 (2024)
Abstract Background Thyroid hormones (TH) regulate the basal metabolic rate through their receptors THRα and THRβ. TH activates lipid metabolism via THRβ, however, an excess amount of TH can lead to tachycardia, bone loss, and muscle wasting throu
Externí odkaz:
https://doaj.org/article/30f4577426754f67803518bc6b5bc019
Autor:
Misato Kobayashi, Fumi Kanbe, Reika Ishii, Hiroki Tsubouchi, Kana Hirai, Yuki Miyasaka, Tamio Ohno, Hiroaki Oda, Saiko Ikeda, Hirokazu Katoh, Kenji Ichiyanagi, Akira Ishikawa, Atsushi Murai, Fumihiko Horio
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract High serum levels of triglycerides (TG) and low levels of high-density lipoprotein cholesterol (HDL-C) increase the risk of coronary heart disease in humans. Herein, we first reported that the C3H/HeNSlc (C3H-S) mouse, a C3H/HeN-derived subs
Externí odkaz:
https://doaj.org/article/5f8aa6917a3d4aa692c883570dd21b94
Autor:
Mayuko Okamoto, Ryo Sasaki, Koki Ikeda, Kasumi Doi, Fumiya Tatsumi, Kenzi Oshima, Takaaki Kojima, Shusei Mizushima, Keisuke Ikegami, Takashi Yoshimura, Kyohei Furukawa, Misato Kobayashi, Fumihiko Horio, Atsushi Murai
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Maternal immunoglobulin transfer plays a key role in conferring passive immunity to neonates. Maternal blood immunoglobulin Y (IgY) in avian species is transported to newly-hatched chicks in two steps: 1) IgY is transported from the maternal circulat
Externí odkaz:
https://doaj.org/article/02025fa47e8746738a7fcdf50e4d93ce
Autor:
Misato Kobayashi, Hironori Ueda, Naru Babaya, Michiko Itoi-Babaya, Shinsuke Noso, Tomomi Fujisawa, Fumihiko Horio, Hiroshi Ikegami
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Both genetic and environmental factors contribute to type 2 diabetes development. We used consomic mice established from an animal type 2 diabetes model to identify susceptibility genes that contribute to type 2 diabetes developme
Externí odkaz:
https://doaj.org/article/2e6d7f5f2c5c4ad9bd2dcc728e9b01c3
Publikováno v:
Journal of Nutritional Science and Vitaminology. 68:481-487
We previously demonstrated that ascorbic acid (AsA) deficiency, caused by an AsA-free diet, induces inflammatory changes in the liver and intestine of osteogenic disorder Shionogi (ODS) rats that cannot synthesize AsA. However, whether low AsA intake
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf96fabb889d192f7ff6f21db4bc8a90
https://doi.org/10.3177/jnsv.68.481
https://doi.org/10.3177/jnsv.68.481
Autor:
Tomomi Masuya, Miyako Suzuki, Junko Tsujimura, Shinsaku Kanamori, Yuki Miyasaka, Tamio Ohno, Atsushi Murai, Fumihiko Horio, Misato Kobayashi
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233087 (2020)
Nonalcoholic fatty liver disease (NAFLD) is a pathological condition caused by excess triglyceride deposition in the liver. The SMXA-5 severe fatty liver mouse model has been established from the SM/J and A/J strains. To explore the genetic factors i
Externí odkaz:
https://doaj.org/article/4dcac94e2d4e4f19bd44115ad1c0000f
Autor:
Yuki Miyasaka, Takeshi Kobayashi, Naoya Gotoh, Masako Kuga, Misato Kobayashi, Fumihiko Horio, Katsunori Hashimoto, Tsutomu Kawabe, Tamio Ohno
Publikováno v:
Mammalian Genome. 34:32-43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e56f1cf1b6e42c0e86c57b3d55c40cd
https://doi.org/10.1007/s00335-022-09966-9
https://doi.org/10.1007/s00335-022-09966-9
Autor:
Tamio, Ohno, Yuki, Miyasaka, Kanta, Yoshida, Misato, Kobayashi, Fumihiko, Horio, Norihide, Yokoi, Masashi, Mizuno, Hiroshi, Ikegami
Publikováno v:
Experimental Animals. 71:510-518
Various mouse models of type 2 diabetes have been established, but few of these show early onset and persistent hyperglycemia. We have established a congenic mouse strain (NSY.B6-Tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ee47d447851109c4bf39eac06edc28
https://doi.org/10.1538/expanim.22-0061
https://doi.org/10.1538/expanim.22-0061
Publikováno v:
Poultry Science
Poultry Science, Vol 99, Iss 4, Pp 1914-1920 (2020)
Poultry Science, Vol 99, Iss 4, Pp 1914-1920 (2020)
In avian species, maternal immunoglobulin Y (IgY) is transferred from the blood to the yolks of maturing oocytes; however, the mechanism underlying this transfer is unknown. To gain insight into the mechanisms of maternal IgY transfer into egg yolks,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290c4047cfecac6277b707991cd73d65
https://doi.org/10.1016/j.psj.2019.11.045
https://doi.org/10.1016/j.psj.2019.11.045
Publikováno v:
Journal of Nutritional Science and Vitaminology. 66:19-23
Using rats, we previously found that vitamin C deficiency increases serum levels of interleukin-6 (IL-6) and glucocorticoid, and changes the gene expression of acute phase proteins (APP) in the liver. However, it remains unclear how vitamin C deficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebebad811c7de38e0d42dae49104396a
https://doi.org/10.3177/jnsv.66.19
https://doi.org/10.3177/jnsv.66.19