Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Fumihide Ishibashi"'
Autor:
Yoshiyasu Yabusaki, Toshiro Niwa, Masanao Katagiri, Akira Kageyama, Kae Kishimoto, Fumihide Ishibashi
Publikováno v:
Drug Metabolism and Disposition. 30:931-936
The amino acid residues affecting the substrate specificity of human cytochrome P450 CYP2C9 and CYP2C19 for their metabolic activities were investigated using chimeras and mutant enzymes, which were constructed by replacing the corresponding residues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f7e657d6e15ebba12bc6882f426e0a
https://doi.org/10.1124/dmd.30.8.931
https://doi.org/10.1124/dmd.30.8.931
Autor:
Toshiro Niwa, Kae Kishimoto, Megumi Fujimoto, Yumi Maekawa, Fumihide Ishibashi, Masanao Katagiri, Yoshiyasu Yabusaki
Publikováno v:
Biological and Pharmaceutical Bulletin. 25:235-238
Effect of nonylphenol on aminopyrine N-demethylase activity, a typical drug-metabolizing enzyme activity, by ten kinds of human hepatic cytochrome P450s (CYP) and on progesterone 17alpha-hydroxylase activity by steroidogenic CYP17 was investigated. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bf62d2b7b198a6b966be2bf6b703f9
https://doi.org/10.1248/bpb.25.235
https://doi.org/10.1248/bpb.25.235
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 63:1988-1990
We examined the effects of methanol and temperature on the reactivity of monoclonal antibodies specific to the insecticide etofenprox. When the antigen-antibody reaction was done at 4 degrees C in 10% methanol, the sensitivity in the enzyme immunoass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e004a6732fb5a0cbb0bd920439cf5d6d
https://doi.org/10.1271/bbb.63.1988
https://doi.org/10.1271/bbb.63.1988
Autor:
Yoshiyasu Yabusaki, Toshiro Niwa, Masanao Katagiri, Megumi Fujimoto, Kae Kishimoto, Fumihide Ishibashi
Publikováno v:
Biologicalpharmaceutical bulletin. 24(9)
The metabolism of bisphenol A (BPA) was determined for 11 forms of human hepatic cytochromes P450 (CYPs) expressed in the yeast Saccharomyces cerevisiae and for human steroidogenic CYP17 expressed in Escherichia coli. Additionally, the effect of BPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae232da94aa0f0e0afa80d69a8ad3fab
https://pubmed.ncbi.nlm.nih.gov/11558570
https://pubmed.ncbi.nlm.nih.gov/11558570
Autor:
Yoshiyasu Yabusaki, Miki Tsutsui, Masanao Katagiri, Fumihide Ishibashi, Toshiro Niwa, Kae Kishimoto
Publikováno v:
Biologicalpharmaceutical bulletin. 23(4)
Effect of bisphenol A on drug-metabolizing enzyme activities by human hepatic cytochrome P450s (CYP) was investigated. We measured aminopyrine N-demethylation by eleven kinds of cDNA-expressed CYPs. CYP2C19 and CYP2B6 catalyzed most efficiently the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8ab70442c37e37b99820a111f4fe64
https://pubmed.ncbi.nlm.nih.gov/10784435
https://pubmed.ncbi.nlm.nih.gov/10784435
Autor:
Kayo Tatsuta, Fumihide Ishibashi, Kazunori Ishimura, Hiromichi Yokoi, Susumu Imaoka, Nobutake Matsuo, Masanao Katagiri, Norio Kagawa, Yoshihiko Funae, Keiko Honma
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 64(1-2)
Steroid hydroxylase cytochrome P450c17 has been previously purified from microsomal fractions of immature rat livers. In this study, we investigated the expression of P450c17 in rat livers to understand a role of steroidogenesis in the extrasteroidog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54284540245a0e990702e259baa64672
https://pubmed.ncbi.nlm.nih.gov/9569017
https://pubmed.ncbi.nlm.nih.gov/9569017
Autor:
Takenobu Kamada, Yutaka Kishida, Motoaki Shichiri, Fumihide Ishibashi, Fujiya Furuyama, Norio Hayashi, Nobuhiro Sato, Bunji Hagihara, Takakatsu Matsumura, Hiroshi Abe, Toshihiko Suematsu
Publikováno v:
The Journal of Biochemistry. 84:117-125
The changes in liver mitochondrial respiratory activities and cytochrome concentrations were investigated when cadmium chloride was administered orally to adult, young, and ethionine-fed rats. Following a seven-day administration of 30 ppm cadmium in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dddb2ac57d4ec52871be4eb7e057c92d
https://doi.org/10.1093/oxfordjournals.jbchem.a132100
https://doi.org/10.1093/oxfordjournals.jbchem.a132100
Autor:
Takeo Nashima, Fumihide Ishibashi, Keiko Yamamoto, Shigeko Sasaki, Yoshimi Kitagawa, Masako Yoshikawa, Yoshinori Ichihara, Junko Nishino, Atsuko Matsuoka, Ikuko Kobayashi
Publikováno v:
Bulletin of the Chemical Society of Japan. 59:73-76
Each geometrical isomer of various substituted phenylhydrazones of ethyl pyruvate and 2,4-dinitrophenylhydrazones of some α-keto esters was isolated in a pure state. Partial isomerizations of the E-isomers of the former hydrazones to the Z-isomers t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecc68e3720486840f93cdcf3e4e1d1fb
https://doi.org/10.1246/bcsj.59.73
https://doi.org/10.1246/bcsj.59.73
Autor:
Nobuhiro Sato, Toshihiko Suematsu, Fujiya Furuyama, Fumihide Ishibashi, Takenobu Kamada, Bunji Hagihara
Publikováno v:
Kanzo. 16:841-850
ミトコンドリア(Mt)の酸化的リン酸化反応の抑制物質であるカドミウム(Cd)を成熟ラット群,幼若群,エチオニンで肝障害を惹起した群に投与した場合の肝臓Mt機能を検索し,組織障害とMtのエ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687587bd4f7e3a72a08923e6cb58a01e
https://doi.org/10.2957/kanzo.16.841
https://doi.org/10.2957/kanzo.16.841