Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Fumiharu, Ohka"'
Autor:
Junya Yamaguchi, Fumiharu Ohka, Masafumi Seki, Kazuya Motomura, Shoichi Deguchi, Yoshiki Shiba, Yuka Okumura, Yuji Kibe, Hiroki Shimizu, Sachi Maeda, Yuhei Takido, Ryo Yamamoto, Akihiro Nakamura, Kennosuke Karube, Ryuta Saito
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-7 (2024)
Abstract Mutations in the isocitrate dehydrogenase (IDH) gene are recognized as the key drivers in the oncogenesis of astrocytoma and oligodendroglioma. However, the significance of IDH mutation in tumor maintenance and malignant transformation has n
Externí odkaz:
https://doaj.org/article/f9f5ded7c6c5412cb0f008ce4aa78f77
Publikováno v:
Neurologia Medico-Chirurgica, Vol 64, Iss 7, Pp 253-260 (2024)
Brain tumor-related epilepsy (BTRE) is a complication that significantly impairs the quality of life and course of treatment of patients with brain tumors. Several recent studies have shed further light on the mechanisms and pathways by which genes a
Externí odkaz:
https://doaj.org/article/1834fe6403ac4616871895d75be4b997
Autor:
Yuji Kibe, Fumiharu Ohka, Kosuke Aoki, Junya Yamaguchi, Kazuya Motomura, Eiji Ito, Kazuhito Takeuchi, Yuichi Nagata, Satoshi Ito, Nobuhiko Mizutani, Yoshiki Shiba, Sachi Maeda, Tomohide Nishikawa, Hiroki Shimizu, Ryuta Saito
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Li-Fraumeni syndrome (LFS) is an autosomal dominant tumor predisposition syndrome caused by heterozygous germline mutations or deletions in the TP53 tumor suppressor gene. Central nervous system tumors, such as choroid plexus tumors, medullo
Externí odkaz:
https://doaj.org/article/8a4831412d03486798dd6a0ea60ec8dd
Autor:
Yutaro Fuse, Yoshitaka Nagashima, Hiroshi Nishiwaki, Fumiharu Ohka, Yusuke Muramatsu, Yoshio Araki, Yusuke Nishimura, Jumpei Ienaga, Tetsuya Nagatani, Yukio Seki, Kazuhiko Watanabe, Kinji Ohno, Ryuta Saito
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Chronic subdural hematoma (CSDH) often causes neurological deterioration and is treated with hematoma evacuation. This study aimed to assess the feasibility of various machine learning models to preoperatively predict the functional outcome
Externí odkaz:
https://doaj.org/article/8c1145fbaf614d80b6b0ebb5f54641b6
Autor:
Miho M. Suzuki, Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, Akira Mamiya, Yuji Kibe, Tatsunori Nishimura, Fumiharu Ohka, Ryuta Saito, Shinya Sato, Junya Kobayashi, Ryoji Yao, Kanjiro Miyata, Kazunori Kataoka, Hiroshi I. Suzuki, Yutaka Kondo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Oncogene-induced DNA replication stress (RS) and consequent pathogenic R-loop formation are known to impede S phase progression. Nonetheless, cancer cells continuously proliferate under such high-stressed conditions through incompletely unde
Externí odkaz:
https://doaj.org/article/3a39adce796d43a99a5582287d10e0b2
Autor:
Junya Yamaguchi, Fumiharu Ohka, Chalise Lushun, Kazuya Motomura, Kosuke Aoki, Kazuhito Takeuchi, Yuichi Nagata, Satoshi Ito, Nobuhiko Mizutani, Masasuke Ohno, Noriyuki Suzaki, Syuntaro Takasu, Yukio Seki, Takahisa Kano, Kenichi Wakabayashi, Hirofumi Oyama, Shingo Kurahashi, Kuniaki Tanahashi, Masaki Hirano, Hiroyuki Shimizu, Yotaro Kitano, Sachi Maeda, Shintaro Yamazaki, Toshihiko Wakabayashi, Yutaka Kondo, Atsushi Natsume, Ryuta Saito
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 7116-7126 (2023)
Abstract Background Rituximab, high‐dose methotrexate (HD‐MTX), procarbazine and vincristine (R‐MPV), has significantly prolonged the survival of patients with primary central nervous system lymphoma (PCNSL), but predictive factors for response
Externí odkaz:
https://doaj.org/article/9032b57cfdb94eec8ed1c32a18c58b14
Autor:
Yuji Kibe, Kazuya Motomura, Fumiharu Ohka, Kosuke Aoki, Hiroyuki Shimizu, Junya Yamaguchi, Tomohide Nishikawa, Ryuta Saito
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Isocitrate dehydrogenase wild-type (IDHwt) diffuse astrocytomas feature highly infiltrative patterns, such as a gliomatosis cerebri growth pattern with widespread involvement. Among these tumors, localized IDHwt histologically diffuse astroc
Externí odkaz:
https://doaj.org/article/beeff8d37e5b4693a460339ccf8eee1a
Autor:
Yoshitaka Nagashima, Yusuke Nishimura, Kaoru Eguchi, Junya Yamaguchi, Shoichi Haimoto, Fumiharu Ohka, Masakazu Takayasu, Ryuta Saito
Publikováno v:
Neurospine, Vol 19, Iss 2, Pp 262-271 (2022)
The study of genetic alterations and molecular biology in central nervous system (CNS) tumors has improved the accuracy of estimations of patient prognosis and tumor categorization. Therefore, the updated 2021 World Health Organization (WHO) classifi
Externí odkaz:
https://doaj.org/article/0482ffc89949418db1b9828f4f3b275d
Autor:
Yuji Kibe, Kuniaki Tanahashi, Kazuhiro Ohtakara, Yuka Okumura, Fumiharu Ohka, Kazuhito Takeuchi, Yuichi Nagata, Kazuya Motomura, Sho Akahori, Akihiro Mizuno, Hiroo Sasaki, Hiroyuki Shimizu, Junya Yamaguchi, Tomohide Nishikawa, Kenji Yokota, Ryuta Saito
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Eccrine spiradenocarcinoma (SC), also known as malignant eccrine spiradenoma, is a rare malignant cutaneous adnexal neoplasm arising from long-standing benign eccrine spiradenoma. Malignant skin tumors rarely show direct intracran
Externí odkaz:
https://doaj.org/article/151848dd591046cca63b5d013900407b
Autor:
Hirotaka Niwa, Takenori Kato, Toshinori Hasegawa, Kyoko Kuwabara, Fumiharu Ohka, Junko Hirato, Shoh Sasaki, Koichi Ichimura, Takako Yoshioka, Takehiro Naito, Akihiro Mizuno, Akinori Kageyama, Hiroyuki Oishi, Ryuta Saito
Publikováno v:
Journal of Neurosurgery Case Lessons; Oct2024, Vol. 86 Issue 15, p1-6, 6p