Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Fumie Tanzawa"'
Autor:
Makoto Nakagawa, Masayuki Yamaguchi, Makoto Endo, Yukino Machida, Ayuna Hattori, Fumie Tanzawa, Shinji Tsutsumi, Issay Kitabayashi, Akira Kawai, Fumihiko Nakatani
Publikováno v:
Journal of Bone Oncology, Vol 34, Iss , Pp 100430- (2022)
Background: Chondrosarcoma is a common form of malignant bone tumor with limited treatment options. Approximately half of chondrosarcomas harbor gain-of-function mutations in isocitrate dehydrogenase (IDH), and mutant IDH produces 2-hydroxyglutarate
Externí odkaz:
https://doaj.org/article/2608c96933974fcbb235adc9d90b84cb
Autor:
Ken Ichi Yoshida, Isao Yasumatsu, Takeshi Isoyama, Yumi Matsui, Fumie Tanzawa, Yutaka Ikeno, Shin Iimura, Hiroyuki Hanzawa, Takako Nawano, Osamu Ubukata, Hajime Fukano
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 74:156-160
Mitogen-activated protein kinase (MAPK)-interacting kinases 1 (Mnk1) and 2 (Mnk2) modulate translation initiation through the phosphorylation of eukaryotic translation initiation factor 4E, which promotes tumorigenesis. However, Mnk1 and Mnk2 are dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d1ccd2351348da24a25e43fba98d27
https://doi.org/10.1107/s2053230x18002108
https://doi.org/10.1107/s2053230x18002108
Autor:
Masaki Kiga, Kanae Suzuki, Isao Yasumatsu, Shinichi Kurakata, Etsu Tashiro, Yuji Nakamura, Tomoyuki Shibata, Tomoki Echigo, Fumie Tanzawa, Hayato Iwadare, Shiho Iwasaki, Ayako Nakayama, Fumi Inaba, Masaya Imoto, Kosaku Fujiwara, Yukiko Sasazawa
Publikováno v:
Anti-Cancer Drugs. 23:119-130
The mitogen-activated protein kinase (MAPK) signal pathway plays a central role in regulating tumor cell proliferation, survival, and differentiation. The components of this pathway, Ras/Raf/MEK/ERK, are frequently activated in human cancers. Targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd33c0d79c55a698658ad28824012b2
https://doi.org/10.1097/cad.0b013e32834c6a33
https://doi.org/10.1097/cad.0b013e32834c6a33
Autor:
Shinichi Miura, Mitsuhashi Yoshihiro, Kazuo Tanaka, Shinichi Kurakata, Takahiro Shibayama, Fumie Tanzawa, Akihiro Tomida, Tatsuji Nomura, Kenji Hanaoka, Takashi Tsuruo, Akira Matsuda, Yusuke Wataya, Masako Suzuki, Tomowo Kobayashi, Kaneko Masakatsu, Haruo Iwabuchi, Tomoko Ikeda, Akihiko Nakagawa, Masashi Hisaoka, Takuma Sasaki
Publikováno v:
International Journal of Cancer. 82:226-236
We have studied the antitumor activity and the novel DNA-self-strand-breaking mechanism of CNDAC (1-(2-C-cyano-2-deoxy-β-d-arabino-pentofuranosyl)cytosine) and its N4-palmitoyl derivative (CS-682). In vitro, CS-682 showed strong cytotoxicity against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b126e9cfe20b3e9ea24d4d66440e55c
https://doi.org/10.1002/(sici)1097-0215(19990719)82:2<226::aid-ijc13>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19990719)82:2<226::aid-ijc13>3.0.co
Autor:
Toshinori Agatsuma, Noriyuki Hayashi, Ichiro Hayakawa, Youko Oda, Fumie Tanzawa, Kumiko Koyama, Yuichi Sugano, Masao Yoshida, Shiho Iwasaki, Hidehiko Furukawa, Shinichi Kurakata
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(14)
Based on 2-methyl-4-nitro-2H-pyrazole-3-carboxylic acid[2-(cyclohexanecarbonylamino)benzothiazol-6-yl]amide (1), which shows selective cytotoxicity against tumorigenic cell lines, 2,6-dichloro-N-[2-(cyclopropanecarbonylamino)benzothiazol-6-yl]benzami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c891bec0225a65f3adf9fac57a54095
https://pubmed.ncbi.nlm.nih.gov/15955697
https://pubmed.ncbi.nlm.nih.gov/15955697
Autor:
Masaki Kiga, Shinichi Kurakata, Fumie Tanzawa, Kosaku Fujiwara, Ayako Nakayama, Tomoki Echigo, Isao Yasumatsu, Masaya Imoto, Hayato Iwadare, Tomoyuki Shibata, Shiho Iwasaki, Fumi Inaba, Etsu Tashiro, Yuji Nakamura, Kanae Suzuki, Yukiko Sasazawa
Publikováno v:
Molecular Cancer Therapeutics. 10:B133-B133
The mitogen-activated protein kinase (MAPK) signal pathway plays a central role in regulating tumor cell proliferation, survival, and differentiation. The components of this pathway, Ras/Raf/MEK/ERK, are frequently activated in human cancers. Targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5707a065f88b815960de32c97f953b
https://doi.org/10.1158/1535-7163.targ-11-b133
https://doi.org/10.1158/1535-7163.targ-11-b133
Autor:
Abdelbasset, Walid Kamal1,2 (AUTHOR), Sultan, Mohammed Q.3 (AUTHOR) Mohammed.Q.Sultan.22@gmail.com, Alkaim, Ayad F.4 (AUTHOR), Abdullaevich Ashurov, Tulkin5 (AUTHOR), Altimari, Usama S.6 (AUTHOR), Hussein, Baydaa Abed7 (AUTHOR), Mustafa, Yasser Fakri8 (AUTHOR) yasserfakrimustafa@gmail.com, Hammid, Ali Thaeer9 (AUTHOR)
Publikováno v:
Polycyclic Aromatic Compounds. 2023, Vol. 43 Issue 9, p7970-7978. 9p.
Autor:
Matsui, Yumi1, Yasumatsu, Isao1, Ikeno, Yutaka1, Nawano, Takako1, Fukano, Hajime1, Ubukata, Osamu1, Hanzawa, Hiroyuki1, Yoshida, Ken-ichi2, Iimura, Shin2, Tanzawa, Fumie2, Isoyama, Takeshi2
Publikováno v:
Acta Crystallographica: Section F, Structural Biology Communications. Mar2018, Vol. 74 Issue 3, p156-160. 4p.
Autor:
Numata, Masashi1 (AUTHOR), Haginoya, Noriyasu2 (AUTHOR), Shiroishi, Machiko1 (AUTHOR), Hirata, Tsuyoshi2 (AUTHOR), Sato-Otsubo, Aiko3,4 (AUTHOR), Yoshikawa, Kenji1 (AUTHOR), Takata, Yoshimi1 (AUTHOR), Nagase, Reina1 (AUTHOR), Kashimoto, Yoshinori2 (AUTHOR), Suzuki, Makoto2 (AUTHOR), Schulte, Nina5 (AUTHOR), Polier, Gernot5 (AUTHOR), Kurimoto, Akiko1 (AUTHOR), Tomoe, Yumiko1 (AUTHOR), Toyota, Akiko1 (AUTHOR), Yoneyama, Tomoko2 (AUTHOR), Imai, Emi2 (AUTHOR), Watanabe, Kenji1 (AUTHOR), Hamada, Tomoaki1 (AUTHOR), Kanada, Ryutaro1 (AUTHOR)
Publikováno v:
Cancer Cell International. 2/25/2023, Vol. 23 Issue 1, p1-16. 16p.
Autor:
Abdelbasset, Walid Kamal, Sultan, Mohammed Q., Alkaim, Ayad F., Abdullaevich Ashurov, Tulkin, Altimari, Usama S., Hussein, Baydaa Abed, Mustafa, Yasser Fakri, Hammid, Ali Thaeer
Publikováno v:
Polycyclic Aromatic Compounds; 2023, Vol. 43 Issue 9, p7970-7978, 9p