Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fumie Ohtomo"'
Autor:
Sarasa Isobe, Kazunori Shimada, Koji Akita, Motoaki Sano, Tohru Minamino, Yoichiro Iwakura, Tomiharu Niida, Kikuo Isoda, Yayoi Sato-Okabayashi, Fumie Ohtomo
Publikováno v:
Clinical Science. 135:2035-2048
Clinical hypertension (HT) is associated with renal inflammation and elevated circulating levels of proinflammatory cytokines. Interleukin (IL)-1 receptor antagonist (IL-1Ra) is one of the most important anti-inflammatory cytokines and plays a crucia
Autor:
Koji Akita, Kikuo Isoda, Yayoi Sato-Okabayashi, Tomoyasu Kadoguchi, Kenichi Kitamura, Fumie Ohtomo, Kazunori Shimada, Hiroyuki Daida
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
IκBNS is a nuclear IκB protein which negatively regulates nuclear factor-κB activity. We demonstrated that IκBNS deficiency accelerates atherosclerosis in LDL receptor-deficient (LDLr−/−) mice via increased interleukin (IL)-6 production by ma
Externí odkaz:
https://doaj.org/article/75068cd063bf423e8932693a44959161
Autor:
Koji Akita, Kikuo Isoda, Fumie Ohtomo, Sarasa Isobe, Tomiharu Niida, Yayoi Sato-Okabayashi, Motoaki Sano, Kazunori Shimada, Yoichiro Iwakura, Tohru Minamino
Publikováno v:
Clinical Science; Sep2021, Vol. 135 Issue 17, p2035-2048, 14p
Blocking of interleukin-1 suppresses both angiotensin II-induced renal inflammation and hypertension
Autor:
Fumie Ohtomo, Tomoyasu Kadoguchi, T Niida, Kenichi Kitamura, Kazunori Shimada, Kikuo Isoda, Y. Okabayashi
Publikováno v:
European Heart Journal. 41
Background Clinical hypertension is associated with renal inflammation and elevated circulating levels of proinflammatory cytokines. IL-1 receptor antagonist (IL-1Ra) is one of the most important anti-inflammatory cytokines and plays a crucial role i
Autor:
Kikuo Isoda, Fumie Ohtomo, Kazunori Shimada, Hiroyuki Daida, Kenichi Kitamura, Koji Akita, Tomoyasu Kadoguchi, Yayoi Sato-Okabayashi, Kai Ishii
Publikováno v:
European Heart Journal. 39
Autor:
Kikuo Isoda, Koji Akita, Kenichi Kitamura, Sarasa Isobe, Kazunori Shimada, Tomoyasu Kadoguchi, Yoichiro Iwakura, Motoaki Sano, Yayoi Sato-Okabayashi, Fumie Ohtomo, Hiroyuki Daida
Publikováno v:
International journal of cardiology. 270
Background Angiotensin II (Ang II) activates components of the inflammatory cascade, which promotes hypertension and development of abdominal aortic aneurysm (AAA). This study aimed to elucidate the effects of an IL-1 receptor antagonist (IL-1Ra) and
Autor:
Tomoyasu Kadoguchi, Fumie Ohtomo, Kikuo Isoda, Koji Akita, Kenichi Kitamura, Kazunori Shimada, Yayoi Sato-Okabayashi, Hiroyuki Daida
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
IκBNS is a nuclear IκB protein which negatively regulates nuclear factor-κB activity. We demonstrated that IκBNS deficiency accelerates atherosclerosis in LDL receptor-deficient (LDLr−/−) mice via increased interleukin (IL)-6 production by ma