Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Fumiaki Nakayama"'
Autor:
Taichi Miura, PhD, Mitsuko Kawano, PhD, Keiko Takahashi, BS, Noriyuki Yuasa, PhD, Masato Habu, Fumie Kimura, MS, Toru Imamura, PhD, Fumiaki Nakayama, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 3, Pp 100900- (2022)
Purpose: Many growth factors, such as fibroblast growth factors (FGFs), are useful for the treatment or prevention of radiation damage after radiation therapy. Although heparin can be supplemented to increase the therapeutic effects of FGFs, it posse
Externí odkaz:
https://doaj.org/article/098f875e342d4176b49b98978cca1976
Autor:
Mitsuko Kawano, Taichi Miura, Mayumi Fujita, Sachiko Koike, Kaori Imadome, Atsuko Ishikawa, Takeshi Yasuda, Toru Imamura, Takashi Imai, Fumiaki Nakayama
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 14, Iss , Pp 8-16 (2019)
Background and purpose: Carbon ion (C-ion) beams are concentrated to irradiate pancreatic carcinoma in the upper abdomen; however, this radiotherapy potentially causes adverse reactions in the gastrointestinal tract. FGF1 is a candidate radioprotecto
Externí odkaz:
https://doaj.org/article/9e62363177bd486aa7c889ae9ca45e76
Autor:
Taichi Miura, Mayumi Fujita, Mitsuko Kawano, Kaori Imadome, Takeshi Yasuda, Shoko Nishihara, Toru Imamura, Mikio Masuzawa, Takashi Imai, Fumiaki Nakayama
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 7, Iss , Pp 83-90 (2017)
Background and purpose: Angiosarcoma is associated with a poor prognosis and is treated with radiotherapy. Although FGF1 is a potential radioprotector, the influence of FGF1 on the malignancy of angiosarcoma remains unknown. Materials and methods: Hi
Externí odkaz:
https://doaj.org/article/cafa6260ed84448db63d923f6577f822
Autor:
Mitsuko Kawano, PhD, Sachiko Umeda, BS, Takeshi Yasuda, PhD, Mayumi Fujita, PhD, Atsuko Ishikawa, BS, Toru Imamura, PhD, Takashi Imai, PhD, Fumiaki Nakayama, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 1, Iss 3, Pp 170-181 (2016)
Purpose: Telogen (resting phase) hair follicles (HFs) are more radioresistant than their anagen (growth phase) counterparts. Fibroblast growth factor (FGF) 18 is strongly expressed in telogen HFs to maintain the telogen phase, whereas several other F
Externí odkaz:
https://doaj.org/article/602d3c872f4641ee83b58b6518549dc5
Autor:
Takeshi Yasuda, Wataru Kagawa, Tomoo Ogi, Takamitsu A Kato, Takehiro Suzuki, Naoshi Dohmae, Kazuya Takizawa, Yuka Nakazawa, Matthew D Genet, Mika Saotome, Michio Hama, Teruaki Konishi, Nakako Izumi Nakajima, Masaharu Hazawa, Masanori Tomita, Manabu Koike, Katsuko Noshiro, Kenichi Tomiyama, Chizuka Obara, Takaya Gotoh, Ayako Ui, Akira Fujimori, Fumiaki Nakayama, Fumio Hanaoka, Kaoru Sugasawa, Ryuichi Okayasu, Penny A Jeggo, Katsushi Tajima
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007277 (2018)
The p300 and CBP histone acetyltransferases are recruited to DNA double-strand break (DSB) sites where they induce histone acetylation, thereby influencing the chromatin structure and DNA repair process. Whether p300/CBP at DSB sites also acetylate n
Externí odkaz:
https://doaj.org/article/e1679cb73def4710aa1a8cba50af9b31
Autor:
Taichi Miura, Mitsuko Kawano, Keiko Takahashi, Noriyuki Yuasa, Masato Habu, Fumie Kimura, Toru Imamura, Fumiaki Nakayama
Publikováno v:
Advances in radiation oncology. 7(3)
Many growth factors, such as fibroblast growth factors (FGFs), are useful for the treatment or prevention of radiation damage after radiation therapy. Although heparin can be supplemented to increase the therapeutic effects of FGFs, it possesses stro
Autor:
Mikio Masuzawa, Kaori Imadome, Taichi Miura, Fumiaki Nakayama, Toru Imamura, Takeshi Yasuda, Takashi Imai, Mayumi Fujita, Mitsuko Kawano, Shoko Nishihara
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 7, Iss, Pp 83-90 (2017)
Clinical and Translational Radiation Oncology
Clinical and Translational Radiation Oncology
Highlights • Angiosarcoma is associated with a poor prognosis and is treated with radiotherapy. • Highly stable FGF1 mutants exhibit stronger mitogenic activity than wild-type FGF1 and are candidates for radioprotectors. • They were examined as
Autor:
Mitsuko Kawano, Hayato Ota, Habu Masato, Noriyuki Yuasa, Taichi Miura, Fumiaki Nakayama, Shoko Nishihara
Publikováno v:
Biochemical and biophysical research communications. 518(3)
Human induced pluripotent stem (hiPS) cells are attracting attention as a tool for regenerative medicine. However, several problems need to be overcome for their widespread and safe use, for example, the high cost of maintaining hiPS cells and the po
Autor:
Hisahiro Matsubara, Yoshimi Shoji, Fumiaki Nakayama, Takeshi Yasuda, Mayumi Fujita, Kaori Imadome, Shigeru Yamada, Takashi Imai, Tetsuro Isozaki
Publikováno v:
International Journal of Oncology
C-ion radiotherapy is associated with improved local control and survival in several types of tumors. Although C-ion irradiation is widely reported to effectively induce DNA damage in tumor cells, the effects of irradiation on proteins, such as prote
Autor:
Katsuko Noshiro, Katsushi Tajima, Naoshi Dohmae, Takamitsu A. Kato, Chizuka Obara, Akira Fujimori, Takaya Gotoh, Kazuya Takizawa, Masaharu Hazawa, Manabu Koike, Tomoo Ogi, Fumiaki Nakayama, Masanori Tomita, Nakako Izumi Nakajima, Mika Saotome, Teruaki Konishi, Kenichi Tomiyama, Matthew D. Genet, Fumio Hanaoka, Ayako Ui, Takehiro Suzuki, Takeshi Yasuda, Penny A. Jeggo, Yuka Nakazawa, Michio Hama, Ryuichi Okayasu, Wataru Kagawa, Kaoru Sugasawa
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007277 (2018)
PLoS Genetics
PLoS Genetics
The p300 and CBP histone acetyltransferases are recruited to DNA double-strand break (DSB) sites where they induce histone acetylation, thereby influencing the chromatin structure and DNA repair process. Whether p300/CBP at DSB sites also acetylate n