Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Fumei Zhong"'
Autor:
Lei Wang, Jia Gao, Rongsheng Ma, Yaqian Liu, Mingqing Liu, Fumei Zhong, Jie Hu, Shuju Li, Jihui Wu, Hualiang Jiang, Jiahai Zhang, Ke Ruan
Publikováno v:
Magnetic Resonance Letters, Vol 2, Iss 2, Pp 107-118 (2022)
Considerable developments have been observed in fragment-based lead/drug discovery (FBLD/FBDD) recently, with four drugs approved and many others under investigation. Nuclear magnetic resonance (NMR) has gained increasing popularity in FBLD due to it
Externí odkaz:
https://doaj.org/article/c2fc70698ead422fb2c1e436641197ab
Autor:
Ke Ruan, Jiahai Zhang, Yaqian Liu, Lei Wang, Jihui Wu, Jie Hu, Shuju Li, Hualiang Jiang, Mingqing Liu, Fumei Zhong, Rongsheng Ma, Jia Gao
Publikováno v:
Magnetic Resonance Letters. 2:107-118
Considerable developments have been observed in fragment-based lead/drug discovery (FBLD/FBDD) recently, with four drugs approved and many others under investigation. Nuclear magnetic resonance (NMR) has gained increasing popularity in FBLD due to it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b17d1ac1c15e1ee1d9ba4a1ebb26ad
https://doi.org/10.1016/j.mrl.2021.100025
https://doi.org/10.1016/j.mrl.2021.100025
RNF31 is identified in human proteins and is involved in activities of the linear ubiquitin chain assembly complex (LUBAC) and cell growth. RNF31 plays an important role in LUBAC-mediated ubiquitination. Here, we report the backbone and side-chain re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518b7c68b6f64f8788ca10a9b2e41d30
https://doi.org/10.21203/rs.3.rs-2442972/v1
https://doi.org/10.21203/rs.3.rs-2442972/v1
Autor:
Jiao Li, Fumei Zhong, Mingwei Li, Yaqian Liu, Lei Wang, Mingqing Liu, Fudong Li, Jiahai Zhang, Jihui Wu, Yunyu Shi, Zhiyong Zhang, Xiaoming Tu, Ke Ruan, Jia Gao
Publikováno v:
Journal of medicinal chemistry. 65(22)
Severe acute respiratory syndrome-coronavirus-1/2 (SARS-CoV-1/2) macrodomain 3 (Mac3) is critical for replication and transcription of the viral genome and is therefore a potential therapeutic target. Here, we solved the crystal structure of SARS-CoV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44151105fac213beda19742326af5a86
https://pubmed.ncbi.nlm.nih.gov/36356292
https://pubmed.ncbi.nlm.nih.gov/36356292