Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III)

Autor: Maiwald, Christian A, Annink, Kim V, Ruediger, Mario, Benders, Manon JNL, van Bel, Frank, Allegaert, Karel, Naulaers, Gunnar, Bassler, Dirk, Kleberma-Schrehof, Katrin, Vento, Maximo, Guimaraes, Hercilia, Stiris, Tom, Cattarossi, Luigi, Metsaeranta, Marjo, Vanhatalo, Sampsa, Mazela, Jan, Metsvaht, Tuuli, Jacobs, Yannique, Franz, Axel R, Poets, Christian F, Benders, Manon, Klebermass-Schrehof, Katrin, Metsaranta, Marjo, van Veldhuizen, Cees KW, Engel, Corinna, von Oldershausen, Gabriele, Bergmann, Iris, Weiss, Monika, Wichera, Caroline JBR, Eichhorn, Andreas, Raubuch, Michael, Schuler, Birgit, Lameris, Bas, van der Vlught-Meijer, Roselinda, Kliniken, Tirol, Griesmaier, Elke, Salzburg, Uniklinikum, Brandner, Johannes, Tackoen, Marie, Reibel, Ruth, Cornette, Luc, Viellevoye, Liege Renaud, Saik, Pille, Kaar, Ruth, Andresson, Pille, Carus, CG, Winkler, Stefan, Hoehn, Thomas, Teig, Norbert, Schroth, Michael, Fusch, Christoph, Thome, Ulrich H, Ehrhardt, Harald, Mauro, Isabella, Baraldi, Eugenio, Carnielli, Virgilio, Paterlini, Monza Giuseppe, Napolitano, Marcello, Faldini, Francesca, Lista, Gian-Luca, Barbarini, Mario, Pagani, Laura, Anna, S, Mastretta, Emmanuele, Vento, Giovanni, Fumagalli, Milano Monica, Binotti, Novara Marco, van Weissenbruch, Mirjam M, van Straaten, Henrica LM, Dudink, Jeroen, Derks, Jan B, de Boer, Inge P, Meijssen, Clemens B, de Haan, Timo R, van Rooij, Linda G, van Hillegersberg, Jacqueline L, van Dongen, Minouche, Dassel, ACM, Dijkman, Koen P, van Houten, Marlies A, van der Schoor, Sophie RD, Nestaas, Eirik, Karpinski, Lukas, Vilan, Ana I, de Pinho, Liliana Flores, Ferraz, Claudia, Pereira, Almerinda, Barroso, Rosalina, da Graca, Mendes, Tome, Teresa, Pinto, Filomena, Martinez Rodilla, Juan, Luz, Maria, Pico, Couce, Camprubi Camprubi, Marta, Hurtado Suazo, Jose Antonio, Valverde, Eva, Fernandez Lorenzo, Jose Ramon, Martinez Orgado, Jose, Boix, Hector, Jimenez Parrilla, Francisco, Blanco, Dorotea, Teresa Moral-Pumarega, Maria, Maletzki, Julia, Knoepfli, Claudia, Hagmann, Cornelia, Kleber, Michael, Schulzke, Sven, Stocker, Martin, Birkenmaier, Andre, Riedel, Thomas

BACKGROUND: Perinatal asphyxia and resulting hypoxic-ischemic encephalopathy is a major cause of death and long-term disability in term born neonates. Up to 20,000 infants each year are affected by HIE in Europe and even more in regions with lower le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1131::4035f0d8b0ac81d1b28121ff5779d3c7
https://lirias.kuleuven.be/handle/123456789/638879