Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fulvio Serra"'
Autor:
Isabella Molinari, Paolo Barassi, Sergio De Munari, Nicoletta Almirante, Alberto Cerri, Piero Melloni, Giuseppe Marazzi, Alessandra Benicchio, Fulvio Serra
Publikováno v:
Journal of Medicinal Chemistry. 45:189-207
A series of 5-substituted (3aS,7aR)-7a-methylperhydroinden-3a-ol derivatives bearing a 1(S)-(omega-aminoalkoxy)iminoalkyl or -alkenyl substituent was synthesized, starting from the Hajos-Parrish ketol 47, as simplified analogues of very potent 17beta
Publikováno v:
Journal of Medicinal Chemistry. 40:3484-3488
A series of digitalis-like compounds, with the lactone ring shifted from the original position through a spacer or replaced by a series of guanylhydrazone substituent-bearing chains, was synthesized and evaluated for inhibition of Na+,K(+)-ATPase and
Publikováno v:
ChemInform. 29
Autor:
Fulvio Serra, Antonio Schiavone, Maria Pia Zappavigna, Roberto Rossi, Alessandra Benicchio, Luisa Quadri, P. Melloni, Giorgio Fedrizzi, Enzio Ragg, Patrizia Ferrari, Paolo Barassi, Marco Santagostino, Rosella Micheletti, Nicoletta Almirante, Alberto Cerri
Publikováno v:
Journal of medicinal chemistry. 43(12)
A series of digitalis-like compounds with a 17-aminoalkoxyiminoalkyl or -alkenyl substituent was synthesized and evaluated for inhibition of Na(+),K(+)-ATPase and for inotropic activity. The highest inhibition was found with compounds having the subs
Autor:
Isabella Molinari, Marco Ruggiero, Giuseppe Bianchi, Fulvio Serra, Laura Soldati, Sergio Salardi, B. R. Barber
Publikováno v:
Biochemical and biophysical research communications. 175(2)
We studied calpastatin activity in erythrocytes of Milan hypertensive and prehypertensive rats, in their normotensive controls, in F1 and F2 hybrids, and in two inbred strains derived from F2, one hypertensive and the other normotensive. Our results