Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Fulvio D'angelo"'
Autor:
Leland S. Hu, Fulvio D’Angelo, Taylor M. Weiskittel, Francesca P. Caruso, Shannon P. Fortin Ensign, Mylan R. Blomquist, Matthew J. Flick, Lujia Wang, Christopher P. Sereduk, Kevin Meng-Lin, Gustavo De Leon, Ashley Nespodzany, Javier C. Urcuyo, Ashlyn C Gonzales, Lee Curtin, Erika M. Lewis, Kyle W. Singleton, Timothy Dondlinger, Aliya Anil, Natenael B. Semmineh, Teresa Noviello, Reyna A. Patel, Panwen Wang, Junwen Wang, Jennifer M. Eschbacher, Andrea Hawkins-Daarud, Pamela R. Jackson, Itamar S. Grunfeld, Christian Elrod, Gina L. Mazza, Sam C. McGee, Lisa Paulson, Kamala Clark-Swanson, Yvette Lassiter-Morris, Kris A. Smith, Peter Nakaji, Bernard R. Bendok, Richard S. Zimmerman, Chandan Krishna, Devi P. Patra, Naresh P. Patel, Mark Lyons, Matthew Neal, Kliment Donev, Maciej M. Mrugala, Alyx B. Porter, Scott C. Beeman, Todd R. Jensen, Kathleen M. Schmainda, Yuxiang Zhou, Leslie C. Baxter, Christopher L. Plaisier, Jing Li, Hu Li, Anna Lasorella, C. Chad Quarles, Kristin R. Swanson, Michele Ceccarelli, Antonio Iavarone, Nhan L. Tran
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Sampling restrictions have hindered the comprehensive study of invasive non-enhancing (NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present an integrated multi-omic analysis of spatially matched molecular
Externí odkaz:
https://doaj.org/article/a2809ec273b7446289807a553cea6a7f
Autor:
Lujia Wang, Hairong Wang, Fulvio D'Angelo, Lee Curtin, Christopher P Sereduk, Gustavo De Leon, Kyle W Singleton, Javier Urcuyo, Andrea Hawkins-Daarud, Pamela R Jackson, Chandan Krishna, Richard S Zimmerman, Devi P Patra, Bernard R Bendok, Kris A Smith, Peter Nakaji, Kliment Donev, Leslie C Baxter, Maciej M Mrugała, Michele Ceccarelli, Antonio Iavarone, Kristin R Swanson, Nhan L Tran, Leland S Hu, Jing Li
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0299267 (2024)
Background and objectiveGlioblastoma (GBM) is one of the most aggressive and lethal human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for treatment. Biopsy is invasive, which motivates the development of non-invasive, M
Externí odkaz:
https://doaj.org/article/b57d4faef51a40fca14cffc4c306cabd
Autor:
Sang Bae Lee, Luciano Garofano, Aram Ko, Fulvio D’Angelo, Brulinda Frangaj, Danika Sommer, Qiwen Gan, KyeongJin Kim, Timothy Cardozo, Antonio Iavarone, Anna Lasorella
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Tissue-specific transcriptional activity is silenced in mitotic cells. Here the authors reveal a general phosphorylation-dependent mechanism of recognition for the anaphase-promoting complex (APC) substrates, and show that the APC targets ID2 during
Externí odkaz:
https://doaj.org/article/6f441f5daf114e89a17e33b1ead8f3cd
Autor:
Aram Ko, Mohammad Hasanain, Young Taek Oh, Fulvio D'Angelo, Danika Sommer, Brulinda Frangaj, Suzanne Tran, Franck Bielle, Bianca Pollo, Rosina Paterra, Karima Mokhtari, Rajesh Kumar Soni, Matthieu Peyre, Marica Eoli, Laura Papi, Michel Kalamarides, Marc Sanson, Antonio Iavarone, Anna Lasorella
Publikováno v:
Cancer Discovery. 13:702-723
LZTR1 is the substrate-specific adaptor of a CUL3-dependent ubiquitin ligase frequently mutated in sporadic and syndromic cancer. We combined biochemical and genetic studies to identify LZTR1 substrates and interrogated their tumor-driving function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6239b16e0f2ba85ffa82f2f163c00d3b
https://doi.org/10.1158/2159-8290.cd-22-0376
https://doi.org/10.1158/2159-8290.cd-22-0376
Autor:
Anna Lasorella, Antonio Iavarone, Marc Sanson, Michel Kalamarides, Laura Papi, Marica Eoli, Matthieu Peyre, Rajesh Kumar Soni, Karima Mokhtari, Rosina Paterra, Bianca Pollo, Franck Bielle, Suzanne Tran, Brulinda Frangaj, Danika Sommer, Fulvio D'Angelo, Young Taek Oh, Mohammad Hasanain, Aram Ko
Phenotype alterations in the liver and brain of Lztr1-deleted mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245f881dbdc37d67dae9f5060eddd2d5
https://doi.org/10.1158/2159-8290.22542445.v1
https://doi.org/10.1158/2159-8290.22542445.v1
Autor:
Anna Lasorella, Antonio Iavarone, Marc Sanson, Michel Kalamarides, Laura Papi, Marica Eoli, Matthieu Peyre, Rajesh Kumar Soni, Karima Mokhtari, Rosina Paterra, Bianca Pollo, Franck Bielle, Suzanne Tran, Brulinda Frangaj, Danika Sommer, Fulvio D'Angelo, Young Taek Oh, Mohammad Hasanain, Aram Ko
LZTR1 is the substrate-specific adaptor of a CUL3-dependent ubiquitin ligase frequently mutated in sporadic and syndromic cancer. We combined biochemical and genetic studies to identify LZTR1 substrates and interrogated their tumor-driving function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883df427a8e24b8599e910acc12db611
https://doi.org/10.1158/2159-8290.c.6549922.v1
https://doi.org/10.1158/2159-8290.c.6549922.v1
Autor:
Anna Lasorella, Antonio Iavarone, Marc Sanson, Michel Kalamarides, Laura Papi, Marica Eoli, Matthieu Peyre, Rajesh Kumar Soni, Karima Mokhtari, Rosina Paterra, Bianca Pollo, Franck Bielle, Suzanne Tran, Brulinda Frangaj, Danika Sommer, Fulvio D'Angelo, Young Taek Oh, Mohammad Hasanain, Aram Ko
Table S1. List of ubiquitylated peptides from DiGly proteomics assay. Table S2. List of proteins differentially abundant in LZTR1-/- compared toLZTR1+/+ cells quantified by TMT.Table S3. List of top scoring LZTR1 interacting proteins from immunopreci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6439204b4a85d07591543260bc42c163
https://doi.org/10.1158/2159-8290.22542433.v1
https://doi.org/10.1158/2159-8290.22542433.v1
Autor:
Massimo Pancione, Aldo Scarpa, Vittorio Colantuoni, Michele Ceccarelli, Giuseppe Viglietto, Luca Mastracci, Federica Grillo, Fulvio D'angelo, Fortunato Lonardo, Claudio Ghimenton, Guido Giordano, Massimo Delledonne, Luciano Xumerle, Marianna Garonzi, Enrico Molinari, Jacopo Giuliani, Lina Sabatino, Tommaso Colangelo, Elisabetta Baritono, Duarte Mendes Oliveira, Donatella Malanga, Michele Simbolo, Carmelo Laudanna, Ugnius Mickys, Hye Seung Han, Alberto Ferrarini, Pietro Parcesepe, Erminia Manfrin, Andrea Remo
The file contains supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2dd3eade6eed753e8ca1cdbbf0190be
https://doi.org/10.1158/1541-7786.22512418.v1
https://doi.org/10.1158/1541-7786.22512418.v1
Autor:
Massimo Pancione, Aldo Scarpa, Vittorio Colantuoni, Michele Ceccarelli, Giuseppe Viglietto, Luca Mastracci, Federica Grillo, Fulvio D'angelo, Fortunato Lonardo, Claudio Ghimenton, Guido Giordano, Massimo Delledonne, Luciano Xumerle, Marianna Garonzi, Enrico Molinari, Jacopo Giuliani, Lina Sabatino, Tommaso Colangelo, Elisabetta Baritono, Duarte Mendes Oliveira, Donatella Malanga, Michele Simbolo, Carmelo Laudanna, Ugnius Mickys, Hye Seung Han, Alberto Ferrarini, Pietro Parcesepe, Erminia Manfrin, Andrea Remo
Centrosome anomalies contribute to tumorigenesis, but it remains unclear how they are generated in lethal cancer phenotypes. Here, it is demonstrated that human microsatellite instable (MSI) and BRAFV600E-mutant colorectal cancers with a lethal rhabd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c9590a1287843f3fbd20ae125c60be9
https://doi.org/10.1158/1541-7786.c.6540235.v1
https://doi.org/10.1158/1541-7786.c.6540235.v1
Autor:
Massimo Pancione, Aldo Scarpa, Vittorio Colantuoni, Michele Ceccarelli, Giuseppe Viglietto, Luca Mastracci, Federica Grillo, Fulvio D'angelo, Fortunato Lonardo, Claudio Ghimenton, Guido Giordano, Massimo Delledonne, Luciano Xumerle, Marianna Garonzi, Enrico Molinari, Jacopo Giuliani, Lina Sabatino, Tommaso Colangelo, Elisabetta Baritono, Duarte Mendes Oliveira, Donatella Malanga, Michele Simbolo, Carmelo Laudanna, Ugnius Mickys, Hye Seung Han, Alberto Ferrarini, Pietro Parcesepe, Erminia Manfrin, Andrea Remo
Supplementary Table 1. Clinicopathological, immunohistochemical and molecular features of the 12 rhabdoid colorectal cancers7 Supplementary Table 2. Somatic mutations of candidate genes (15 out of 20 are reported) shared by the two rhabdoid cancers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e70ed8632c3c87604dd400505e1175
https://doi.org/10.1158/1541-7786.22512415
https://doi.org/10.1158/1541-7786.22512415