Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fulvia Cerruti"'
Autor:
Jessica Bordini, Federica Morisi, Fulvia Cerruti, Paolo Cascio, Clara Camaschella, Paolo Ghia, Alessandro Campanella
Publikováno v:
Cancers, Vol 12, Iss 4, p 970 (2020)
Adaptation to import iron for proliferation makes cancer cells potentially sensitive to iron toxicity. Iron loading impairs multiple myeloma (MM) cell proliferation and increases the efficacy of the proteasome inhibitor bortezomib. Here, we defined t
Externí odkaz:
https://doaj.org/article/ebd61591cf1b4aac960fc72e8a3b16c8
Autor:
Fulvia Cerruti, Marina Martano, Claudio Petterino, Enrico Bollo, Emanuela Morello, Renato Bruno, Paolo Buracco, Paolo Cascio
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 11, Pp 960-969 (2007)
In human tumors, changes in the surface expression and/or function of major histocompatibility complex (MHC) class I antigens are frequently found and may provide malignant cells with a mechanism to escape control of the immune system. This altered h
Externí odkaz:
https://doaj.org/article/b7ae2d14b1754bbaa39ad022f52d1d6b
Autor:
Jean-Yves Alejandro Frayssinhes, Fulvia Cerruti, Justine Laulin, Angela Cattaneo, Angela Bachi, Sebastien Apcher, Olivier Coux, Paolo Cascio
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(1)
PA28γ is a nuclear activator of the 20S proteasome that, unlike the 19S regulatory particle, stimulates hydrolysis of several substrates in an ATP- and ubiquitin-independent manner and whose exact biological functions and molecular mechanism of acti
Autor:
Paolo Ghia, Federica Morisi, Fulvia Cerruti, Paolo Cascio, Alessandro Campanella, Jessica Bordini, Clara Camaschella
Publikováno v:
Cancers
Cancers, Vol 12, Iss 970, p 970 (2020)
Volume 12
Issue 4
Cancers, Vol 12, Iss 970, p 970 (2020)
Volume 12
Issue 4
Adaptation to import iron for proliferation makes cancer cells potentially sensitive to iron toxicity. Iron loading impairs multiple myeloma (MM) cell proliferation and increases the efficacy of the proteasome inhibitor bortezomib. Here, we defined t
Autor:
Fulvia Cerruti, Simone Cenci, Beatrice Alessandria, Chiara Salio, Gianmauro Numico, Silvia Mioletti, Paolo Cascio, Giovanni Donati, Laura Oliva, Genny Jocolle, Luca Paglietti
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Based on promising results in preclinical models, clinical trials have been performed to evaluate the efficacy of the first-in-class proteasome inhibitor bortezomib towards malignant pleural mesothelioma (MPM), an aggressive cancer arising from the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79c3f632a15cae81726df02b554dd0f
http://hdl.handle.net/2318/1705355
http://hdl.handle.net/2318/1705355
Publikováno v:
Veterinary Immunology and Immunopathology. 166:43-49
Information on the biochemical properties of proteasomes is lacking or, at best, only fragmentary for most species of veterinary interest. Moreover, direct comparison of the limited data available on the enzymatic features of proteasomes in domestic
Autor:
Mary Raule, Gunnar Dittmar, Ami Navon, Fulvia Cerruti, Julia Kikuchi, Rebekka Migotti, Angela Bachi, Nadia Benaroudj, Paolo Cascio
Publikováno v:
Chemistry & Biology. 21:470-480
Summary The specific roles that immunoproteasome variants play in MHC class I antigen presentation are unknown at present. To investigate the biochemical properties of different immunoproteasome forms and unveil the molecular mechanisms of PA28 activ
Autor:
D. de Andrés, Pier Luigi Acutis, Ramsés Reina, Margherita Proffiti, Helena Crespo, Luigi Bertolotti, Paolo Cascio, Fulvia Cerruti, Sergio Rosati
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Small ruminant lentiviruses (SRLV) globally affect welfare and production of sheep and goats and are mainly controlled through elimination of infected animals, independently of the viral kinetics within the single animal. Control programs are based o
Autor:
Enrico Milan, Silvia Mangiacavalli, Paola Rognoni, Simona Casarini, Giampaolo Merlini, Paolo Milani, Fulvia Cerruti, Magda Marcatti, Thierry Touvier, Simone Cenci, Ugo Orfanelli, Alessandro Corso, Paolo Cascio, Massimo Resnati, Andrea Orsi, Giovanni Palladini, Laura Oliva, Fabio Ciceri, Andrea Raimondi
Publikováno v:
Blood. 129(15)
Systemic light chain (AL) amyloidosis is caused by the clonal production of an unstable immunoglobulin light chain (LC), which affects organ function systemically. Although pathogenic LCs have been characterized biochemically, little is known about t
Autor:
Luigi Bertolotti, Fulvia Cerruti, Ramsés Reina, Beatriz Amorena, Daniele De Meneghi, Margherita Profiti, M. Juganaru, Paolo Cascio, Sergio Rosati
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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Genotype E of small ruminant lentivirus has been recently described in goats from different breeds in Italy. Genotype E infection may differ from known genotypes since deletions of dUTPase and VPR proteins have been confirmed in different independent