Zobrazeno 1 - 10 of 139 pro vyhledávání: '"Fulvia, Felluga"'
1
Akademický článek
Identification and evaluation of antiviral activity of novel compounds targeting SARS-CoV-2 virus by enzymatic and antiviral assays, and computational analysis
Autor: Ivana Nemčovičová, Katarína Lopušná, Iveta Štibrániová, Fabio Benedetti, Federico Berti, Fulvia Felluga, Sara Drioli, Mattia Vidali, Jaroslav Katrlík, Lucia Pažitná, Alena Holazová, Jana Blahutová, Simona Lenhartová, Monika Sláviková, Boris Klempa, Miroslav Ondrejovič, Daniela Chmelová, Barbora Legerská, Stanislav Miertuš, Mária Klacsová, Daniela Uhríková, Lukáš Kerti, Vladimír Frecer
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractThe viral genome of the SARS-CoV-2 coronavirus, the aetiologic agent of COVID-19, encodes structural, non-structural, and accessory proteins. Most of these components undergo rapid genetic variations, though to a lesser extent the essential v
Externí odkaz: https://doaj.org/article/1ab0d8cfa120432f8905bf2f4c7f5d07
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2
Akademický článek
In Vitro and In Vivo Evaluation of the Effects of Drug 2c and Derivatives on Ovarian Cancer Cells
Autor: Marianna Maddaloni, Rossella Farra, Barbara Dapas, Fulvia Felluga, Fabio Benedetti, Federico Berti, Sara Drioli, Mattia Vidali, Maja Cemazar, Urska Kamensek, Claudio Brancolini, Erminio Murano, Francesca Maremonti, Mario Grassi, Alice Biasin, Flavio Rizzolio, Enrico Cavarzerani, Bruna Scaggiante, Roberta Bulla, Andrea Balduit, Giuseppe Ricci, Gabriella Zito, Federico Romano, Serena Bonin, Eros Azzalini, Gabriele Baj, Domenico Tierno, Gabriele Grassi
Publikováno v: Pharmaceutics, Vol 16, Iss 5, p 664 (2024)
Background: The identification of novel therapeutic strategies for ovarian cancer (OC), the most lethal gynecological neoplasm, is of utmost urgency. Here, we have tested the effectiveness of the compound 2c (4-hydroxy-2,6-bis(4-nitrobenzylidene)cycl
Externí odkaz: https://doaj.org/article/9cda9d91d298443aa1fd39a5f208d7da
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3
Akademický článek
Molecular Ballet: Investigating the Complex Interaction between Self-Assembling Dendrimers and Human Serum Albumin via Computational and Experimental Methods
Autor: Gabriele Cavalieri, Domenico Marson, Nicoletta Giurgevich, Rachele Valeri, Fulvia Felluga, Erik Laurini, Sabrina Pricl
Publikováno v: Pharmaceutics, Vol 16, Iss 4, p 533 (2024)
Dendrimers, intricate macromolecules with highly branched nanostructures, offer unique attributes including precise control over size, shape, and functionality, making them promising candidates for a wide range of biomedical applications. The explora
Externí odkaz: https://doaj.org/article/3bd63c41819b4bd0ae73568d58da57cd
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8
Akademický článek
One Pot Synthesis of Micromolar BACE-1 Inhibitors Based on the Dihydropyrimidinone Scaffold and Their Thia and Imino Analogues
Autor: Jessica Bais, Fabio Benedetti, Federico Berti, Iole Cerminara, Sara Drioli, Maria Funicello, Giorgia Regini, Mattia Vidali, Fulvia Felluga
Publikováno v: Molecules, Vol 25, Iss 18, p 4152 (2020)
A library of dihydropyrimidinones was synthesized via a “one-pot” three component Biginelli reaction using different aldehydes in combination with β-dicarbonyl compounds and urea. Selected 2-thiooxo and 2-imino analogs were also obtained with th
Externí odkaz: https://doaj.org/article/5f43fc193c9c4cd89b8d7d919e79250c
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9
Nanomechanical Characterization of Ovarian Cancer Cell Lines as a Marker of Response to 2c Treatment
Autor: Domenico Tierno, Eros Azzalini, Rossella Farra, Sara Drioli, Fulvia Felluga, Marco Lazzarino, Gabriele Grassi, Barbara Dapas, Serena Bonin
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7230
Epithelial ovarian cancers (EOCs) are a heterogeneous group of tumors with different molecular and clinical features. In past decades, few improvements have been achieved in terms of EOC management and treatment efficacy, such that the 5-year surviva
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93875df9c7086f965bb48833f958b546
https://doi.org/10.3390/ijms24087230
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10
Akademický článek
New Chiral P-N Ligands for the Regio- and Stereoselective Pd-Catalyzed Dimerization of Styrene
Autor: Sergio Castillon, Fulvia Felluga, Angelo Meduri, Ennio Zangrando, Lidia Fanfoni, Barbara Milani
Publikováno v: Molecules, Vol 16, Iss 2, Pp 1804-1824 (2011)
Two new chiral, enantiomerically pure, hybrid P-N ligands, namely (2R,5S)-2-phenyl-3-(2-pyridyl)-1,3-diaza-2-phosphanicyclo[3,3,0]octan-4-one (1) and (2R,5S)-2-phenyl-3-(2-pyridyl)-1,3-diaza-2-phosphanicyclo[3,3,0]octane (2), have been synthesized st
Externí odkaz: https://doaj.org/article/716107766c2d4d79aa25d94247debd4d
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